Article
Biochemistry & Molecular Biology
K. S. Venkataprasanna, J. Prakash, Santosh S. Mathapati, G. Bharath, Fawzi Banat, G. Devanand Venkatasubbu
Summary: Wound healing is a complex and dynamic process, and research has shown that wound dressing materials with ideal properties can promote different cascades of wound healing. For example, a patch containing Graphene Oxide loaded with vanadium doped titanium dioxide has been found to provide an excellent moist environment for wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biophysics
Huiyan Wang, Jie Li, Han Liang, Xinrong Huang, Na Meng, Ninglin Zhou
Summary: In this study, a method was explored to prepare an effective antibacterial nanocomposite of silver nanoparticles/graphene oxide-sulfobutylether-beta-cyclodextrin (AgNPs/GO-SBE-beta-CD). Dopamine was used as a green and mild reductant to directly reduce silver nitrate on SBE-beta-CD modified graphene oxide. The synthesized nanocomposite showed uniform distribution of silver nanoparticles and exhibited strong antibacterial properties against gram-negative and gram-positive bacteria. It also demonstrated good biocompatibility, making it a promising material for preventing bacterial infection and wound healing applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Jia-Jun Qiu, Ting-Ting Yang, Yi-Fan Li, Wen-Hao Qian, Xuan-Yong Liu
Summary: Au@Ag@Pt core-shell nanorods with noble metal combination were fabricated and assembled on medical titanium surface to investigate their antibacterial activity and biocompatibility. The Pt shell layer on Ti-Au@Ag@Pt was found to slow down the Ag ion release rate, which endowed the medical titanium surface with both antibacterial activity and good biocompatibility without obvious cell toxicity. The antibacterial rates of Ti-Au@Ag@Pt against S. epidermidis and P. aeruginosa were 89.7% and 92.7%, respectively.
Article
Chemistry, Multidisciplinary
Duoduo Gao, Jiachao Xu, Huogen Yu, Yongping Liu, Jiaguo Yu
Summary: A hydroxyl-enriched highly crystalline TiO2 suspensible photocatalyst was synthesized using a simple ethanol-controlled hydrolysis and in situ crystallization method, and exhibited a significantly higher H-2 evolution rate than the well-known commercial P25 TiO2 without any cocatalysts.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Zohaib Razzaq, Awais Khalid, Pervaiz Ahmad, Muhammad Farooq, Mayeen Uddin Khandaker, Abdelmoneim Sulieman, Ibad Ur Rehman, Sohail Shakeel, Ajmal Khan
Summary: Titanium dioxide nanoparticles were synthesized using a hydrothermal method and tested for antibacterial and catalytic properties. They showed the highest antibacterial activity against Gram-negative bacteria and effectively removed the BPB dye through photocatalysis. These properties suggest their potential for environmental remediation applications.
Article
Chemistry, Multidisciplinary
Apisit Karawek, Kittipad Kittipoom, Labhassiree Tansuthepverawongse, Nutkamol Kitjanukit, Wannisa Neamsung, Napat Lertthanaphol, Prowpatchara Chanthara, Sakhon Ratchahat, Poomiwat Phadungbut, Pattaraporn Kim-Lohsoontorn, Sira Srinives
Summary: Photoreduction of carbon dioxide (CO2) to high-value products using a photocatalyst is an effective technique for dealing with CO2 emissions. In this research, TiO2 nanosheets were synthesized using a hydrothermal technique and further composited with graphene oxide and copper oxide to create CTNSG, which exhibited outstanding photoactivity in converting CO2 gas to methane and acetone.
