Article
Dermatology
S. Atilla, O. Gokoz, S. Ozer, G. Elcin
Summary: The study aimed to assess the concordance between Mohs surgeon and pathologist in evaluating Mohs slides, showing a high concordance rate and good inter-rater agreement.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Review
Dermatology
Vincent M. Desiato, Young Jae Byun, Shaun A. Nguyen, Bruce H. Thiers, Terry A. Day
Summary: Sebaceous carcinoma of the eyelid is more common in women, often located on the upper eyelid, and is frequently misdiagnosed initially. There were no statistically significant differences in rates of recurrence, metastasis, and tumor-related mortality between subjects managed with wide local excision and Mohs micrographic surgery.
DERMATOLOGIC SURGERY
(2021)
Article
Dermatology
Andrew Matsumoto, Jeffery N. Li, Martha Matsumoto, Juliana Pineider, Rajiv I. Nijhawan, Divya Srivastava
Summary: Research on the long-term outcomes of high-risk cutaneous squamous cell carcinomas (hrSCC) treated with Mohs micrographic surgery (MMS) is limited. MMS remains an effective treatment for hrSCC, with factors like perineural invasion, poor differentiation, and immunosuppression associated with poor outcomes. Further study is needed on the effect of adjuvant treatment.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Oncology
Jiachen Sun, Lihua Zhang, Minglu Xiao, Shiyi Li, Runkai Chen, Ying Li, Yuguang Yang
Summary: This study provides an updated statistical analysis of Trichilemmal carcinoma (TLC), including its epidemiology, clinical features, diagnosis, and treatment. The incidence of TLC has been increasing in recent years, especially in China. Men aged 60-80 and women over 80 are the most susceptible population, with head and neck being the most common location. TLC's phenotype is not always typical and may be misdiagnosed. Periodic acid-Schiff staining and CD34 can aid in its diagnosis, while surgical excision and Mohs micrographic surgery are effective treatment options that need further improvement to reduce recurrence.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Zihan Nie, Jialu Geng, Xiaolin Xu, Ruiheng Zhang, Dongmei Li
Summary: A nomogram was developed based on potential risk factors to predict eyelid SGC recurrence. Five risk factors were identified, and a predictive model was constructed. The model demonstrated good discrimination ability and has the potential to assist healthcare practitioners in early detection of high-risk patients and tailoring clinical interventions.
Article
Dermatology
C. Natterdahl, J. Kappelin, B. Persson, K. Lundqvist, I Ahnlide, K. Saleh, A. Ingvar
Summary: Older age, previous cryotherapy, and multiple prior surgeries were significantly associated with an increased risk of MMS requiring >= 3 stages. Recurrent BCC was associated with the risk of complicated MMS in partially adjusted multivariate analyses, but not in the fully adjusted analyses. Knowledge of these risk factors may help improve the planning of Mohs surgeries.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Dermatology
Hannah Ceder, Malin Gronberg, John Paoli
Summary: This retrospective study compared primary and recurrent facial high-risk basal cell carcinomas treated with Mohs micrographic surgery. Primary tumors required fewer surgery stages, had smaller final defect sizes, and were more often reconstructed by primary closure compared to recurrent or incompletely excised tumors. Improved adherence to Mohs micrographic surgery indications for primary tumors could lead to better resource utilization and patient outcomes.
ACTA DERMATO-VENEREOLOGICA
(2021)
Article
Dermatology
William T. N. Hunt, Toby G. Nelson
Summary: By surveying international Mohs surgeons, this study aims to characterize variation in margin threshold assessment, surgeon background characteristics, and tissue processing and intraoperative approaches.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Dermatology
Ryan B. Thorpe, Kyle R. Covington, Hillary G. Caruso, Ann P. Quick, Olga Zolochevska, Gregory M. Bricca, Michael Campoli, James R. DeBloom, Michael J. Fazio, Bradley N. Greenhaw, E. Brent Kirkland, Mac L. Machan, David G. Brodland, John A. Zitelli
Summary: This study aimed to develop a nomogram integrating 31-GEP with relevant clinical factors to improve prognostic accuracy for patients with cutaneous melanoma. The nomogram, which combines 31-GEP results and T stage, accurately predicts the risk of metastasis and shows a significant linear correlation in validation. It provides clinically useful prognostic information noninvasively and outperforms T stage or 31-GEP alone.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Review
Dermatology
Michelle A. Boettler, Ashley N. Gray, Merrick A. Brodsky, Kathryn T. Shahwan, David R. Carr
Summary: Verrucous carcinoma is a rare and locally aggressive variant of squamous cell carcinoma. Wide local excision is the most common treatment, but has high rates of recurrence. This study summarized the cases of verrucous carcinoma treated with Mohs micrographic surgery and found that Mohs surgery has lower recurrence and metastasis rates, suggesting it as a first-line treatment option.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Review
Medicine, General & Internal
Shiwei Huang, Yang Xia, Yueyang Zhu, Zhiyuan Ren, Yaru Dong
Summary: Microcystic adnexal carcinoma (MAC) is a rare and low-grade malignant skin tumor that often occurs in the head and neck region. However, primary eyelid or orbital MAC is very rare. It is characterized by a high rate of misdiagnosis, local recurrence, and serious complications. Early and accurate diagnosis, complete excision, long-term follow-up, and a multidisciplinary team are crucial for the management of eyelid and orbital MAC.
