Tumor mutational burden and response to programmed cell death protein 1 inhibitors in a case series of patients with metastatic desmoplastic melanoma
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2019)
Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 80, Issue 6, Pages 1780-1782Publisher
MOSBY-ELSEVIER
Keywords
Categories
Ask authors/readers for more resources
Authors
I am an author on this paper
Reviews
Recommended
Tumor mutational burden predicts the efficacy of pembrolizumab monotherapy: a pan-tumor retrospective analysis of participants with advanced solid tumors
Razvan Cristescu, Deepti Aurora-Garg, Andrew Albright, Lei Xu, Xiao Qiao Liu, Andrey Loboda, Lixin Lang, Fan Jin, Eric H. Rubin, Alexandra Snyder, Jared Lunceford
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2022)
Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy by Tumor Mutational Burden in Metastatic Castration-Resistant Prostate Cancer
Ryon P. Graf, Virginia Fisher, Janick Weberpals, Ole Gjoerup, Marni B. Tierno, Richard S. P. Huang, Nicolas Sayegh, Douglas Lin, Kira Raskina, Alexa B. Schrock, Eric Severson, James F. Haberberger, Jeffrey S. Ross, James Creeden, Mia A. Levy, Brian M. Alexander, Geoffrey R. Oxnard, Neeraj Agarwal
JAMA NETWORK OPEN (2022)
Normalization of electroretinogram and symptom resolution of melanoma-associated retinopathy with negative autoantibodies after treatment with programmed death-1 (PD-1) inhibitors for metastatic melanoma
Karam Khaddour, Sangeeta Khanna, Michael Ansstas, Ishaan Jakhar, Sonika Dahiya, Laurin Council, George Ansstas
CANCER IMMUNOLOGY IMMUNOTHERAPY (2021)
Dermatological adverse events under programmed cell death-1 inhibitors as a prognostic marker in metastatic melanoma
Rony Shreberk-Hassidim, Lilach Aizenbud, Shalev Lussheimer, Elena Thomaidou, Tali Bdolah-Abram, Sharon Merims, Aron Popovtzer, Alex Maly, Michal Lotem, Abraham Zlotogorski
DERMATOLOGIC THERAPY (2022)
Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors
Camila B. Xavier, Carlos Diego H. Lopes, Beatriz M. Awni, Eduardo F. Campos, Joao Pedro B. Alves, Anamaria A. Camargo, Gabriela D. A. Guardia, Pedro A. F. Galante, Denis L. Jardim
CANCERS (2022)
Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma
Robert Haddad, Tanguy Y. Seiwert, Laura Q. M. Chow, Shilpa Gupta, Jared Weiss, Iris Gluck, Joseph P. Eder, Barbara Burtness, Makoto Tahara, Bhumsuk Keam, Hyunseok Kang, Kei Muro, Andrew Albright, Robin Mogg, Mark Ayers, Lingkang Huang, Jared Lunceford, Razvan Cristescu, Jonathan Cheng, Ranee Mehra
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2022)
Tumor Mutational Burden in Breast Cancer: Current Evidence, Challenges, and Opportunities
Romualdo Barroso-Sousa, Jana Priscila Pacifico, Sarah Sammons, Sara M. Tolaney
CANCERS (2023)
PD-L1 expression, tumor mutational burden, and immune cell infiltration in non-small cell lung cancer patients with epithelial growth factor receptor mutations
Tiantian Ma, Jin Jiao, Ran Huo, Xiaofang Li, Guotao Fang, Qi Zhao, Weiwei Liu, Xiao Han, Chenglin Xi, Yanan Wang, Yanhong Shang
FRONTIERS IN ONCOLOGY (2022)
Tumor Mutational Burden for Predicting Prognosis and Therapy Outcome of Hepatocellular Carcinoma
Daniela Gabbia, Sara De Martin
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Baseline and post-treatment biomarkers of resistance to anti-PD-1 therapy in acral and mucosal melanoma: an observational study
Irene M. Shui, Xiao Qiao Liu, Qing Zhao, Seung Tae Kim, Yuan Sun, Jennifer H. Yearley, Tasmiah Choudhury, Andrea L. Webber, Clemens Krepler, Razvan Cristescu, Jeeyun Lee
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2022)
Outcomes and a prognostic classifier in patients with microsatellite instability-high metastatic gastric cancer receiving PD-1 blockade
