Article
Clinical Neurology
Assaf Berger, Juan Diego Alzate, Kenneth Bernstein, Reed Mullen, Sean McMenomey, Daniel Jethanemest, David R. Friedmann, Eric Smouha, Erik P. Sulman, Joshua S. Silverman, J. Thomas Roland, John G. Golfinos, Douglas Kondziolka
Summary: This study evaluates hearing outcomes in patients with vestibular schwannoma (VS) during the modern era of cochlear dose restriction. The results show that factors such as age, baseline GR score, cochlear dose, and biological effective dose are correlated with hearing preservation. Increased tumor-free canal space is associated with better outcomes. Furthermore, patients who meet specific criteria have higher hearing preservation rates compared to the rest of the population.
Review
Medicine, General & Internal
Makoto Hosoya, Takeshi Wakabayashi, Koichiro Wasano, Takanori Nishiyama, Nobuyoshi Tsuzuki, Naoki Oishi
Summary: This article reviews recent advances in the management and treatment of vestibular schwannoma, particularly in hearing preservation. By improving intraoperative monitoring systems and conducting precise genomic analysis, the treatment of vestibular schwannomas is expected to be improved.
Article
Otorhinolaryngology
Yavor Bozhkov, Julia Shawarba, Julian Feulner, Fabian Winter, Stefan Rampp, Ullrich Hoppe, Arnd Doerfler, Heinrich Iro, Michael Buchfelder, Karl Roessler
Summary: Surgery for small vestibular schwannomas can achieve excellent hearing preservation. Different grading systems have a significant impact on and correlate with postoperative hearing preservation. Tumor size appears to be more important than anatomical relationships.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Article
Clinical Neurology
Omid Moshtaghi, Peter R. Dixon, Alexander D. Claussen, Olivia La Monte, Ashley Tadano, Dominique Gillette, Kareem Tawfik, Marc S. Schwartz, Rick A. Friedman
Summary: This retrospective study aimed to evaluate the differences in postoperative hearing in patients who underwent immediate versus delayed microsurgical resection of vestibular schwannomas (VS). The results showed that patients who underwent early surgery had a higher hearing preservation rate compared to those who had delayed surgery.
OTOLOGY & NEUROTOLOGY
(2023)
Article
Medicine, General & Internal
Makoto Hosoya, Takanori Nishiyama, Takeshi Wakabayashi, Marie N. Shimanuki, Hidemi Miyazaki, Hiroyuki Ozawa, Naoki Oishi
Summary: Surgery for vestibular schwannoma can be performed using different techniques, including the middle cranial fossa, suboccipital, translabyrinthine, and retrolabyrinthine approaches. The retrolabyrinthine approach, which preserves the labyrinth, has been modified to achieve a higher hearing preservation rate of 79% in our department. This improvement is considered helpful for hearing preservation.
Article
Medicine, Research & Experimental
Douglas M. M. Hildrew, Philip L. L. Perez, Leila J. J. Mady, Jinhong Li, Marci L. L. Nilsen, Barry E. E. Hirsch
Summary: The objective of this study was to determine tumor control rates and hearing outcomes for treating growing vestibular schwannoma (VS) with CyberKnife stereotactic radiosurgery (CK SRS) and propose a predictive model for hearing outcomes. A retrospective case series review was conducted on 127 patients who received CK SRS for growing VS. The tumor control rate was 94.5% and hearing preservation was achieved in a third of patients. The final predictive model included variables such as age, fundal cap distance (FCD), tumor volume, and maximum radiation dose to the cochlea.
Article
Otorhinolaryngology
Yin Ren, Kareem O. Tawfik, Bill J. Mastrodimos, Roberto A. Cueva
Summary: Radiographic predictors such as tumor size and extension relative to the internal auditory canal play a significant role in hearing preservation after retrosigmoid resection of vestibular schwannomas. Patients with small intracanalicular tumors and good preoperative hearing have the highest rates of hearing preservation, while tumors extending into the cerebellopontine angle may have worse outcomes if they have greater posterior and caudal extension relative to the internal auditory canal.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Review
Clinical Neurology
Vera Ong, Ashley B. Zhang, Bayard Wilson, Nolan J. Brown, Brian V. Lien, Shane Shahrestani, Isaac Yang
Summary: This study provides a bibliometric analysis of hearing preservation in treating vestibular schwannomas, revealing a lack of prospective studies and novel treatment options in the current literature.
