Mechanisms of invasion and motility of high-grade gliomas in the brain

Glioma infiltration and extracellular matrix: key players and modulators

(2018) Valéria Pereira Ferrer et al.   GLIA

Recapitulating in vivo-like plasticity of glioma cell invasion along blood vessels and in astrocyte-rich stroma

(2017) Pavlo Gritsenko et al.   HISTOCHEMISTRY AND CELL BIOLOGY

miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications

(2017) Heather Ames et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Shifting the optimal stiffness for cell migration

(2017) Benjamin L. Bangasser et al.   Nature Communications

Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level

(2017) Rebecca L. Klank et al.   Cell Reports

Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion

(2017) Alison Roos et al.   Frontiers in Oncology

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

The role of CD44 in glioblastoma multiforme

(2016) Kelly L. Mooney et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Mechanical confinement triggers glioma linear migration dependent on formin FHOD3

(2016) Pascale Monzo et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular microenvironment modulates the galvanotaxis of brain tumor initiating cells

(2016) Yu-Ja Huang et al.   Scientific Reports

Differential response of patient-derived primary glioblastoma cells to environmental stiffness

(2016) Thomas James Grundy et al.   Scientific Reports

Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization

(2016) Keiichiro Hayashi et al.   Scientific Reports

Constitutive Activation of Myosin-Dependent Contractility Sensitizes Glioma Tumor-Initiating Cells to Mechanical Inputs and Reduces Tissue Invasion

(2015) S. Y. Wong et al.   CANCER RESEARCH

Non-contact method for directing electrotaxis

(2015) Dinesh K. Ahirwar et al.   Scientific Reports

Engineering strategies to mimic the glioblastoma microenvironment

(2014) Andrew Rape et al.   ADVANCED DRUG DELIVERY REVIEWS

A composite hydrogel platform for the dissection of tumor cell migration at tissue interfaces

(2014) Andrew D. Rape et al.   BIOMATERIALS

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres

(2014) Anjana Jain et al.   NATURE MATERIALS

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

Integrin inhibition promotes atypical anoikis in glioma cells

(2014) M Silginer et al.   Cell Death & Disease

Mechanisms of Glioma Formation: Iterative Perivascular Glioma Growth and Invasion Leads to Tumor Progression, VEGF-Independent Vascularization, and Resistance to Antiangiogenic Therapy

(2014) Gregory J. Baker et al.   NEOPLASIA

The mechanical control of nervous system development

(2013) K. Franze   DEVELOPMENT

Endogenous electric currents might guide rostral migration of neuroblasts

(2013) Lin Cao et al.   EMBO REPORTS

The mechanistic influence of aligned nanofibers on cell shape, migration and blebbing dynamics of glioma cells

(2013) Puja Sharma et al.   Integrative Biology

Expression of the Arp2/3 complex in human gliomas and its role in the migration and invasion of glioma cells

(2013) ZHIFENG LIU et al.   ONCOLOGY REPORTS

Astrocytes Enhance the Invasion Potential of Glioblastoma Stem-Like Cells

(2013) Barbara H. Rath et al.   PLoS One

Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-Dependent Mechanism

(2012) J. M. Munson et al.   CANCER RESEARCH

Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens

(2012) Sanja Ivkovic et al.   MOLECULAR BIOLOGY OF THE CELL

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

PDGF and PDGF receptors in glioma

(2012) Inga Nazarenko et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation

(2011) Carlos Mas-Moruno et al.   Anti-Cancer Agents in Medicinal Chemistry

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Bradykinin Promotes the Chemotactic Invasion of Primary Brain Tumors

(2011) V. Montana et al.   JOURNAL OF NEUROSCIENCE

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells

(2009) Evelyn K.F. Yim et al.   BIOMATERIALS

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Convection-enhanced delivery for the treatment of brain tumors

(2009) Waldemar Debinski et al.   Expert Review of Neurotherapeutics

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Switching direction in electric-signal-induced cell migration by cyclic guanosine monophosphate and phosphatidylinositol signaling

(2009) M. J. Sato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Analysis of Complex Glioma Cell Migration on Electrospun Polycaprolactone Using Time-Lapse Microscopy

(2009) Jed Johnson et al.   TISSUE ENGINEERING PART C-METHODS

The Influence of Test Conditions on Characterization of the Mechanical Properties of Brain Tissue

(2008) M. Hrapko   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

The Role of Myosin II in Glioma Invasion of the Brain

(2008) Christopher Beadle et al.   MOLECULAR BIOLOGY OF THE CELL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE