Association of ERG/PTEN status with biochemical recurrence after radical prostatectomy for clinically localized prostate cancer

Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012

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Clinical implications of PTEN loss in prostate cancer

(2018) Tamara Jamaspishvili et al.   Nature Reviews Urology

Loss of PTEN expression in ERG-negative prostate cancer predicts secondary therapies and leads to shorter disease-specific survival time after radical prostatectomy

(2016) Kanerva Lahdensuo et al.   MODERN PATHOLOGY

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Current and Proposed Molecular Diagnostics in a Genitourinary Service Line Laboratory at a Tertiary Clinical Institution

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Molecular Pathways: Targeting ETS Gene Fusions in Cancer

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Novel dual-color immunohistochemical methods for detecting ERG–PTEN and ERG–SPINK1 status in prostate carcinoma

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Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer

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Abstract 1752: A phase I/IIa, first time in human, open-label dose-escalation study of GSK2636771 in subjects with advanced solid tumors with PTEN deficiency

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PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade

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Loss of PTEN expression is associated with increased risk of recurrence after prostatectomy for clinically localized prostate cancer

(2012) Alcides Chaux et al.   MODERN PATHOLOGY

Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia

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(2012) Catherine S. Grasso et al.   NATURE

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Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

(2011) J. Chad Brenner et al.   CANCER CELL

Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

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PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer

(2010) Tarek A. Bismar et al.   BJU INTERNATIONAL

Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway

(2009) Todd Morgan et al.   CURRENT CANCER DRUG TARGETS

Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression

(2009) Bo Han et al.   MODERN PATHOLOGY

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

(2009) Jennifer C King et al.   NATURE GENETICS

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

(2009) Brett S Carver et al.   NATURE GENETICS

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

(2009) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer

(2008) R. Mehra et al.   CANCER RESEARCH

Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 Gene Fusions in Prostate Cancer

(2008) B. E. Helgeson et al.   CANCER RESEARCH

Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

(2008) Maisa Yoshimoto et al.   MODERN PATHOLOGY

A causal role for ERG in neoplastic transformation of prostate epithelium

(2008) O. Klezovitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

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PI3K/PTEN signaling in tumorigenesis and angiogenesis

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