Article
Cardiac & Cardiovascular Systems
Fozia Z. Ahmed, Carina Blomstrom-Lundqvist, Heather Bloom, Christopher Cooper, Christopher Ellis, Andreas Goette, Arnold J. Greenspon, Charles J. Love, Jens Brock Johansen, Francois Philippon, Khaldoun G. Tarakji, Reece Holbrook, Lou Sherfesee, Ying Xia, Swathi Seshadri, Daniel R. Lexcen, Andrew D. Krahn
Summary: The PADIT infection risk score, developed from a large dataset, identified five independent predictors of CIED infection. A validation study using U.S. healthcare claims data confirmed the predictive value of the risk score, especially when combined with prior CIED infection history, in identifying high-risk patients for targeted interventions to reduce CIED infection risk.
Article
Cardiac & Cardiovascular Systems
Michele Malagu, Francesco Vitali, Alessandro Brieda, Paolo Cimaglia, Martina De Raffele, Enea Tazzari, Cristina Musolino, Cristina Balla, Matteo Serenelli, Rosario Cultrera, Claudio Rapezzi, Matteo Bertini
Summary: In a study involving patients undergoing CIED surgery, stratification of infective risk guided antibiotic prophylaxis with similar infection rates observed between high and low-risk groups after 250 days of follow-up. Active neoplasia, haematoma, and reintervention were identified as independent risk factors for CIED-related infection.
Review
Cardiac & Cardiovascular Systems
Grzegorz Slawinski, Maciej Kempa, Andrzej Przybylski
Summary: The importance of CIEDs in treating cardiac rhythm disturbances, heart failure, and preventing sudden cardiac death is undeniable. However, CIED therapy is associated with complications, particularly infections, which have a significant impact on prognosis. This review summarizes current knowledge on diagnosing and managing CIED infections and also discusses alternative methods like subcutaneous defibrillators, leadless pacemakers, and wearable cardioverter defibrillators.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Raul Weiss, George E. Mark, Mikhael F. El-Chami, Mauro Biffi, Vincent Probst, Pier D. Lambiase, Marc A. Miller, Timothy McClernon, Linda K. Hansen, Bradley P. Knight, Larry M. Baddour
Summary: An expert panel consensus was developed using a process mapping methodology to provide guidance on minimizing the risk of infection in patients with subcutaneous implantable cardioverter-defibrillators (S-ICDs). The consensus offers recommended steps for patient preparation, S-ICD implantation, and postoperative management, which can help clinicians adopt interventions to reduce the risk of S-ICD infection.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Thomas F. Deering, John N. Catanzaro, David A. Woodard
Summary: This study found that the use of antibiotics, especially gentamicin, in biologic envelope hydration solution may reduce infection risk in CIED procedures. Additionally, utilizing antibacterial envelopes without adjunct IV ABX may not be sufficient to reduce infection rates.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Jacopo Francesco Imberti, Davide Antonio Mei, Riccardo Fontanesi, Luigi Gerra, Niccolo Bonini, Marco Vitolo, Vincenzo Turco, Edoardo Casali, Giuseppe Boriani
Summary: This study describes the incidence of CIED-related infection and death in a contemporary cohort of CIED patients and identifies potential predictors. The results show a low incidence of CIED-related infections and a high mortality rate, which are associated with clinical factors.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Carina Blomstrom-Lundqvist, Bozena Ostrowska
Summary: CIED infections are a significant concern despite recommended prevention strategies, with infection rates continuing to rise and leading to increased healthcare costs. Recent trials aim to provide important steps for better prevention of device infections, emphasizing the importance of adherence to recommendations.
Article
Cardiac & Cardiovascular Systems
Khaldoun G. Tarakji, Panagiotis Korantzopoulos, Francois Philippon, Mauro Biffi, Suneet Mittal, Jeanne E. Poole, Charles Kennergren, Daniel R. Lexcen, Jeff D. Lande, Swathi Seshadri, Bruce L. Wilkoff
Summary: Among WRAP-IT patients, the risk of hematoma was 2.2%. Control patients with hematoma had a significantly higher risk of developing major CIED infection, which was effectively reduced by 82% with antibacterial envelope use compared to control patients.