Article
Engineering, Chemical
Guanghui Wang, Jialing Dai, Qiuyan Luo, Nansheng Deng
Summary: A novel TiO2@ACD@RGO composite photocatalyst was successfully synthesized by a photochemical method, displaying high photocatalytic efficiency for the degradation of BPA with a reaction constant of 0.739 mg/L∙min, attributed to improved electron transfer and mass transfer at the interface. The predominant reactive oxygen species for BPA degradation were identified as O-2(-) and h(+). Additionally, the TiO2@ACD@RGO composite exhibited excellent stability and reusability after five cycles.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Agricultural Engineering
Na Zhu, Sijie Zhou, Junyao Gong, Xiaofeng Wang, Chunhua Zhang, Wenbin Li, Dan Sheng, Xin Liu, Liangjun Xia, Weilin Xu
Summary: This study proposes a novel method for rapid in-situ synthesis of Cu2O nanoparticles to develop an antibacterial nanolayer on cotton fiber surface. The antibacterial cotton fabrics exhibit broad-spectrum antibacterial performance against various bacteria, indicating promising potential applications.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Materials Science, Multidisciplinary
Shadpour Mallakpour, Banafsheh Seyfi
Summary: This study aimed to fabricate antibacterial nanocomposite films based on PVA and TiO2-FA nanoparticles. The prepared films exhibited high thermal stability, good UV absorption, low oxygen permeability, and excellent antibacterial properties under UV radiation.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Construction & Building Technology
Abdul Halim Hamdany, Yuanzhao Ding, Shunzhi Qian
Summary: In this study, a graphene oxide-titanium dioxide composite was successfully synthesized through a one-step hydrothermal process, and its structure, morphology, and photocatalytic activity were characterized. The results showed that the synthesized GO-TiO2 composite exhibited efficient photocatalytic inactivation of Escherichia coli under visible light. Furthermore, the composite demonstrated enhanced visible light absorption and a narrowed bandgap, leading to reduced energy requirements for photoexcitation.
JOURNAL OF SUSTAINABLE CEMENT-BASED MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Lina Wang, Peiyi Yan, Huairui Chen, Zhuo Li, Shu Jin, Xiaoxiang Xu, Jun Qian
Summary: The narrow bandgap semiconductor MgIn2S4 has been grown onto In2O3 nanofibers using an in situ growing method. The resulting MgIn2S4-In2O3 hybrid nanofibers exhibit strong visible light absorption and intimate MgIn2S4/In2O3 heterointerfaces, leading to highly efficient photocatalytic disinfection of Escherichia coli.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Article
Chemistry, Physical
Jong Won Lee, Sang Hyuk Lee, Young Il Jang, Hee Mun Park
Summary: The research focused on improving concrete block pavements with added TiO2 to reduce air pollution, and found that the use of NST can enhance the photocatalytic performance of TiO2, leading to a decrease in NO and SO2 concentrations.
Article
Chemistry, Physical
Jia-Hao Shen, Miao-Miao Li, Lian-Feng Chu, Cui-Xiang Guo, Ya-Jun Guo, Ya-Ping Guo
Summary: The study demonstrated that TiO2/rGO composites exhibit excellent photocatalytic activity for the removal of phenol-4-sulfonic acid (PSA) in electroplating wastewater, with Cu2+ ions showing both positive and negative effects on catalytic efficiency. Appropriate concentrations of Cu2+ ions can accelerate the photodegradation of PSA, leading to wastewater purification.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Chanagun Wongburapachart, Phuwadej Pornaroontham, Kyusung Kim, Pramoch Rangsunvigit
Summary: Photocatalysis is an eco-friendly technology that can contribute to achieving the Sustainable Development Goals. However, conventional photocatalysts have limitations such as slow kinetics, limited excitation wavelengths, and environmental restrictions. This study focuses on the development of a photo-chargeable photocatalyst that can operate even in the absence of light, and investigates the effects of synthesis conditions on its photocatalytic properties.
Article
Chemistry, Physical
Agnieszka Wojciechowska, Agata Markowska-Szczupak, Zofia Lendzion-Bielun
Summary: This paper presents a method for synthesizing hybrid magnetic nanomaterials with antibacterial properties, and demonstrates their ability to exist stably under direct solar light based on characterization of their phase composition and crystallite size.
Editorial Material
Biochemical Research Methods
Claude Lambert, Evangelos Ntrivalas, Ulrich Sack
Article
Chemistry, Physical
Silviu Adrian Predoi, Steluta Carmen Ciobanu, Mariana Carmen Chifiriuc, Mikael Motelica-Heino, Daniela Predoi, Simona Liliana Iconaru
Summary: Water contamination is a global problem due to its negative effects on human organisms and the environment. Hydroxyapatite shows potential in decontaminating water by immobilizing pollutants. In this study, synthesized hydroxyapatite was used to remove Sr2+ ions from contaminated solutions. Batch adsorption experiments confirmed the strong affinity of hydroxyapatite nanoparticles for Sr2+ ions. Furthermore, cytotoxic assays showed no harmful effects of hydroxyapatite nanoparticles on HeLa cells.
