Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter

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Title
Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter
Authors
Keywords
ABCG2, Multidrug resistance, Cholesterol, Bile acids, Cholesterol recognition amino acid consensus
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Volume 1848, Issue 2, Pages 477-487
Publisher
Elsevier BV
Online
2014-11-17
DOI
10.1016/j.bbamem.2014.11.006

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