Review
Cardiac & Cardiovascular Systems
Giuseppe Boriani, Haran Burri, Emma Svennberg, Jacopo Francesco Imberti, Jose Luis Merino, Christophe Leclercq
Summary: Remote monitoring is recommended as a standard care for the follow-up of CIEDs, as it can detect issues and changes in cardio-respiratory functions. However, the heterogeneity in reimbursement policies across Europe is a significant barrier to widespread implementation.
Article
Oncology
Mario Levis, Alessandro Andreis, Serena Badellino, Carlo Budano, Donatella Caivano, Marzia Cerrato, Erika Orlandi, Arianna Bissolino, Gloria Angelico, Chiara Cavallin, Francesca R. Giglioli, Gaetano M. De Ferrari, Umberto Ricardi
Summary: The study evaluated the effects of thoracic SABR on CIEDs in 34 patients, demonstrating that SABR is safe for CIEDs when the dose is kept under 2 Gy and the beam energy is equal to or less than 10 MV.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Medicine, General & Internal
Simone Gulletta, Giulio Falasconi, Lorenzo Cianfanelli, Alice Centola, Gabriele Paglino, Manuela Cireddu, Andrea Radinovic, Giuseppe D'Angelo, Alessandra Marzi, Simone Sala, Nicolai Fierro, Caterina Bisceglia, Giovanni Peretto, Nadia Di Muzio, Paolo Della Bella, Pasquale Vergara, Italo Dell'Oca
Summary: This study reports the ten-year real-world experience of a tertiary multidisciplinary teaching hospital in managing patients with cardiac implantable electronic devices (CIEDs) undergoing radiotherapy (RT). The results show infrequent changes in device parameters and occurrence of arrhythmias, with no clinically significant adverse events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hui-Chen Han, Nathaniel M. Hawkins, Charles M. Pearman, David H. Birnie, Andrew D. Krahn
Summary: CIED infection is a serious complication with a 1% infection rate, influenced by technical, patient, and procedural factors. Considering these factors is essential for minimizing infection risk.
Article
Cardiac & Cardiovascular Systems
Andrew Y. Lin, Tatiana Saul, Omar M. Aldaas, Florentino Lupercio, Gordon Ho, Travis Pollema, Victor Pretorius, Ulrika Birgersdotter-Green
Summary: This study compared the impact of early versus delayed infected CIED extraction on patient outcomes. The results showed that delayed extraction was associated with worse outcomes. This underscores the importance of early detection and prompt management strategies.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Fahd Nadeem, Arismendy Nunez Garcia, Cao Thach Tran, Michael Wu
Summary: The study found that Apple's iPhone 12 Pro Max MagSafe technology can cause clinically significant magnet interference on cardiac implantable electronic devices (CIED), potentially inhibiting lifesaving therapy.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Anesthesiology
H. Thomas, C. Plummer, I. J. Wright, P. Foley, A. J. Turley
Summary: This document provides practical guidance for the management of patients with cardiac implantable electronic devices during surgical intervention, aiming to minimize the risk of electromagnetic interference. It includes detailed instructions for pre-operative assessment and measures to ensure safe care for these patients.
Letter
Cardiac & Cardiovascular Systems
Atul Verma, George Wells, Andrew C. T. Ha, Paulus Kirchhof, Gerhard Hindricks, Jeff S. Healey, Michael D. Hill, Mukul Sharma, Jean Champagne, Vidal Essebag, Hein Heidbuchel, Prashanthan Sanders, David H. Birnie
AMERICAN HEART JOURNAL
(2022)
Letter
Cardiac & Cardiovascular Systems
Amanda K. Morrow, T. Andrew Zabel, Jennifer Dodson, Sarah A. Korth
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Yves Longtin, Leighanne O. Parkes, Hugues Charest, Stacy Rajarison, Gerasimos J. Zaharatos, Judith Fafard, Michel Roger, Gaston De Serres
Summary: The results of this small study suggest that infectivity may be prolonged among older individuals.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Maxime-Antoine Tremblay, Hui Yin, Fares Ould-Brahim, Mona Abou Sader, Yves Longtin
Summary: This study investigated whether an anonymous automated electronic monitoring system (EMS) could be used to compare hand hygiene (HH) performance of individual nurses. The results showed an association between a room's HH rate and its assigned nurse, indicating potential value for an individualized feedback strategy.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Article
Public, Environmental & Occupational Health
Sara Carazo, Jasmin Villeneuve, Denis Laliberte, Yves Longtin, Denis Talbot, Richard Martin, Geoffroy Denis, Francine Ducharme, Bianka Paquet-Bolduc, Genevieve Anctil, Sandrine Hegg-Deloye, Gaston De Serres
Summary: This study evaluated the risk factors associated with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare workers (HCWs) in Quebec, Canada. The study found that the nature of work, workplace and household exposures, and infection prevention and control measures were all associated with the risk of infection. Among patient-facing HCWs, household contact and frequent exposure to infected patients and coworkers were the major risk factors.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
J. G. Andrade, M. W. Deyell, L. Macle, G. A. Wells, M. Bennett, V Essebag, J-F Roux, D. Yung, A. Skanes, Y. Khaykin, C. Morillo, U. Jolly, P. Novak, E. Lockwood, G. Amit, P. Angaran, J. Sapp, S. Wardell, S. Lauck, J. Cadrin-Tourigny, S. Kochhaeuser, A. Verma
Summary: This study evaluated the treatment effect of catheter cryoballoon ablation versus antiarrhythmic drug therapy for initial paroxysmal atrial fibrillation. The results showed that in the 3-year follow-up period, the catheter ablation group had a lower incidence of persistent atrial fibrillation and recurrent atrial tachyarrhythmia compared to the drug therapy group. Additionally, the proportion of time in atrial fibrillation was also lower in the ablation group. Therefore, catheter ablation is recommended as the initial treatment for initial paroxysmal atrial fibrillation.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Girish M. Nair, David H. Birnie, Pablo B. Nery, Calum J. Redpath, Jean-Francois Sarrazin, Jean-Francois Roux, Ratika Parkash, Martin Bernier, Laurence D. Sterns, John Sapp, Paul Novak, George Veenhuyzen, Carlos A. Morillo, Sheldon M. Singh, Mouhannad M. Sadek, Mehrdad Golian, Andres Klein, Marcio Sturmer, Vijay S. Chauhan, Paul Angaran, Martin S. Green, Jordan Bernick, George A. Wells, Vidal Essebag
Summary: In this study, an augmented double wide-area circumferential ablation (WACA) did not show superiority in preventing recurrent atrial arrhythmias compared to a standard single WACA in patients with paroxysmal AF. The additional ablation did not improve freedom from atrial arrhythmias or safety.
Article
Cardiac & Cardiovascular Systems
Hui-Chen Han, Jia Wang, David H. Birnie, Marco Alings, Francois Philippon, Ratika Parkash, Jaimie Manlucu, Paul Angaran, Claus Rinne, Benoit Coutu, R. Aaron Low, Vidal Essebag, Carlos Morillo, Jeffrey S. Healey, Damian Redfearn, Satish Toal, Giuliano Becker, Michel DeGrace, Bernard Thibault, Eugene Crystal, Stanley Tung, John LeMaitre, Omar Sultan, Matthew Bennett, Jamil Bashir, Felix Ayala-Paredes, Philippe Gervais, Leon Rioux, Martin E. W. Hemels, Leon H. R. Bouwels, Derek V. Exner, Paul Dorian, Stuart J. Connolly, Yves Longtin, Andrew D. Krahn
Summary: Cardiac implantable electronic device (CIED) infection is a potentially devastating complication with a high mortality rate. This study analyzed data from 19,559 patients and found that CIED infections were most common within the first 3 months after the procedure. Early systemic infections and delayed localized infections were associated with increased mortality, highlighting the importance of early detection and treatment.
Article
Medicine, General & Internal
Bruce L. Wilkoff, Gerasimos Filippatos, Christophe Leclercq, Michael R. Gold, Ahmad S. Hersi, Kengo Kusano, Wilfried Mullens, Michael Felker, Charan Kantipudi, Mikhael F. El-Chami, Vidal Essebag, Bertrand Pierre, Francois Philippon, Francisco Perez-Gil, Eugene S. Chung, Juan Sotomonte, Stanley Tung, Balbir Singh, Babak Bozorgnia, Satish Goel, Hans Holger Ebert, Niraj Varma, Kara J. Quan, Fiorella Salerno, Bart Gerritse, Janelle van Wel, Daniel E. Schaber, Dedra H. Fagan
Summary: Compared with conventional CRT, adaptive CRT did not significantly reduce the incidence of all-cause death or intervention for heart failure decompensation in the included population of patients with heart failure, left bundle branch block, and intact AV conduction. Death and heart failure decompensation rates were low with both CRT therapies, suggesting a greater response to CRT occurred in this population than in patients in previous trials.
