Article
Agricultural Engineering
Giuditta C. Heinzl, Danyelle A. Mota, Valentina Martinis, Ana Sofia Martins, Cleide M. F. Soares, Natalia Osorio, Jorge Gominho, K. Madhavan Nampoothiri, Rajeev K. Sukumaran, Helena Pereira, Suzana Ferreira-Dias
Summary: This study investigates the direct utilization of high acidic olive pomace oil (OPO) to produce added-value compounds using lipases. The results demonstrate the successful production of low-calorie dietetic structured lipids, biodiesel, and emulsifiers from OPO. The immobilized Rhizomucor miehei lipase shows high activity in acidolysis and interesterification, with minimal impact from OPO acidity. Complete conversion of OPO into fatty acid methyl esters and sn-2 monoacylglycerols is achieved through transesterification, with negligible lipase deactivation after multiple cycles.
BIORESOURCE TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Xiaozhong Chen, Shangde Sun
Summary: During the transport, storage, and consumption of edible vegetable oils, the issue of color reversion, where the color of freshly refined oils darkens, has plagued the oil industry for a long time due to its association with poor quality and low consumer acceptability. This paper provides a brief overview of oil color and the research progress on the mechanism of color reversion, with a focus on the effect of minor components (phospholipids and metal ions) and measures to restrain color reversion through quality control, processing parameter adjustment, and storage conditions.
Article
Biochemistry & Molecular Biology
Shanxiu Ming, Shuyi Li, Zhe Chen, Xujun Chen, Feifei Wang, Shaonan Deng, Krystian Marszalek, Zhenzhou Zhu, Wenxiang Zhang, Francisco J. Barba
Summary: Traditional enzymatic esterification methods have limitations in improving the bioavailability of flavonoids, while the novel BLIMs technology shows great potential in enhancing compound utilization. Among the three BLIMs, GA/CAL-B@PDA/PES performs the best with high enzyme activity and loading, as well as stable performance under various environmental conditions.
Article
Chemistry, Applied
Paula S. Mateos, Marisa B. Navas, Susana R. Morcelle, Claudia Ruscitti, Silvana R. Matkovic, Laura E. Briand
Summary: The study focused on investigating the biocatalytic performance of a lipase obtained from Araujia sericifera latex in hydrolysis and esterification reactions with sunflower waste cooking oil. The results showed that the lipase had high enzymatic activity in hydrolyzing and esterifying the oil, with over 90% conversion of free fatty acids achieved using short chain alcohols.
Article
Food Science & Technology
Jinhang Chen, Yi Zhang, Huaying Zhong, Hao Zhu, Hongxun Wang, Kheng-Lim Goh, Juntao Zhang, Mingming Zheng
Summary: In this study, an immobilized lipase microarray (CSL@OMS-C-8) was prepared for the green and effective synthesis of flavor esters. The CSL@OMS-C-8 exhibited a higher catalytic activity than free lipase and achieved a record-breaking yield of benzyl cinnamate. The immobilized lipase also demonstrated high stability and reusability, as well as broad applicability in synthesizing different cinnamic esters.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Galina Kovalenko, Larisa Perminova, Anatoly Beklemishev
Summary: Heterogeneous biocatalysts prepared by immobilizing recombinant lipases show promise for organic synthesis of various esters. The reaction rates of esterification strongly depend on the selected pair of lipase substrates and the polarity of the organic solvent used. The prepared lipase-active biocatalysts exhibited high operational stability under optimal reaction conditions.
Article
Food Science & Technology
Namhyeon Park, Marie K. Walsh
Summary: This study found that maltodextrin fatty acid esters synthesized from maltodextrin with a lower dextrose equivalent have higher microbial inhibitory activity compared to commercial sucrose laurate, indicating potential application in foods. Microbes sensitive to both SL and MFAs showed damaged cell membranes and morphological deformations.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Food Science & Technology
Fataneh Hashempour-Baltork, Parastou Farshi, Adel Mirza Alizadeh, Sodeif Azadmard-Damirchi, Mohammadali Torbati
Summary: With the growing interest in nutritional properties and bioactive components of foods, there is an increase in consumption of vegetable oils, both refined and unrefined. However, the refining process can lead to the removal of beneficial components and the formation of harmful ones, which can cause serious health issues. On the other hand, virgin oils have been found to have positive effects on gut microbiota, nervous system, and overall health, making their inclusion in the diet highly recommended.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
(2022)
Article
Energy & Fuels
Yamini Satyawali, Lieve Cauwenberghs, Miranda Maesen, Winnie Dejonghe
Summary: This work presents a practical comparison of simple reaction systems for enzymatic production of MAG, focusing on water removal strategies and product selectivity. High fatty acid conversion was achieved in all reactor systems, with product composition and selectivity influenced by reaction conditions and setups. The study demonstrated the practical applicability of packed bed reactor coupled with pervaporation for enzyme reuse and in situ water removal using zeolite based membranes.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2021)
Article
Agriculture, Multidisciplinary
Wenyi Chen, Lihong He, Wenzhu Song, Jianrong Huang, Nanjing Zhong
Summary: Most of the encapsulated lipases exhibited moderate and considerable glycerolysis activity. In addition, AOL@GMP/Tb, TLL@GMP/Tb, RML@GMP/Tb, and CALA@GMP/Tb exhibited good reusability in glycerolysis reactions and potential in practical applications.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Engineering, Environmental
Batoul Mohebrad, Ghazaleh Ghods, Abbas Rezaee
Summary: This study found that immobilizing Pseudomonas aeruginosa on calcium alginate and stimulating the bacteria with electricity can increase the production of protease and lipase, thus reducing the treatment time for dairy wastewater in a microbial electrochemical system.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Food Science & Technology
Sandra Martin-Torres, Antonio Gonzalez-Casado, Miriam Medina-Garcia, Maria Soledad Medina-Vazquez, Luis Cuadros-Rodriguez
Summary: The stability of highly consumed vegetable refined oils after discontinuous frying of potatoes was compared. Both those vegetable oils containing additives and those that did not were considered. Chemical changes caused over the frying time were monitored and multivariate modelling of the data was carried out. A new gas chromatographic-mass spectroscopy method was intended to record a fingerprint of both polar and non-polar compound fractions, and the results obtained from both approaches were verified to be statistically similar.
