A High-Content Screening Assay for the Discovery of Novel Proteasome Inhibitors from Formosan Soft Corals

Marine natural products

(2018) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Host-microbe interactions in octocoral holobionts - recent advances and perspectives

(2018) Jeroen A. J. M. van de Water et al.   Microbiome

Ecosystem Microbiology of Coral Reefs: Linking Genomic, Metabolomic, and Biogeochemical Dynamics from Animal Symbioses to Reefscape Processes

(2018) Linda Wegley Kelly et al.   mSystems

Hsp70 - a master regulator in protein degradation

(2017) María Rosario Fernández-Fernández et al.   FEBS LETTERS

Structural characterization of the bacterial proteasome homolog BPH reveals a tetradecameric double-ring complex with unique inner cavity properties

(2017) Adrian C. D. Fuchs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome Structure and Assembly

(2017) Lauren Budenholzer et al.   JOURNAL OF MOLECULAR BIOLOGY

The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System

(2017) Adrian C.D. Fuchs et al.   STRUCTURE

Metabolomics of reef benthic interactions reveals a bioactive lipid involved in coral defence

(2016) Robert A. Quinn et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism

(2016) Tal Keren-Kaplan et al.   Nature Communications

Rpn10 monoubiquitination orchestrates the association of the ubiquilin-type DSK2 receptor with the proteasome

(2015) A. Zuin et al.   BIOCHEMICAL JOURNAL

Evolution of Proteasome Regulators in Eukaryotes

(2015) Philippe Fort et al.   Genome Biology and Evolution

Anti-Protozoal Activities of Cembrane-Type Diterpenes from Vietnamese Soft Corals

(2015) Nguyen Thao et al.   MOLECULES

Ubiquitination in disease pathogenesis and treatment

(2014) Doris Popovic et al.   NATURE MEDICINE

Regulation of proteasome activity in health and disease

(2013) Marion Schmidt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Novel Bullet Hits the Proteasome

(2013) Alexei F. Kisselev   CANCER CELL

Human Cytomegalovirus UL76 Elicits Novel Aggresome Formation via Interaction with S5a of the Ubiquitin Proteasome System

(2013) S.-R. Lin et al.   JOURNAL OF VIROLOGY

A Defined Methodology for Reliable Quantification of Western Blot Data

(2013) Sean C. Taylor et al.   MOLECULAR BIOTECHNOLOGY

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

Alterations of the Intracellular Peptidome in Response to the Proteasome Inhibitor Bortezomib

(2013) Julia S. Gelman et al.   PLoS One

Soft Coral Sarcophyton (Cnidaria: Anthozoa: Octocorallia) Species Diversity and Chemotypes

(2012) Satoe Aratake et al.   PLoS One

Cytotoxic and anti-inflammatory cembranoids from the Vietnamese soft coral Lobophytum laevigatum

(2011) Tran Hong Quang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors

(2011) Hossam M. Hassan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events

(2011) S. Arastu-Kapur et al.   CLINICAL CANCER RESEARCH

Cembranoids from the OctocoralSarcophyton ehrenbergi

(2010) Shi-Yie Cheng et al.   JOURNAL OF NATURAL PRODUCTS

Monoubiquitination of RPN10 Regulates Substrate Recruitment to the Proteasome

(2010) Marta Isasa et al.   MOLECULAR CELL

New Cembranoid Diterpenes from the Vietnamese Soft Coral Sarcophyton mililatensis Stimulate Osteoblastic Differentiation in MC3T3-E1 Cells

(2008) Nguyen Xuan Cuong et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY