Article
Chemistry, Applied
Kentaro Shoji, Aoi Kameda, Kayo Furuichi
Summary: Amazakes made from rice and koji mold are rich in nutrients and can improve skin moisturization. This study investigated the effect of milk amazake on skin function through a double-blind, randomized controlled trial. The results suggest that milk amazake may be useful as a functional food for improving skin function.
JOURNAL OF OLEO SCIENCE
(2023)
Article
Engineering, Biomedical
Akihito Miyamoto, Hiroshi Kawasaki, Sunghoon Lee, Tomoyuki Yokota, Masayuki Amagai, Takao Someya
Summary: A method is reported for continuous monitoring of skin electrical resistance and transepidermal water loss, which can evaluate the barrier function of the skin and reflect the dynamic changes of skin physiology.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Medicine, General & Internal
Trinidad Montero-Vilchez, Juan-Angel Rodriguez-Pozo, Pablo Diaz-Calvillo, Maria Salazar-Nievas, Jesus Tercedor-Sanchez, Alejandro Molina-Leyva, Salvador Arias-Santiago
Summary: The study aimed to evaluate the impact of dupilumab on skin barrier function in patients with atopic dermatitis (AD) and compare it with other treatments. The study found that dupilumab was more effective in improving barrier function in both eczematous lesions and non-lesioned skin compared to topical corticosteroids and cyclosporine.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Medicinal
Masaki Honda, Hakuto Kageyama, Yelin Zhang, Takashi Hibino, Motonobu Goto
Summary: This study investigated the effect of oral supplementation with Astaxanthin on UV light-induced skin damage in guinea pigs. The results showed that Astaxanthin accumulates in the skin and prevents UV light-induced skin damage. The Z-isomers of Astaxanthin showed better skin-protective ability and reduced skin pigmentation caused by Astaxanthin accumulation compared to the all-E-isomer.
Article
Medicine, General & Internal
Trinidad Montero-Vilchez, Maria-Victoria Segura-Fernandez-Nogueras, Isabel Perez-Rodriguez, Miguel Soler-Gongora, Antonio Martinez-Lopez, Ana Fernandez-Gonzalez, Alejandro Molina-Leyva, Salvador Arias-Santiago
Summary: This study compared skin barrier function between healthy skin, psoriatic skin, and atopic dermatitis skin, finding that TEWL was higher at psoriatic and AD lesions, while SCH was lower. Specific TEWL and temperature values may help clinicians determine disease severity and treatment needs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Food Science & Technology
Xiaocao Zhao, Xuejiao Zhang, Dengyong Liu
Summary: Bioactive peptides, particularly collagen peptides, have great potential in skin anti-aging due to their diverse biological activities and high security. These peptides can provide skin protection effects by affecting various physiological pathways of the skin, thereby improving skin health.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Biochemistry & Molecular Biology
Aneta Prokopova, Jana Pavlackova, Pavel Mokrejs, Robert Gal
Summary: The study showed that a cosmetic gel formulation enriched with chicken collagen hydrolysate can significantly improve skin hydration, elasticity, and wrinkles in the periorbital area. The longer the formulation is applied, the better the results, benefiting from the biocompatibility and biodegradability of the product.
Article
Dermatology
Trinidad Montero-Vilchez, Antonio Martinez-Lopez, Carlos Cuenca-Barrales, Andrea Rodriguez-Tejero, Alejandro Molina-Leyva, Salvador Arias-Santiago
Summary: Wearing masks and gloves may impair skin homeostasis and epidermal barrier function, leading to increased transepidermal water loss and higher skin temperature. High-quality personal protective equipment should be provided, and appropriate skin prevention measures should be implemented.
Article
Multidisciplinary Sciences
Lars Ruether, Werner Voss
Summary: Five different galenics were analyzed for tissue breathability and gas exchange after 6 hours of application on pig ear skin. Hydrogel preparations showed higher breathability and moisture penetration, while Tyrosur (R) Care Expert Wound Gel and ointment exhibited sustained moisturizing effects.