Article
Biochemistry & Molecular Biology
Gratiela Gradisteanu Pircalabioru, Georgiana Alexandra Grigore, Ilda Czobor Barbu, Mariana-Carmen Chifiriuc, Octavian Savu
Summary: SARS-CoV-2 infection disrupts intestinal microbiota, particularly in patients with type 2 diabetes, leading to more severe disease outcomes. The infection results in changes in the gut microbiome, with an increase in pathogenic bacteria and a decrease in beneficial bacteria. Additionally, certain members of the microbiota are associated with the severity of the disease and inflammatory markers.
Article
Biotechnology & Applied Microbiology
Jin Wen, Zhijun Zhang, Gang Feng, Yang Zhang, Hanzhong Li, Claude Lambert, Nora Mallouk, Guorong Li
Summary: Serum exosomes are commonly used for liquid biopsy. Traditional methods, such as ultracentrifugation, are time-consuming and labor-intensive. Commercial kits using precipitation can lead to contamination. We developed a new method using double precipitation and acetone extraction to isolate pure serum exosomes with typical morphology and sizes ranging from 40 to 150 nm. Flow cytometry confirmed the expression of exosome markers. Our double precipitation method simplifies the detection of serum exosomal biomarkers for disease diagnosis and prognosis.
BIOTECHNIC & HISTOCHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Corneliu Ovidiu Vrancianu, Bogdan Serban, Irina Gheorghe-Barbu, Ilda Czobor Barbu, Roxana Elena Cristian, Mariana Carmen Chifiriuc, Catalin Cirstoiu
Summary: The number of implanted prosthetic joints is increasing due to longer life spans and increased mobility in older individuals. Unfortunately, the number of periprosthetic joint infections (PJIs), a severe complication after joint replacement surgery, is also on the rise. Efficient protocols for managing these infections can lead to preventive measures and effective diagnostic methods using laboratory tests. This review discusses current methods for PJI diagnosis and emerging synovial biomarkers used for prognosis, prophylaxis, and early detection of periprosthetic infections, as well as factors contributing to treatment failure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Ilda Czobor Barbu, Irina Gheorghe-Barbu, Georgiana Alexandra Grigore, Corneliu Ovidiu Vrancianu, Mariana Carmen Chifiriuc
Summary: This article provides an overview of the antibiotic resistance profiles and epidemiology of multidrug-resistant Gram-negative bacteria circulating in Romania, including Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacterales strains. The study highlights the urgent need for therapeutic strategies against these pathogens, as they pose a global threat and have established resistance genes in different geographical areas of Romania.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Pharmacology & Pharmacy
Gabriela Dorcioman, Valentina Grumezescu, George E. Stan, Mariana Carmen Chifiriuc, Gratiela Pircalabioru Gradisteanu, Florin Miculescu, Elena Matei, Gianina Popescu-Pelin, Irina Zgura, Valentin Craciun, Faik Nuzhet Oktar, Liviu Duta
Summary: Novel biomaterials with excellent bone regeneration potential were synthesized from marine-derived hydroxyapatite by pulsed laser deposition. The rough surfaces of the thin films promoted cell adhesion and implant anchorage. The thin films exhibited strong hydrophilic behavior, superior bonding strength adherence, low cytotoxicity, and effective antimicrobial activity. These cost-effective materials from sustainable sources are recommended for the development of innovative coatings for metallic dental implants.
Article
Pharmacology & Pharmacy
Gabriela Marinescu, Daniela C. Culita, Teodora Mocanu, Raul-Augustin Mitran, Simona Petrescu, Miruna S. Stan, Mariana C. Chifiriuc, Marcela Popa
Summary: A series of nanostructured materials were obtained by functionalizing SBA-15 mesoporous silica with Ru(II) and Ru(III) complexes bearing Schiff base ligands. The resulting materials showed antitumoral activity against lung tumor cells and inhibitory effects against bacteria.
Article
Biochemistry & Molecular Biology
Alexandru Bujor, Anamaria Hanganu, Victorita Tecuceanu, Augustin M. Madalan, Madalina Tudose, Luminita Marutescu, Marcela Popa, Carmen Mariana Chifiriuc, Irina Zarafu, Petre Ionita
Summary: 4-Aminodiphenylamino derivatives were studied for their antioxidant and hydrophobic properties, as well as their antimicrobial and antibiofilm activity. Novel derivatives were obtained by reacting the starting material with NBD-chloride. A comprehensive structural analysis was conducted using various techniques, and the hydrophobicity of the compounds was measured experimentally or calculated. The results showed a correlation between the experimental and computed properties. Additionally, some of the synthesized compounds exhibited antimicrobial and antibiofilm activity.