Article
Dermatology
Amanda Maisel-Campbell, Katherine A. Lin, Sarah A. Ibrahim, Bianca Y. Kang, Noor Anvery, McKenzie A. Dirr, Rachel E. Christensen, Juliet L. Aylward, Omar Bari, Hamza Bhatti, Diana Bolotin, Basil S. Cherpelis, Joel L. Cohen, Sean Condon, Sheila Farhang, Bahar Firoz, Algin B. Garrett, Roy G. Geronemus, Nicholas J. Golda, Tatyana R. Humphreys, Eva A. Hurst, Oren H. Jacobson, S. Brian Jiang, Pritesh S. Karia, Arash Kimyai-Asadi, David J. Kouba, James G. Lahti, Martha Laurin Council, Marilyn Le, Deborah F. MacFarlane, Ian A. Maher, Stanley J. Miller, Eduardo K. Moioli, Meghan Morrow, Julia Neckman, Timothy Pearson, Samuel R. Peterson, Christine Poblete-Lopez, Chad L. Prather, Jennifer S. Ranario, Ashley G. Rubin, Chrysalyne D. Schmults, Andrew M. Swanson, Christopher Urban, Y. Gloria Xu, Murad Alam
Summary: This study found that older patients who received Mohs surgery often had high functional status, high-risk tumors, and tumors located on the face. These findings suggest that timely surgical treatment may be appropriate in older patients given that their tumors may be aggressive, painful, disfiguring, and anxiety provoking.
Article
Dermatology
Mike C. M. van Zon, Jose D. van der Waa, Mitko Veta, Gertruud A. M. Krekels
Summary: The study showed that deep learning models based on whole-slide images can be a feasible option to improve the clinical workflow and reduce costs in histological analysis of BCC in MMS.
EXPERIMENTAL DERMATOLOGY
(2021)
Article
Dermatology
Kevin Shi, Laura Wang, Divya Srivastava, Rajiv I. Nijhawan
Summary: This study evaluated the outcomes and factors associated with poor outcomes of periocular tumors treated with Mohs micrographic surgery (MMS). The results showed that MMS offers excellent cure rates for periocular cutaneous tumors, with no recurrences observed for squamous cell carcinoma, adnexal carcinoma, or melanoma. However, previously treated basal cell carcinomas were found to have a higher risk for recurrence after MMS.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Dermatology
Rumsha Salman, Caroline Daly, Advika Dani, Amarachi Eseonu, Kristin Bibee, Jeffrey F. Scott
Summary: This study retrospectively analyzed the medical records of patients undergoing Mohs micrographic surgery for keratinocyte carcinoma between July 1, 2019 and February 28, 2021 to investigate the impact of time to treatment (TTT) on surgical characteristics. The study found that increasing TTT was not associated with an increased utilization of flap or graft repairs. Although a 42-day increase in TTT was linked to an increase in the post-operative surgical defect size, TTT was not associated with repair length or flap/graft repair area. In conclusion, TTT did not independently influence the complexity of Mohs reconstruction within the studied time range.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Yafen Wang, Zonggui Chen, Xiong Zhang, Xiaocheng Weng, Jikai Deng, Wei Yang, Fan Wu, Shaoqing Han, Chao Xia, Yu Zhou, Yu Chen, Xiang Zhou
Summary: This study presents a method for detecting f(5)C modifications in RNA and a transcriptome-wide f(5)C mapping technique called f(5)C-seq. Over 1000 f(5)C sites were identified in Saccharomyces cerevisiae using f(5)C-seq, and it was found that f(5)C has a preference for wobble sites in mRNA, suggesting its potential role in translation regulation.