Article
Dermatology
Eunyoung Lee, Changhui Cho, Jaehyoun Ha
Summary: Facial skin redness can have a negative impact on quality of life, especially for women over 40 who tend to perceive it less. Redness-prone women had higher intensity of redness and skin surface perfusion, lower skin hydration, and weaker skin properties as they aged. The study's findings provide insight into age-related biophysical characteristics of non-pathological facial skin redness and may help mitigate its negative effects.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Veterinary Sciences
Adrien Idee, Marion Mosca, Didier Pin
Summary: This study evaluated the effect of a spot-on containing fatty acids, ceramides, and essential oils on the skin barrier function of dogs. The results showed that the spot-on had a protective effect on the skin barrier function. This suggests that the investigated product may be useful as an adjunctive treatment for canine atopic dermatitis.
VETERINARY SCIENCES
(2022)
Article
Peripheral Vascular Disease
Takahiro Ogura, Kento Kitada, Norihiko Morisawa, Yoshihide Fujisawa, Satoshi Kidoguchi, Daisuke Nakano, Hideki Kobara, Tsutomu Masaki, Jens Titze, Akira Nishiyama
Summary: This study investigated the pathogenesis of hypertension in spontaneously hypertensive rats and identified renal concentration ability and skin barrier function for water conservation as potential therapeutic targets for essential hypertension.
HYPERTENSION RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Jutarat Kitsongsermthon, Natcha Kumboonlert, Naowarat Saksumolrat
Summary: The study developed a dissolving microneedle array composed of sodium hyaluronate and polyvinyl alcohol, which had a moisturizing effect on the skin, increasing skin hydration and reducing transepidermal water loss.
JOURNAL OF PHARMACEUTICAL INVESTIGATION
(2021)
Article
Biochemistry & Molecular Biology
Larry Galan-Navea, Rocio Guerle-Cavero, Albert Balfagon-Costa, Beatriz Artalejo-Ortega
Summary: This article aims to study the physical model of skin made from collagen, chitosan or their combination as biomaterial scaffold, and investigate whether they exhibit similar properties to human skin. The results show that the tri-layered membranes perform better than mono-layered ones in terms of elastic modulus and permeability, and provide better protection against water loss. Moreover, chitosan membranes have a higher elastic modulus than collagen membranes when the degree of deacetylation is 85%, while collagen membranes are more elastic when the chitosan degree of acetylation is 76%.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Kyoungmi Jung, Seung-Hun Kim, Kyung-Mi Joo, Sung-Hwan Lim, Jin-Hee Shin, Jonghwa Roh, Eunjoo Kim, Chan Woong Park, Wangi Kim
Summary: Oral intake of enzymatically decomposed AP collagen peptides can improve skin moisture, enhance the skin barrier function, and increase the levels of ceramide and natural moisturizing factor in the stratum corneum.
Article
Neurosciences
Naoki Ito, Hitomi Saito, Shinobu Seki, Fumitaka Ueda, Takashi Asada
JOURNAL OF ALZHEIMERS DISEASE
(2018)
Article
Nutrition & Dietetics
Ayano Imai, Yuriko Oda, Naoki Ito, Shinobu Seki, Kiyotaka Nakagawa, Teruo Miyazawa, Fumitaka Ueda
Article
Nutrition & Dietetics
Naoki Ito, Shinobu Seki, Fumitaka Ueda
Correction
Multidisciplinary Sciences
Naoki Ito, Isao Kii, Noriaki Shimizu, Hirotoshi Tanaka, Shin'ichi Takeda
SCIENTIFIC REPORTS
(2018)
Correction
Multidisciplinary Sciences
Naoki Ito, Isao Kii, Noriaki Shimizu, Hirotoshi Tanaka, Shin'ichi Takeda
SCIENTIFIC REPORTS
(2018)
Article
Biochemistry & Molecular Biology