Article
Health Care Sciences & Services
Simon Berthelot, Yves Longtin, Manuele Margni, Jason Robert Guertin, Annie Leblanc, Tania Marx, Khadidiatou Mangou, Ariane Bluteau, Diego Mantovani, Sergey Mikhaylin, Frederic Bergeron, Valerie Dancause, Anne Desjardins, Nadia Lahrichi, Danielle Martin, Charles Jerome Sossa, Philippe Lachapelle, Stephane Schaal, Isabelle Genest, Anne Gignac, Stephane Tremblay, Eric Hufty, Lynda Belanger, Erica Beatty
Summary: This study aims to evaluate the eco-efficient use of personal protective equipment (PPE) in emergency departments (EDs). It will assess the clinical effectiveness, financial cost, and ecological footprint of PPE use. The first three phases have started, with results expected in 2024.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Cardiac & Cardiovascular Systems
Michelle Samuel, Jeff S. Healey, Isabelle Nault, Laurence D. Sterns, Vidal Essebag, Christopher Gray, Tomasz Hruczkowski, Martin Gardner, Ratika Parkash, John L. Sapp
Summary: This study compared the effects of catheter ablation and escalated antiarrhythmic drug (AAD) therapy on ventricular tachycardia (VT) events and implantable cardioverter-defibrillator (ICD) therapy burden in patients with previous myocardial infarction (MI) and drug-refractory VT. The results showed that patients in the ablation group had significantly lower burden of shock-treated VT events and appropriate ICD therapy compared to those in the escalated AAD therapy group.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Review
Medicine, General & Internal
Mohamed N. Al Rawahi, Juhaina S. Al-Maqbali, Jawahar Al Noumani, Abdullah M. Al Alawi, Vidal Essebag
Summary: The use of novel oral anticoagulants (NOAC) in patients with moderate to severe mitral stenosis (MS) and atrial fibrillation (AF) is not recommended. However, our systematic review suggests potential efficacy and safety of NOAC compared to vitamin K antagonist (VKA) in this population. Further clinical trials are needed to establish the safety profile and clinical effectiveness of NOAC in this high-risk population.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Jacqueline Joza, Girish M. Nair, David H. Birnie, Pablo B. Nery, Calum J. Redpath, Jean-Francois Sarrazin, Jean Champagne, Jordan Bernick, George A. Wells, Vidal Essebag
Summary: This study compares the clinical efficacy and safety outcomes of a high-power, short-duration (HPSD) strategy versus a low-power, long-duration (LPLD) strategy in patients with paroxysmal atrial fibrillation (AF) undergoing pulmonary vein isolation (PVI). The results show that the HPSD strategy has a significantly shorter procedural time and similar efficacy in terms of clinical arrhythmia recurrence compared to the LPLD strategy, without an increased risk of harm.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Mark Hofmeister, Robert S. Sheldon, Eldon Spackman, Satish R. Raj, Mario Talajic, Giuliano Becker, Vidal Essebag, Deborah Ritchie, Carlos A. Morillo, Andrew Krahn, Shahana Safdar, Connor Maxey, Fiona Clement
Summary: The SPRITELY trial showed that in older adults with bifascicular block and syncope, using a pacemaker strategy is more cost-effective than an implantable cardiac monitor strategy.
Article
Cardiac & Cardiovascular Systems
Robert Sheldon, Mario Talajic, Anthony Tang, Giuliano Becker, Vidal Essebag, Omar Sultan, Adrian Baranchuk, Debbie Ritchie, Carlos Morillo, Andrew Krahn, Michele Brignole, Braden Manns, Connor Maxey, Satish R. Raj
Summary: This study aimed to compare the effectiveness of empiric permanent pacing with acting on the results of an implantable cardiac monitor (ICM) for the care of patients with bifascicular block. The results showed that empiric permanent pacing reduced major adverse events but did not reduce syncope episodes.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2022)