WORLD NEUROSURGERY
(2022)
Article
Oncology
Zhenxing Yang, Xiaoxing Xiong, Zhihong Jian, Li Du
Summary: This study investigated the effects of endoscopic-assisted microsurgery technique on the resection of large vestibular schwannoma and analyzed the prognosis of patients. The results showed that all tumors were completely removed in 16 cases and the facial nerve was anatomically preserved in 14 cases. The use of endoscopic-assisted microsurgery technique provides a wider surgical field, reduces complications, and ensures complete removal of internal auditory canal tumors.
FRONTIERS IN ONCOLOGY
(2023)
Article
Clinical Neurology
Steven D. Chang, Alexander Muacevic, Andrea L. Klein, Jonathan H. Sherman, Pantaleo Romanelli, Peter L. Santa Maria, Christoph Fuerweger, Isa Bossi Zanetti, Giancarlo Beltramo, Yona Vaisbush, Emma Tran, Austin Feng, Hao Teng, Antonio Meola, Iris Gibbs, Antony M. Tolisano, Joe Walter Kutz Jr, Zabi Wardak, Lucien A. Nedzi, Robert Hong, Don MacRae, Preet Sohal, Elina Kapoor, Parisa Sabet-Rasekh, Sam Maghami, Paola X. Moncada, Ashley Zaleski-King, Richard Amdur, Ashkan Monfared
Summary: A multicenter retrospective analysis of 611 patients who underwent SRS for VS from 1990-2020 found that decline of hearing in the treated ears was directly related to maximum cochlear dose, single versus 3-fraction treatment, total tumor radiation dose, and baseline hearing level. The maximum safe cochlear dose for hearing preservation at one year is 3 Gy, and the use of 3 fractions instead of one fraction was better at preserving hearing.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Ricardo Ramina, Gustavo S. Jung, Felipe Constanzo, Erasmo Barros da Silva Jr
Summary: The study aimed to evaluate the effect of nerve position within the internal auditory canal on preoperative and postoperative cochlear and facial nerve function in patients with intracanalicular vestibular schwannoma. The study found that patients with tumors located between the vestibular and facial-cochlear nerves had worse outcomes in terms of facial nerve function and hearing preservation after surgery.
JOURNAL OF NEUROSURGERY
(2023)
Article
Medicine, Research & Experimental
Christian Scheller, Christian Strauss, Sandra Leisz, Pia Hanel, Ariane Klemm, Simone Kowoll, Iris Boselt, Torsten Rahne, Andreas Wienke
Summary: The study investigated the efficacy and safety of prophylactic nimodipine treatment for hearing preservation in vestibular schwannoma surgery, with potential positive effects on hearing and potential recommendation for routine medication in the future.
Article
Oncology
Isabel Gugel, Florian Grimm, Philip Hartjen, Maria Breun, Julian Zipfel, Marina Liebsch, Hubert Lowenheim, Ulrike Ernemann, Lan Kluwe, Victor-Felix Mautner, Marcos Tatagiba, Martin Ulrich Schuhmann
Summary: Both BAEP and audiometry are essential in the decision-making process for neuro-oncological treatment of NF2-associated VS, with preoperative BAEP and resection amount significantly influencing postoperative hearing outcome. A prediction model indicates that an increase in BAEP class is associated with an increased risk of postoperative hearing deterioration. Larger resection amounts pose a higher risk compared to smaller resections, emphasizing the importance of careful monitoring and adjustment during surgery.
Article
Clinical Neurology
Luciano Mastronardi, Alberto Campione, Guglielmo Cacciotti, Ettore Carpineta, Carlo Giacobbo Scavo, Raffaele Roperto, Giovanni Stati, Albert A. Sufianov, Karl Schaller
Summary: Microsurgery of vestibular schwannoma in patients aged 40 or less is associated with good functional results and high rates of total or near-total tumor removal. Patients under 30 years of age tend to have larger, more hypervascularized tumors with more bleeding during surgery and worse long-term functional outcomes compared to those in their fourth decade of life. Limited experience suggests that near-total resection should be preferred for very young patients with large, adherent, hypervascularized tumors to maximize resection and preserve function.
NEUROSURGICAL REVIEW
(2022)
Article
Clinical Neurology
Daniele Starnoni, Giulia Cossu, Rodolfo Maduri, Constantin Tuleasca, Mercy George, Raphael Maire, Mahmoud Messerer, Marc Levivier, Etienne Pralong, Roy T. Daniel
Summary: Direct electrical stimulation and recording of postauricular muscle response (PAMR) can be used to preserve cochlear nerve and hearing during surgery. Stimulation parameters of 1mA at 1Hz were found to induce cochlear response without affecting other nerves. Most patients maintained stable hearing during the surgery, with some even experiencing significant improvement.
JOURNAL OF NEUROSURGERY
(2023)