Jun Tanihata, Tetsuya Nagata, Naoki Ito, Takashi Saito, Akinori Nakamura, Susumu Minamisawa, Yoshitsugu Aoki, Urs T. Ruegg, Shin'ichi Takeda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2018)
Article
Biochemistry & Molecular Biology
Naoki Ito, Urs T. Ruegg, Shin'ichi Takeda
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2018)
Article
Biochemistry & Molecular Biology
Naoki Ito, Yuko Miyagoe-Suzuki, Shin'ichi Takeda, Akira Kudo
Summary: In this study, the protective role of periostin, a matricellular protein, in skeletal muscle regeneration was identified. Periostin-null mice showed decreased muscle weight due to the loss of muscle fibers during repeated muscle regeneration. The decrease in CD31-positive blood vessels during muscle regeneration in periostin-null mice suggests that the decreased nutritional supply may be the cause of muscle fiber loss.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Risa Okada, Shin-ichiro Fujita, Riku Suzuki, Takuto Hayashi, Hirona Tsubouchi, Chihiro Kato, Shunya Sadaki, Maho Kanai, Sayaka Fuseya, Yuri Inoue, Hyojung Jeon, Michito Hamada, Akihiro Kuno, Akiko Ishii, Akira Tamaoka, Jun Tanihata, Naoki Ito, Dai Shiba, Masaki Shirakawa, Masafumi Muratani, Takashi Kudo, Satoru Takahashi
Summary: This study found that exposure to artificial 1 g environment prevented the effects of microgravity on the soleus muscle, both in terms of muscle mass and fiber type composition, as well as gene expression profiles. The potential role of Cacng1 in myotube atrophy was suggested, and further research on novel candidate genes may help elucidate the mechanism of muscle atrophy.
SCIENTIFIC REPORTS
(2021)
Article
Cell Biology
Haruko Watanabe-Takano, Hiroki Ochi, Ayano Chiba, Ayaka Matsuo, Yugo Kanai, Shigetomo Fukuhara, Naoki Ito, Keisuke Sako, Takahiro Miyazaki, Kazuki Tainaka, Ichiro Harada, Shingo Sato, Yasuhiro Sawada, Naoto Minamino, Shu Takeda, Hiroki R. Ueda, Akihiro Yasoda, Naoki Mochizuki
Summary: This study identified OSTN as a mechanotransducer for load-induced long bone growth, enhancing CNP-dependent proliferation and maturation of chondrocytes. OSTN cooperates with CNP to regulate bone formation, preventing NPR3-mediated clearance of CNP and facilitating CNP-signal-mediated bone growth.
Article
Oncology
So-ichiro Fukada, Naoki Ito
Summary: Skeletal muscles have plasticity and can adapt to mechanical load induced by physical activity by increasing myofiber size and myonuclear number. Protein synthesis and MuSCs play important roles in this process. However, the signaling pathways promoting protein synthesis and the necessity of MuSCs in muscle hypertrophy are still controversial issues.
EXPERIMENTAL CELL RESEARCH
(2021)
Article
Cell Biology
Naoki Ito, Ai Takatsu, Hiromi Ito, Yuka Koike, Kiyoshi Yoshioka, Yasutomi Kamei, Shin-ichiro Imai
Summary: This study demonstrates the functional connection between the lateral hypothalamus and skeletal muscle through the transporter Slc12a8. The knockdown of Slc12a8 in the lateral hypothalamus leads to decreased skeletal muscle functions, while overexpression ameliorates age-associated decreases in energy expenditure and skeletal muscle functions.
Correction
Neurosciences
Naoki Ito, Hitomi Saito, Shinobu Seki, Fumitaka Ueda, Takashi Asada
JOURNAL OF ALZHEIMERS DISEASE
(2019)
Correction
Clinical Neurology
Yoshitsugu Aoki, Raquel Manzano, Yi Lee, Ruxandra Dafinca, Misako Aoki, Andrew G. L. Douglas, Miguel A. Varela, Chaitra Sathyaprakash, Jakub Scaber, Paola Barbagallo, Pieter Vader, Imre Mager, Kariem Ezzat, Martin R. Turner, Naoki Ito, Samanta Gasco, Norihiko Ohbayashi, Samir El Andaloussi, Shin'ichi Takeda, Mitsunori Fukuda, Kevin Talbot, Matthew J. A. Wood