ACS CHEMICAL BIOLOGY
(2022)
Article
Chemistry, Physical
Zhiqian Yang, Liqun Duan, Gang Chang, Wenke Zhou, Zhi Zhang, Fan Wu, Aming Xie, Ziming Xiong
Summary: In this study, a series of carbon microfiber/FeS composites were synthesized using a molten-salt-guided synthetic strategy. The microstructures, electromagnetic response behaviors, and microwave absorption properties of these composites were systematically investigated. The results showed that the prepared composites exhibited effective microwave absorption performance, and the choice of molten salt system had an influence on the properties of the composites.
Article
Thermodynamics
Fan Wu, An Han, Wei Jiang, Yanan Yue, Danmei Xie
Summary: The complex flow field at low load has a significant impact on the aerodynamic performance of steam turbines. To improve performance under low mass-flow conditions, a design of bio-inspired steam turbine blades with biomimetic bumps on the suction side was proposed. Numerical simulation results showed that the bumps generated streamwise vortices, leading to a decrease in pressure on the suction side of the blade. This resulted in improved performance, reflected in the increased output torque.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2022)
Article
Materials Science, Multidisciplinary
Ronghui Guo, Lipeng Wu, Jiaoyan Shi, Fan Wu, Aming Xie
Summary: In this study, hollow polypyrrole nanorods were successfully prepared and the dielectric constant could be adjusted by tuning the wall thickness, resulting in improved electromagnetic wave absorption performance. The minimum reflection loss reached -54.94 dB and the largest effective absorption bandwidth was 7.36 GHz.
Article
Cell Biology
Yingdan Wang, Xiang Zhang, Yunping Ma, Yanqun Wang, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun, Jincun Zhao, Fan Wu, Zhenguo Chen, Jinghe Huang
Summary: This study explores the possibility of combating Omicron and BA.2 by constructing bispecific antibodies based on non-Omicron neutralizing antibodies. The results show that 8 out of 10 bispecific antibodies exhibit high binding affinities to Omicron and BA.2, as well as other SARS-CoV-2 variants. Six of these antibodies also neutralize other sarbecoviruses. Mapping analysis reveals that these bispecific antibodies can accommodate mutations resistant to non-Omicron neutralizing antibodies.
Article
Materials Science, Multidisciplinary
Mengxiao Sun, Xu Lu, Han Gao, Long Qin, Chaochan Chen, Fan Wu, Dafeng Chen
Summary: Melamine foam was converted into porous carbon and composited with rGO and Ni chains to form composites. The composites exhibited improved electrical conductivity and impedance matching ability, and showed good wave-absorbing properties. They can be widely used in the field of electromagnetic wave absorption.
Article
Computer Science, Information Systems
Yuben Qu, Dongyu Lu, Haipeng Dai, Haisheng Tan, Shaojie Tang, Fan Wu, Chao Dong
Summary: This paper studies the problem of resilient service provisioning for edge computing, aiming to determine a service placement strategy to maximize overall utility in the presence of uncertain service failures. Two novel solutions are proposed for the general and homogeneous case, respectively, achieving constant approximation ratio within polynomial time and better approximation ratio than previous methods. Extensive simulations and field experiments validate the effectiveness of the proposed algorithms.
IEEE INTERNET OF THINGS JOURNAL
(2023)
Article
Computer Science, Information Systems
Qinya Li, Zun Li, Zhenzhe Zheng, Fan Wu, Shaojie Tang, Zhao Zhang, Guihai Chen
Summary: With the fast-growing market demand, more and more IoT data is being traded online in cloud-based data marketplaces. However, data consumers face difficulties in making purchasing decisions due to uncertain data quality and inflexible pricing interface. To address these issues, potential solutions include launching data demonstrations and releasing free sampling data to reduce uncertainty about data quality, and implementing flexible pricing based on the volume of data used. The economic benefits of these mechanisms are not yet clear. In this paper, we design optimal data selling mechanisms for IoT data exchange and derive two main findings based on theoretical analysis and evaluation on a real-world Taxi GPS dataset.