Giovanni Randon, Yu Aoki, Romain Cohen, Leonardo Provenzano, Vincenzo Nasca, Samuel J. Klempner, Steven B. Maron, Riccardo Cerantola, Joseph Chao, Lorenzo Fornaro, Walter Ferrari Bravo, Filippo Ghelardi, Margherita Ambrosini, Paolo Manca, Massimiliano Salati, Akihito Kawazoe, Valerie Zhu, Darren Cowzer, Virginia Genovesi, Sara Lonardi, Kohei Shitara, Thierry Andre, Filippo Pietrantonio
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2023)
PET/CT scan and biopsy-driven approach for safe anti-PD-1 therapy discontinuation in patients with advanced melanoma
Geoffrey T. Gibney, Jacob Zaemes, Shelly Shand, Neil J. Shah, David Swoboda, Kellie Gardner, Arash Radfar, Vesna Petronic-Rosic, Michael J. Reilly, Waddah B. Al-Refaie, Suthee Rapisuwon, Michael B. Atkins
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)
SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy
Xiaobin Zheng, Jing Lin, Jiani Xiong, Yanfang Guan, Bin Lan, Yi Li, Xuan Gao, Zhaodong Fei, Lisha Chen, Lizhu Chen, Ling Chen, Gang Chen, Zengqing Guo, Xin Yi, Weiguo Cao, Xinghao Ai, Chengzhi Zhou, Xiaofeng Li, Jun Zhao, Xiangtao Yan, Qitao Yu, Lu Si, Yu Chen, Chuanben Chen
BMC CANCER (2023)
Integration of comprehensive genomic profiling, tumor mutational burden, and PD-L1 expression to identify novel biomarkers of immunotherapy in non-small cell lung cancer
Yunfei Shi, Youming Lei, Li Liu, Shiyue Zhang, Wenjing Wang, Juan Zhao, Songhui Zhao, Xiaowei Dong, Ming Yao, Kai Wang, Qing Zhou
CANCER MEDICINE (2021)
Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burden
Vaia Florou, Charalampos S. Floudas, Asaf Maoz, Abdul Rafeh Naqash, Carter Norton, Aik Choon Tan, Ethan S. Sokol, Garrett Frampton, Heloisa P. Soares, Sonam Puri, Umang Swami, Breelyn Wilky, Peter Hosein, Jonathan Trent, Gilberto de Lima Lopes, Wungki Park, Ignacio Garrido-Laguna
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2023)
Early-onset metastatic and clinically advanced prostate cancer is a distinct clinical and molecular entity characterized by increased TMPRSS2-ERG fusions
Zachary R. Chalmers, Michael C. Burns, Ericka M. Ebot, Garrett M. Frampton, Jeffrey S. Ross, Maha H. A. Hussain, Sarki A. Abdulkadir
PROSTATE CANCER AND PROSTATIC DISEASES (2021)
Pan-cancer landscape of CD274 (PD-L1) copy number changes in 244 584 patient samples and the correlation with PD-L1 protein expression
Richard S. P. Huang, Karthikeyan Murugesan, Meagan Montesion, Dean C. Pavlick, Douglas A. Mata, Matthew C. Hiemenz, Brennan Decker, Garrett Frampton, Lee A. Albacker, Jeffrey S. Ross
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)
Prediction and characterization of diffuse large B-cell lymphoma cell-of-origin subtypes using targeted sequencing
Sally E. Trabucco, Ethan S. Sokol, Sophia L. Maund, Jay A. Moore, Garrett M. Frampton, Lee A. Albacker, Mikkel Z. Oestergaard, Jeffrey Venstrom, Laurie H. Sehn, Christopher R. Bolen
FUTURE ONCOLOGY (2021)
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
Marcelo Negrao, Ferdinandos Skoulidis, Meagan Montesion, Katja Schulze, Ilze Bara, Vincent Shen, Hao Xu, Sylvia Hu, Dawen Sui, Yasir Y. Elamin, Xiuning Le, Michael E. Goldberg, Karthikeyan Murugesan, Chang-Jiun Wu, Jianhua Zhang, David S. Barreto, Jacqulyne P. Robichaux, Alexandre Reuben, Tina Cascone, Carl M. Gay, Kyle G. Mitchell, Lingzhi Hong, Waree Rinsurongkawong, Jack A. Roth, Stephen G. Swisher, Jack Lee, Anne Tsao, Vassiliki Papadimitrakopoulou, Don L. Gibbons, Bonnie S. Glisson, Gaurav Singal, Vincent A. Miller, Brian Alexander, Garrett Frampton, Lee A. Albacker, David Shames, Jianjun Zhang, John Heymach
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)
Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors
Jonathan W. Riess, Shaila Rahman, Waleed Kian, Claire Edgerly, Andreas M. Heilmann, Russell Madison, Shakti H. Ramkissoon, Shai Shlomi Klaitman, Jon H. Chung, Sally E. Trabucco, Dexter X. Jin, Brian M. Alexander, Samuel J. Klempner, Lee A. Albacker, Garrett M. Frampton, Laila C. Roisman, Vincent A. Miller, Jeffrey S. Ross, Alexa B. Schrock, Jeffrey P. Gregg, Nir Peled, Ethan S. Sokol, Siraj M. Ali
TRANSLATIONAL ONCOLOGY (2021)
Intra-patient stability of tumor mutational burden from tissue biopsies at different time points in advanced cancers
Timothy V. Pham, Aaron M. Goodman, Smruthy Sivakumar, Garrett Frampton, Razelle Kurzrock
GENOME MEDICINE (2021)
Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors
Coren A. Milbury, James Creeden, Wai-Ki Yip, David L. Smith, Varun Pattani, Kristi Maxwell, Bethany Sawchyn, Ole Gjoerup, Wei Meng, Joel Skoletsky, Alvin D. Concepcion, Yanhua Tang, Xiaobo Bai, Ninad Dewal, Pei Ma, Shannon T. Bailey, James Thornton, Dean C. Pavlick, Garrett M. Frampton, Daniel Lieber, Jared White, Christine Burns, Christine Vietz
PLOS ONE (2022)
Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers
Ilya G. Serebriiskii, Valery Pavlov, Rossella Tricarico, Grigorii Andrianov, Emmanuelle Nicolas, Mitchell Parker, Justin Newberg, Garrett Frampton, Joshua E. Meyer, Erica A. Golemis
NATURE COMMUNICATIONS (2022)
A pan-cancer landscape of telomeric content shows that RAD21 and HGF alterations are associated with longer telomeres
Radwa Sharaf, Meagan Montesion, Julia F. Hopkins, Jiarong Song, Garrett M. Frampton, Lee A. Albacker
GENOME MEDICINE (2022)
ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to Anti-Human Epidermal Growth Factor Receptor 2 Therapy in Advanced Gastroesophageal Adenocarcinoma
Liangliang Zhang, Omar Hamdani, Ole Gjoerup, Cheryl Cho-Phan, Jeremy Snider, Emily Castellanos, Halla Nimeiri, Garrett Frampton, Jeffrey M. Venstrom, Geoffrey Oxnard, Samuel J. Klempner, Alexa B. Schrock
JCO PRECISION ONCOLOGY (2022)
Analytical protocol to identify local ancestry-associated molecular features in cancer
Jian Carrot-Zhang, Seunghun Han, Wanding Zhou, Jeffrey S. Damrauer, Anab Kemal, Rameen Canc Genome Atlas Anal Network, Andrew D. Cherniack, Rameen Beroukhim
STAR PROTOCOLS (2021)
Characterization of Non-Small-Cell Lung Cancers With MET Exon 14 Skipping Alterations Detected in Tissue or Liquid: Clinicogenomics and Real-World Treatment Patterns
Jessica K. Lee, Russell Madison, Anthony Classon, Ole Gjoerup, Mark Rosenzweig, Garrett M. Frampton, Brian M. Alexander, Geoffrey R. Oxnard, Jeffrey M. Venstrom, Mark M. Awad, Alexa B. Schrock
JCO PRECISION ONCOLOGY (2021)
Landscape of Biomarkers in Non-small Cell Lung Cancer Using Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry
Richard S. P. Huang, Eric Severson, James Haberberger, Daniel L. Duncan, Amanda Hemmerich, Claire Edgerly, N. Lynn Ferguson, Garrett Frampton, Clarence Owens, Erik Williams, Julia Elvin, Jo-Anne Vergilio, Jonathan Keith Killian, Douglas Lin, Samantha Morley, Deborah McEwan, Oliver Holmes, Natalie Danziger, Michael B. Cohen, Pratheesh Sathyan, Kimberly McGregor, Prasanth Reddy, Jeffrey Venstrom, Rachel Anhorn, Brian Alexander, Charlotte Brown, Jeffrey S. Ross, Shakti H. Ramkissoon
PATHOLOGY & ONCOLOGY RESEARCH (2021)
Prevalence of High Tumor Mutational Burden and Association With Survival in Patients With Less Common Solid Tumors
Changxia Shao, Gerald Li, Lingkang Huang, Scott Pruitt, Emily Castellanos, Garrett Frampton, Kenneth R. Carson, Tamara Snow, Gaurav Singal, David Fabrizio, Brian M. Alexander, Fan Jin, Wei Zhou
JAMA NETWORK OPEN (2020)
Tumor mutational burden is not predictive of cytotoxic chemotherapy response
Mina Nikanjam, Paul Riviere, Aaron Goodman, Donald A. Barkauskas, Garrett Frampton, Razelle Kurzrock
ONCOIMMUNOLOGY (2020)