Article
Infectious Diseases
Roxana Roman, Lucia Pintilie, Miron Teodor Caproiu, Florea Dumitrascu, Diana Camelia Nuta, Irina Zarafu, Petre Ionita, Mariana Carmen Chifiriuc, Cornel Chirita, Alina Morosan, Marcela Popa, Coralia Bleotu, Carmen Limban
Summary: New N-acyl thiourea derivatives with heterocyclic rings were synthesized and characterized. In vitro tests showed antibiofilm and antioxidant activities for compound 1d. A RP-HPLC method was optimized for quantitative determination of compound 1d. The promising potential of these derivatives will be further investigated for drug development.
Article
Infectious Diseases
Ioana Cristina Marinas, Eliza Oprea, Diana Madalina Gaboreanu, Gratiela Gradisteanu Pircalabioru, Mihaela Buleandra, Eugenia Nagoda, Irinel Adriana Badea, Mariana Carmen Chifiriuc
Summary: The essential oil of Achillea setacea was extracted and characterized by GC-MS. Its antioxidant and antimicrobial activity were evaluated, as well as its biocompatibility. The oil showed antimicrobial effects against various important microbial strains and demonstrated potential applications beyond the clinical field.
Article
Biochemical Research Methods
Louis Waeckel, Hana Khenine, Anne-Emmanuelle Berger, Claude Lambert
Summary: Multiple immunolabeling can lead to interference between different fluorescences. In this study, a fluorescence resonance energy transfer (FRET) effect was observed between PB and FITC, resulting in a signal on the V550 detector. This interference is caused by the partial overlap of the emission and excitation spectra of PB and FITC.
Article
Environmental Sciences
Ionela C. Voinea, Cristina F. Alistar, Alina Banciu, Roua G. Popescu, Sorina N. Voicu, Mihai Nita-Lazar, Gabriela Geanina Vasile, Stefania Gheorghe, Alexa -Maria Croitoru, Georgiana Dolete, Dan Eduard Mihaiescu, Anton Ficai, Marcela Popa, Luminita Marutescu, Gratiela Gradisteanu Pircalabioru, Nicolae Craciun, Sorin Avramescu, George Catalin Marinescu, Mariana-Carmen Chifiriuc, Miruna S. Stan, Anca Dinischiotu
Summary: In recent decades, increased contamination intake and habitat destruction have caused significant changes in aquatic ecosystems. The accumulation of environmental contaminants in aquatic organisms has disrupted the antioxidant/prooxidant balance in fish. This study evaluated the levels of organic, inorganic, and microbiological pollutants in four leisure lakes in Bucharest, Romania, to compare their impact on hepatopancreas and gill metabolism and antioxidant defense.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Materials Science, Multidisciplinary
Dana Gingasu, Daniela C. C. Culita, Jose Maria Calderon Moreno, Gabriela Marinescu, Cristina Bartha, Ovidiu Oprea, Silviu Preda, Mariana Carmen Chifiriuc, Marcela Popa
Summary: This study investigated a new method called wet ferritization to produce magnetic cobalt ferrite (CoFe2O4) using eucalyptus leaves aqueous extract. The prepared samples showed single cubic phases of cobalt ferrite confirmed by various analysis techniques. The biosynthesized CoFe2O4 showed potential for biomedical applications with antimicrobial and antibiofilm activity against Gram-negative bacteria and fungal strains.
Article
Biochemistry & Molecular Biology
Irina Negut, Gratiela Gradisteanu-Pircalabioru, Mihaela Dinu, Bogdan Bita, Anca Constantina Parau, Valentina Grumezescu, Carmen Ristoscu, Mariana Carmen Chifiriuc
Summary: This study reports the use of MAPLE synthesized thin films based on BG and VD3 to enhance osseointegration and corrosion protection of Ti-like implant surfaces. The results show that the films have good chemical stability and biocompatibility, with favorable cell adhesion and no inflammatory response. The films also demonstrate good wettability, facilitating interaction with biological fluids.
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