IEEE TRANSACTIONS ON MOBILE COMPUTING
(2023)
Article
Virology
Tingting Sun, Yingdan Wang, Peng Zou, Qimin Wang, Jiangyan Liu, Wanli Liu, Jinghe Huang, Fan Wu
Summary: The study constructed three different variants of M2e-specific monoclonal antibodies and found that IgG2a variant provided better protection against influenza virus. Additionally, the administration route and timing of administration were critical factors in determining the protective efficacy.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Engineering, Civil
Muhammad Asad Saleem, Xiong Li, Muhammad Faizan Ayub, Salman Shamshad, Fan Wu, Haider Abbas
Summary: The popularity of vehicles has led to the development of smart cities, making vehicular ad-hoc network (VANET) a widely used communication method for obtaining information about road conditions, speed, vehicle location, and traffic congestion. However, the security of private data in VANET is a critical task due to various security threats. In this article, a lightweight and secure privacy-preserving key agreement protocol for VANETs is proposed, which utilizes hashing technique for efficient and secure data transmission.
IEEE TRANSACTIONS ON INTELLIGENT TRANSPORTATION SYSTEMS
(2023)
Article
Chemistry, Physical
Junru Yao, Jintang Zhou, Feng Yang, Guiyu Peng, Yijie Liu, Zhengjun Yao, Fan Wu, Haibo Zeng
Summary: The development of multifunctional materials and the integration of various functions are crucial for integrated and miniaturized equipment. In this study, asymmetric MXene/aramid nanofibers/polyimides (AMAP) aerogels were developed through an integrated molding process. The clever asymmetry of these aerogels allows for enhanced performances, such as low reflection electromagnetic interference (EMI) shielding, high-efficiency infrared radiation stealth, and excellent thermal management performances. These multifunctional AMAP aerogels have potential applications in electromagnetic pollution protection, insulation, and military equipment protection against infrared detection and EMI.
Review
Materials Science, Multidisciplinary
Jing Qiao, Lutong Li, Jiurong Liu, Na Wu, Wei Liu, Fan Wu, Zhihui Zeng
Summary: Rare earth plays a crucial role in electromagnetic wave absorption materials, and the strategies of doping rare earth elements and constructing rare earth oxide composites are important for the fabrication of high-efficiency electromagnetic wave absorption materials. This review provides a comprehensive summary of the research background, classification, features, progress, and future development of rare earth electromagnetic wave absorption materials, offering guidance for future development.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2024)
Letter
Cell Biology
Yingdan Wang, Wuqiang Zhan, Jiangyan Liu, Yanqun Wang, Xiang Zhang, Meng Zhang, Lin Han, Yunping Ma, Lu Lu, Yumei Wen, Zhenguo Chen, Jincun Zhao, Fan Wu, Lei Sun, Jinghe Huang
Article
Medicine, Research & Experimental
Bing Yang, Zhen Zhang, Xiangjun Chen, Xu-Yan Wang, Shishang Qin, Liaoqi Du, Changjiang Yang, Liyu Zhu, Wenbo Sun, Yongjie Zhu, Qinwen Zheng, Shidong Zhao, Quan Wang, Long Zhao, Yilin Lin, Jinghe Huang, Fan Wu, Lu Lu, Fei Wang, Wenjie Zheng, Xiao-Hua Zhou, Xiaozhen Zhao, Ziye Wang, Sun Xiao-Lin, Yingjiang Ye, Shan Wang, Zhanguo Li, Hai Qi, Zemin Zhang, Dong-Ming Kuang, Lei Zhang, Zhanlong Shen, Wanli Liu
Summary: A variant of human IgG1 specific to Asia has been found to improve survival of colorectal cancer patients. This variant enhances the differentiation of tumor-associated antigen-specific plasma cells and antibody production, leading to improved phagocytosis of tumor cells and presentation to CD8' T cells. Transplantation of memory B cells with this variant has shown therapeutic efficacy in mouse tumor models.
JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Materials Science, Multidisciplinary
Zhiheng Huang, Yanchong Zhao, Tao Bo, Yanbang Chu, Jinpeng Tian, Le Liu, Yalong Yuan, Fanfan Wu, Jiaojiao Zhao, Lede Xian, Kenji Watanabe, Takashi Taniguchi, Rong Yang, Dongxia Shi, Luojun Du, Zhipei Sun, Sheng Meng, Wei Yang, Guangyu Zhang
Summary: In this study, three types of spatially indirect excitons and their quantum-confined Stark effects in bilayer WSe2 were discovered through electric field-tunable photoluminescence measurements. It was demonstrated, through first-principles calculations, that these excitons are momentum indirect and exhibit highly tunable circular polarization.
