Mitochondrial pyruvate carrier 1 functions as a tumor suppressor and predicts the prognosis of human renal cell carcinoma

Hypoxia-inducible factor-1α: a promising therapeutic target for autoimmune diseases

(2017) Shi-Yang Guan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma

(2017) Ali Mehdi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lactate dehydrogenase activity drives hair follicle stem cell activation

(2017) Aimee Flores et al.   NATURE CELL BIOLOGY

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism

(2017) John C. Schell et al.   NATURE CELL BIOLOGY

MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer

(2016) Xiaoli Li et al.   BMC CANCER

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

(2016) Roman Camarda et al.   NATURE MEDICINE

Recent advances in renal cell carcinoma from a pathological point of view

(2016) Shuji Mikami et al.   PATHOLOGY INTERNATIONAL

Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells

(2016) Pengying Li et al.   Scientific Reports

Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA

(2015) An S. Tan et al.   Cell Metabolism

Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes

(2015) T. Bender et al.   EMBO JOURNAL

Hypoxia-induced overexpression of stanniocalcin-1 is associated with the metastasis of early stage clear cell renal cell carcinoma

(2015) Xin Ma et al.   Journal of Translational Medicine

Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect

(2015) Vincent Compan et al.   MOLECULAR CELL

A comparative immunological analysis of CoCl2 treated cells with in vitro hypoxic exposure

(2014) Shweta et al.   BIOMETALS

Hypoxia-Induced SUMOylation of E3 Ligase HAF Determines Specific Activation of HIF2 in Clear-Cell Renal Cell Carcinoma

(2014) M. Y. Koh et al.   CANCER RESEARCH

The role of HIF1α in renal cell carcinoma tumorigenesis

(2014) Lorraine J. Gudas et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth

(2014) John C. Schell et al.   MOLECULAR CELL

Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport

(2014) Chendong Yang et al.   MOLECULAR CELL

Profiling metabolic networks to study cancer metabolism

(2012) Karsten Hiller et al.   CURRENT OPINION IN BIOTECHNOLOGY

Identification and Functional Expression of the Mitochondrial Pyruvate Carrier

(2012) S. Herzig et al.   SCIENCE

A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans

(2012) D. K. Bricker et al.   SCIENCE

The changing pattern of kidney cancer incidence and mortality in Europe

(2008) Fabio Levi et al.   BJU INTERNATIONAL

Targeting the Mitochondria for Cancer Therapy: Regulation of Hypoxia-Inducible Factor by Mitochondria

(2007) Eric L. Bell et al.   ANTIOXIDANTS & REDOX SIGNALING