Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nicotine induces self-renewal of pancreatic cancer stem cells via neurotransmitter-driven activation of sonic hedgehog signalling

(2016) Mohammed H. Al-Wadei et al.   EUROPEAN JOURNAL OF CANCER

TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation

(2016) Dafni-Eleftheria Pefani et al.   MOLECULAR CELL

Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors

(2016) Courtney Schaal et al.   PLoS One

CD133, Selectively Targeting the Root of Cancer

(2016) Jörg Schmohl et al.   Toxins

New Insights into the Crossroads between EMT and Stemness in the Context of Cancer

(2016) Isabel Fabregat et al.   Journal of Clinical Medicine

Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal

(2016) Fabrizio Marcucci et al.   Frontiers in Oncology

 -Arrestin-1 Mediates Nicotine-Induced Metastasis through E2F1 Target Genes That Modulate Epithelial-Mesenchymal Transition

(2015) S. Pillai et al.   CANCER RESEARCH

Recent progress in revealing the biological and medical significance of the non-neuronal cholinergic system

(2015) Sergei A. Grando et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A gp130–Src–YAP module links inflammation to epithelial regeneration

(2015) Koji Taniguchi et al.   NATURE

Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy

(2015) Carolina Vicente-Dueñas et al.   SEMINARS IN CANCER BIOLOGY

YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells

(2015) Namrata Bora-Singhal et al.   STEM CELLS

Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis

(2015) Smitha Pillai et al.   Nature Communications

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

(2015) Julien Fitamant et al.   Cell Reports

Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer

(2015) Namrata Bora-Singhal et al.   NEOPLASIA

Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ β-arrestin-1 dependent manner in NSCLC

(2015) Deepak Perumal et al.   Oncotarget

Nicotine Induces Inhibitor of Differentiation-1 in a Src-dependent Pathway Promoting Metastasis and Chemoresistance in Pancreatic Adenocarcinoma

(2015) Jose G. Trevino et al.   NEOPLASIA

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

(2014) Avnish Kapoor et al.   CELL

Nicotine-Mediated Cell Proliferation and Tumor Progression in Smoking-Related Cancers

(2014) Courtney Schaal et al.   MOLECULAR CANCER RESEARCH

NIH Electronic Cigarette Workshop: Developing a Research Agenda

(2014) Kevin M. Walton et al.   NICOTINE & TOBACCO RESEARCH

Nicotine Activates YAP1 through nAChRs Mediated Signaling in Esophageal Squamous Cell Cancer (ESCC)

(2014) Yue Zhao et al.   PLoS One

βArrestin-1 and Mcl-1 Modulate Self-Renewal Growth of Cancer Stem-Like Side-Population Cells in Non-Small Cell Lung Cancer

(2013) Sandeep Singh et al.   PLoS One

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

(2012) Sandeep Singh et al.   Molecular Cancer

Aldehyde dehydrogenase activity is a cancer stem cell marker of tongue squamous cell carcinoma

(2012) BO ZOU et al.   Molecular Medicine Reports

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through α7nAChR-mediated MUC4 upregulation

(2012) N Momi et al.   ONCOGENE

The Hippo signaling pathway and stem cell biology

(2012) Azucena Ramos et al.   TRENDS IN CELL BIOLOGY

ARRB1-Mediated Regulation of E2F Target Genes in Nicotine-Induced Growth of Lung Tumors

(2011) Piyali Dasgupta et al.   JNCI-Journal of the National Cancer Institute

ID1 Facilitates the Growth and Metastasis of Non-Small Cell Lung Cancer in Response to Nicotinic Acetylcholine Receptor and Epidermal Growth Factor Receptor Signaling

(2011) S. Pillai et al.   MOLECULAR AND CELLULAR BIOLOGY

Nicotinic Acetylcholine Receptor Signaling in Tumor Growth and Metastasis

(2011) Sandeep Singh et al.   Journal of Oncology

Proximity ligation assays: a recent addition to the proteomics toolbox

(2010) Irene Weibrecht et al.   Expert Review of Proteomics

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

Cells with Characteristics of Cancer Stem/Progenitor Cells Express the CD133 Antigen in Human Endometrial Tumors

(2009) S. Rutella et al.   CLINICAL CANCER RESEARCH

High Content Screening for Inhibitors of Protein Interactions and Post-translational Modifications in Primary Cells by Proximity Ligation

(2009) Karl-Johan Leuchowius et al.   MOLECULAR & CELLULAR PROTEOMICS

Nicotine Promotes Tumor Growth and Metastasis in Mouse Models of Lung Cancer

(2009) Rebecca Davis et al.   PLoS One

Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines

(2008) Piyali Dasgupta et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer Stem Cells: A Step Toward the Cure

(2008) Bruce M. Boman et al.   JOURNAL OF CLINICAL ONCOLOGY

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

(2008) Ola Söderberg et al.   METHODS

Generation of human induced pluripotent stem cells from dermal fibroblasts

(2008) W. E. Lowry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA