Review
Neurosciences
Patryk A. Musko, Andreas K. Demetriades
Summary: Female athletes are more susceptible to sport-related concussions, especially in soccer. They experience more somatic symptoms such as headache, migraine, and sleep disturbance, and may require longer recovery time. The 6th ICSS does not extensively address sex differences, which are crucial for concussion management protocols in many sports.
Article
Psychology, Developmental
Catherine C. McDonald, Divya Jain, Eileen P. Storey, Madeline Gonzalez, Christina L. Master, Kristy B. Arbogast
Summary: The study found that many adolescents continued to drive after concussion, despite not yet having returned to exercise or sport; the majority of adolescents were advised to gradually increase cognitive activity after clinical assessment, suggesting a gradual increase in driving may be justified.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Article
Clinical Neurology
Grant L. Iverson, Justin E. Karr
Summary: Previous research has found a significant association between sustaining a concussion and suicidality in adolescents. However, this study found that after controlling for other relevant variables, there was no significant association between concussion and suicidality, except for a significant relationship between concussion and suicide attempts in boys.
FRONTIERS IN NEUROLOGY
(2022)
Article
Engineering, Biomedical
Enora Le Flao, Seth Lenetsky, Gunter P. Siegmund, Robert Borotkanics
Summary: This study compares the number of head acceleration events recorded by three wearable sensors during boxing and assesses the impact of type and location on triggering acceleration events. The results show that all three sensors have different levels of sensitivity and specificity, but their positive predictive value for head impacts exceeds 96%. All three sensors are more likely to be triggered by clean punches landing near the sensor. The sensitivity of the mouthguard to impact location is relatively stable compared to the patches.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Review
Sport Sciences
Laura A. M. Dunne, Michael H. Cole, Stuart J. Cormack, David R. Howell, Rich D. Johnston
Summary: This systematic review examines the reliability, validity, and feasibility of motor function assessments in the management of sports-related concussion. The findings suggest that instrumented, gait-based assessments are preferable over static or dynamic assessments. Although laboratory equipment shows sufficient reliability and validity, they demonstrate poor feasibility. Further research on more readily available devices is needed to improve current concussion management protocols.
SPORTS MEDICINE-OPEN
(2023)
Article
Critical Care Medicine
Pora Kuperman, Yelena Granovsky, Shiri Fadel, Noam Bosak, Chen Buxbaum, Rafi Hadad, Elliot Sprecher, Hany Bahouth, Hen Ben Lulu, David Yarnitsky, Michal Granot
Summary: This study aimed to explore the role of pain and post-traumatic psychological features in explaining head and neck-related symptom variability in post-collision patients. While there is a common explanatory feature between neck- and head-related symptoms, they are not entirely overlapping.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Clinical Neurology
Grant L. Iverson, Jonathan Greenberg, Nathan E. Cook
Summary: Pre-injury and post-injury anxiety are prevalent among adolescents and young adults with concussions, and are important risk factors for persistent post-concussion symptoms. Elevated post-injury anxiety was found to be the strongest predictor of ongoing symptoms, highlighting the need for assessment and treatment of anxiety in this population.
FRONTIERS IN NEUROLOGY
(2022)
Article
Orthopedics
Sarah A. Orban, Jeffery N. Epstein, Devon Carr, Kelsey Logan, Paul J. Gubanich, Craig Sidol, Gregory D. Myer
Summary: Patients with ADHD had higher parent-reported symptoms both before and after mTBI, while females exhibited higher fatigue and emotional symptoms pre-injury and higher symptoms in all domains post-mTBI compared to males. The study highlights the importance of assessing baseline symptoms and considering ADHD status and sex when evaluating mTBI symptom severity in clinical settings.
CLINICAL JOURNAL OF SPORT MEDICINE
(2021)
Article
Clinical Neurology
Johan H. Lee, Katherine G. Holste, Bela J. Selzer, Hugh J. L. Garton, Karin M. Muraszko, Cormac O. Maher
Summary: There is currently no consensus recommendation on the safety of sports participation for pediatric patients with arachnoid cysts (ACs). A prospective survey was conducted to assess the risk of sports-related neurologic injury in both untreated and treated patients. The study found that the rates of sports-related concussion and cyst rupture were low in both patient populations, suggesting that a generally permissive posture toward sports participation can be advocated.
Article
Orthopedics
Stephen C. Bunt, Nyaz Didehbani, Tahnae Tarkenton, Heidi Rossetti, Cason Hicks, Bert Vargas, Cheryl Silver, Paul Nakonezny, Kathleen Bell, Hunt Batjer, C. Munro Cullum
Summary: This study revealed that adolescent female and male athletes may experience different symptoms after a sports-related concussion, with girls showing significantly higher severity of symptoms such as headache, dizziness, sensitivity to light and noise, and pressure in the head.
CLINICAL JOURNAL OF SPORT MEDICINE
(2021)
Article
Clinical Neurology
Masaru Teramoto, Eliza Banchoff Grover, Jordan Cornwell, Rachel Zhang, Marie Boo, Jamshid Ghajar, Angela Lumba-Brown
Summary: A study on sports concussion assessments among college athletes found that there are some differences between females and males in symptom reporting and neurocognitive impairments. Although no sex-based differences were observed in most concussion assessment parameters, females showed significant differences in symptom provocation using the VOMS.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2022)
Article
Neurosciences
Nathan W. Churchill, Michael G. Hutchison, Simon J. Graham, Tom A. Schweizer
Summary: This study found significant sex differences in brain recovery after concussion, with males showing greater reductions in occipital-parietal blood flow and increases in callosal mean diffusivity, while females had greater reductions in corona radiata fractional anisotropy. These findings provide new insights into how the brain recovers after a concussion, showing sex differences in both the acute and chronic phases of injury.
HUMAN BRAIN MAPPING
(2021)
Article
Sport Sciences
Siobhan O'Connor, Deirdre Geaney, Enda F. F. Whyte, Anthony P. P. Kontos, Philip J. J. O'Halloran, Erica Beidler
Summary: Irish collegiate athletes have concerns about concussion, and female athletes and those with a concussion history display more negative perceptions.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2023)
Article
Sport Sciences
Christopher M. Fox, Jonathan G. Wu, Lucia Chen, Dena L. Florczyk
Summary: The study aimed to assess injury patterns in collegiate club quidditch athletes over three seasons. The overall injury incidence rate for quidditch injuries was 4.55 per 1000 athlete exposures. Male athletes had a higher injury rate compared to females, with the most common injuries being lower extremity injuries and sprains. The study identified areas for improvement in education, injury prevention, and athlete care, particularly in relation to concussions in quidditch.
SPORTS MEDICINE-OPEN
(2021)
Article
Clinical Neurology
Clare M. Wieland, Katherine G. Holste, Bela Selzer, Hugh J. L. Garton, Karin M. Muraszko, Cormac O. Maher
Summary: This study aims to investigate the safety of sports participation for pediatric patients with CM-I, and concludes that in most cases, these patients can participate in sports with low risk of concussion and neurological injury.
Review
Rehabilitation
Nicole Pacheco, Shirin Mollayeva, Binu Jacob, Angela Colantonio, Tatyana Mollayeva
Summary: The study found that there is insufficient and inconclusive scientific evidence on the effectiveness of cognitive interventions for adults with traumatic spinal cord injury, requiring more research to determine effective intervention strategies. Current interventions include drug therapy, nerve stimulation, diet modifications, and inpatient rehabilitation, with the latter showing a small but positive effect.
DISABILITY AND REHABILITATION
(2021)
Article
Rehabilitation
Tatyana Mollayeva, Caterina Bordignon, Maryam Ishtiaq, Heather Colquhoun, Andrea D'Souza, Patrick Archambault, John Lewko, Enrico Quilico, Angela Colantonio
Summary: This research aimed to understand the experiences of biological sex and social gender phenomena among patients with traumatic brain injury, as well as their educational needs. The study found that patients faced limitations in seeking information due to the complexity of the subject, dependence on others, and uncertainty about the course of recovery. Overall, variation in patients' knowledge and desire for information should be considered in patient education recommendations to improve injury prognosis.
DISABILITY AND REHABILITATION
(2021)
Article
Rehabilitation
Sara Hanafy, Vanessa Amodio, Halina (Lin) Haag, Heather Colquhoun, John Lewko, Enrico Quilico, Richard Riopelle, Patrick Archambault, Angela Colantonio, Sally Lindsay, Tatyana Mollayeva
Summary: This study aimed to explore rehabilitation clinicians’ understanding of how sex and gender affect care for patients with traumatic brain injury. The results indicated that there is limited attention to the impact of sex and gender on patient recovery, but clinicians are willing to be educated on the topic to enhance rehabilitation care. The study also highlighted the gendered nature of caregiving and its negative impact on caregiver health.
DISABILITY AND REHABILITATION
(2022)
Article
Rehabilitation
Tatyana Mollayeva, Mitchel Sutton, Michael Escobar, Mackenzie Hurst, Angela Colantonio
Summary: Limited evidence exists on the impact of comorbid spinal cord injury (SCI) on cognitive outcomes in individuals undergoing rehabilitation following newly diagnosed traumatic brain injury (TBI). A population-based study in Ontario, Canada found that patients with TBI and comorbid SCI showed lower cognitive gains in inpatient rehabilitation compared to those with TBI alone, particularly in problem solving and comprehension domains. Targeted strategies to improve cognitive outcomes may be beneficial for those at risk for worse cognitive results.
Article
Neurosciences
Andrea D'Souza, Alexis Fabricius, Vanessa Amodio, Heather Colquhoun, John Lewko, Halina (Lin) Haag, Enrico Quilico, Patrick Archambault, Angela Colantonio, Tatyana Mollayeva
Summary: Research suggests that gender plays a role in men's health beliefs and behaviors, including those related to traumatic brain injury (TBI). Therefore, this qualitative study aimed to explore how gender influences men's perceptions and behaviors in TBI rehabilitation and recovery. The study identified three key themes: undermining treatment, facilitating recovery, and perceptions on return to work. These findings can inform the development of gender-informed therapy strategies and materials.
NEUROPSYCHOLOGICAL REHABILITATION
(2022)
Article
Neurosciences
T. Lan Chun Yang, A. Colantonio, Tatyana Mollayeva
Summary: The study found that individuals with mTBI may not accurately assess their sleep duration, highlighting the importance of conducting PSG in clinical settings where sleep duration is a concern.
Review
Rehabilitation
Sara Hanafy, Chen Xiong, Vincy Chan, Mitchell Sutton, Michael Escobar, Angela Colantonio, Tatyana Mollayeva
Summary: A review of 22 studies found that comorbidities have a negative impact on functional outcomes in TBI patients, affecting cognitive and physical functioning. The strength of association varied between studies, with factors such as TBI severity, sex/gender, and age playing important roles in the relationship. Due to methodological heterogeneity, meta-analyses were not conducted.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Review
Clinical Neurology
Tatyana Mollayeva, Shirin Mollayeva, Nicole Pacheco, Angela Colantonio
Summary: Studies on the impact of sex and gender on traumatic brain injury outcomes show inconsistent results, highlighting the need for a comprehensive and consistent methodology incorporating social equity parameters.
FRONTIERS IN NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Tatyana Mollayeva, Andrew Tran, Vincy Chan, Angela Colantonio, Michael D. Escobar
Summary: This study utilized data mining and information visualization methods to analyze complex and multidimensional data related to traumatic brain injury (TBI) events. The results revealed differences in host, agent, and environmental patterns between male and female TBI patients, which is significant for injury prevention and gender-transformative care research.
BMC MEDICAL RESEARCH METHODOLOGY
(2022)
Article
Neurosciences
Mohsen Soltanifar, Michael Escobar, Annie Dupuis, Andre Chevrier, Russell Schachar
Summary: This study aimed to measure the reactive inhibition and proactive inhibition components within the stop-signal paradigm. A method was proposed to precisely estimate the entire distribution of proactive inhibition. The results showed that the proposed model accurately described the distribution and shape features of proactive inhibition.
Article
Medical Informatics
Christopher Meaney, Michael Escobar, Therese A. Stukel, Peter C. Austin, Liisa Jaakkimainen
Summary: This study comparatively evaluates several methods for estimating topic models and finds that temporal topic models can consistently identify latent thematic patterns in clinical text data.
JMIR MEDICAL INFORMATICS
(2022)
Review
Neurosciences
Cori Snow, Bristol Baldwin, Mackenzie Hurst, Angela Colantonio, Tatyana Mollayeva
Summary: This study found that work-related traumatic brain injury (wr-TBI) is increasing, and the pre-injury health status is associated with wr-TBI. There are sex differences in Person-Environment-Occupation (PEO) variables, with males having a lower risk of wr-TBI. In addition, individuals with mood disorders and those in non-labourer occupations are more likely to sustain wr-TBI from falls.
Review
Medicine, General & Internal
Syeda T. Rizvi, Jhankhana S. Shah, Sarah Shaaya, Tatyana Mollayeva
Summary: This research examines the use of pharmacotherapy in reducing cognitive impairments in adult patients with primary CNS infections. The results show inconsistent effects of drug treatment on cognitive domains in patients with LD, HSV-1, and CJD, with low certainty in the evidence.
Review
Medicine, General & Internal
Vincy Chan, Maria Jennifer Estrella, Sara Hanafy, Zoe Colclough, Julie Michele Joyce, Jessica Babineau, Angela Colantonio
Summary: Most clinical practice guidelines prioritize treatment and cost-effectiveness, lacking considerations for equity for disadvantaged groups. Integration of evidence regarding homelessness and traumatic brain injury, as well as engagement of disadvantaged populations, is crucial for improving care quality and equity.