Article
Chemistry, Physical
Azhar A. Najjar, Elhagag A. Hassan, Nidal M. Zabermawi, Saad B. Almasaudi, Mohammed Moulay, Steve Harakeh, Mohamed Abd El-Aal
Summary: This study successfully converted cooking oil wastes into biodiesel using immobilized lipase on Fe3O4/cellulose nanocomposite, demonstrating improved stability and reusability of the catalyst. The produced biodiesel met the standards and can be utilized as diesel fuel in daily life.
Article
Food Science & Technology
Helena Sovova
Summary: The stereospecific composition of triacylglycerols (TAGs) in genetically modified sunflower and soybean seed oils was calculated using various mathematical models, with the DAG-random, 3-random model showing potential to better reflect the composition of TAGs rich in polyunsaturated fatty acids. This model considers acyl editing in the phosphatidylcholine pool of seed cells, unlike simpler models that correspond to the Kennedy pathway of oil biosynthesis.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Chemical
Zhen Chen, Huan-Yin Xie, Gui-E Chen, Sun-Jie Xu, Zhen-Liang Xu, Yi-Jing Li, Hai-Fang Mao
Summary: The novel CALB@VLS/PMIA membranes exhibited excellent separation and biocatalysis performance, with enhanced efficiency in catalyzing the synthesis of esters. The membranes have great potential for broad applications in various fields due to their superior catalytic capabilities.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Plant Sciences
Emilia Cavo, Maria Fernanda Taviano, Vivienne Spadaro, Francesco Maria Raimondo, Francesco Cacciola, Yassine Oulad El Majdoub, Luigi Mondello, Federica Davi, Concetta Condurso, Fabrizio Cincotta, Antonella Verzera, Natalizia Miceli
Summary: This study investigated the specific and intraspecific taxa of Matthiola growing in Sicily, with a focus on Matthiola tricuspidata and Matthiola sinuata. The phenolic and volatile compounds of the aerial parts of these species were characterized, and their antioxidant capacity and toxicity were evaluated. The results showed that both M. tricuspidata and M. sinuata are new safe sources of bioactive compounds with antioxidant potential.
Article
Food Science & Technology
Imad Kabach, Najat Bouchmaa, Reda Ben Mrid, Zakia Zouaoui, Mohammed El Maadoudi, Ayoub Kounnoun, Fadoua Asraoui, Fouad El Mansouri, Abdelmajid Zyad, Francesco Cacciola, Yassine Oulad El Majdoub, Luigi Mondello, Mohamed Nhiri
Summary: This study investigated the phytochemical composition, antioxidant properties, antidiabetic potential, and cytotoxicity of Olea europaea var. oleaster (Oeo) fruit. The results showed that Oeo fruit contains high levels of phenolic and flavonoid compounds and exhibits strong antioxidant activity. Methanolic extract demonstrated better antioxidant activity than aqueous extract and showed inhibitory effects on glycation and breast cancer cells.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Chemistry, Applied
Mustapha Cherrate, Reda EL-Mernissi, Aziz Bouymajane, Fouzia Rhazi Filali, Emanuela Trovato, Ghizlane Echchgadda, Abdellah Maissour, Mohammed Aziz Ajana, Paola Dugo, Francesco Cacciola, Luigi Mondello, Kacem Makroum
Summary: The study focused on characterizing the chemical composition and assessing the antioxidant and antibacterial activities of Ziziphora hispanica essential oil (ZH-EO) from the Middle Atlas of Morocco (Boulmane). Results showed that ZH-EO consisted of 119 volatile components, representing 88.7% of the total oil. ZH-EO exhibited bactericidal and bacteriostatic effects against various bacteria and demonstrated strong antioxidant activity. ADMET prediction indicated favorable pharmacokinetic properties of the tested components. This study suggests that Ziziphora hispanica essential oil could be a potential source of bioactive molecules for preventing diseases related to oxidative stress and pathogenic bacteria.
JOURNAL OF ESSENTIAL OIL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Nadia Naim, Aziz Bouymajane, Yassine Oulad El Majdoub, Said Ezrari, Rachid Lahlali, Abdessalem Tahiri, Said Ennahli, Roberto Lagana Vinci, Francesco Cacciola, Luigi Mondello, Ilham Madani
Summary: This study investigates the phenolic composition and antibacterial properties of hydroethanolic extracts from Crocus sativus L. petals collected in Serghina, Morocco. The extracts were found to contain 27 phenolic compounds, with the most abundant being kaempferol-sophoroside isomer. The extracts showed bactericidal effects against Staphylococcus aureus and Listeria monocytogenes, and bacteriostatic effects against Escherichia coli and Salmonella typhimurium. These findings suggest that Crocus sativus L. petal extracts could be valuable sources of natural antibacterial agents for the food and pharmaceutical industries.
Article
Chemistry, Multidisciplinary
Ibtissam Elaaraj, Najia Moukrad, Aziz Bouymajane, Safae Er Raouan, Asmae Nakkabi, Oumayma Oulidi, Fouzia Rhazi Filai, Ibnsouda Koraichi Saad, Francesco Cacciola, Noureddine El Moualij, Mohammed Fahim
Summary: New cobalt(II), nickel(II), copper(II), and zinc(II) complexes based on a tetradentate ligand were synthesized and characterized. The complexes exhibited different geometries, and the copper(II) complex showed the highest antibacterial activity. The ligand and complexes were also evaluated for their biological effects on seed germination, immune cells, and blood cells.
RESULTS IN CHEMISTRY
(2023)
Article
Biochemical Research Methods
Tania M. G. Salerno, Emanuela Trovato, Giovanna Cafeo, Federica Vento, Mariosimone Zoccali, Paola Donato, Paola Dugo, Luigi Mondello
Summary: During the Covid-19 pandemic, it was found that some citrus-scented hand gels did not meet the labeling requirements for fragrance allergens, and their furocoumarin content exceeded the safe limits. Additionally, some products did not match the information reported on the label regarding the presence of essential oils. Therefore, urgent development of analytical tools and regulatory actions for widespread testing of hand hygiene products is needed to ensure consumer health and safety.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Medicine, Research & Experimental
Imad Kabach, Najat Bouchmaa, Zakia Zouaoui, Abdelhamid Ennoury, Sara El Asri, Abdelmounaim Laabar, Loubna Oumeslakht, Francesco Cacciola, Yassine Oulad El Majdoub, Luigi Mondello, Abdelmajid Zyad, Naima Nhiri, Mohamed Nhiri, Reda Ben Mrid
Summary: The study aimed to evaluate the antioxidant and antidiabetic properties of Oxalis pes-caprae flowers extract in alloxan-induced diabetic mice. Results showed that the extract exhibited significant antioxidant and antidiabetic activity by reducing blood glucose levels and increasing the activities of antioxidants and glycolysis enzymes.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Paola Arena, Natalizia Miceli, Andreana Marino, Federica Davi, Emilia Cavo, Vivienne Spadaro, Francesco Maria Raimondo, Francesco Cacciola, Roberto Lagana Vinci, Luigi Mondello, Maria Fernanda Taviano
Summary: This study aimed to explore Sinapis pubescens subsp. pubescens as a new potential source of active metabolites. Comparative analysis was conducted on the hydroalcoholic extracts of the leaf, flower, and stem. Polyphenols in the extracts were quantitatively determined and characterized, revealing significant differences in their profiles. The extracts exhibited antioxidant activity, with the leaf extract showing the best radical scavenging activity and the flower extract demonstrating the highest chelating activity. However, no antimicrobial activity was observed in the strains tested. Moreover, the extracts were found to be non-toxic. The aerial parts of S. pubescens subsp. pubescens could serve as valuable sources of antioxidants for pharmaceutical and nutraceutical applications.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Biochemistry & Molecular Biology
Federica Davi, Maria Fernanda Taviano, Rosaria Acquaviva, Giuseppe Antonio Malfa, Emilia Cavo, Paola Arena, Salvatore Ragusa, Francesco Cacciola, Yassine Oulad El Majdoub, Luigi Mondello, Natalizia Miceli
Summary: Our research team conducted a study on Brassica fruticulosa subsp. fruticulosa, an edible plant used for treating various ailments. We found that the leaf extract exhibited good antioxidant properties, with the secondary compounds being more potent than the primary ones. Further investigation revealed that the phenolic compounds in the extract possessed antioxidant properties and inhibited the proliferation of human colorectal epithelial adenocarcinoma cells.
Article
Food Science & Technology
Ahlem Eddehech, Renaud Rahier, Danilo Donnarumma, Francesca Rigano, Alexandre Noiriel, Abdelkarim Abousalham, Francesco Cacciola, Luigi Mondello, Zied Zarai
Summary: This study presents the expression and characterization of a novel phosphatidylinositol phospholipase C (PI-PLCBt) from Bacillus thuringiensis PL14, which shows potential for oil degumming. Enzymatic degumming tests were conducted on crude soybean oil using rPI-PLCBt, and its efficiency was evaluated by measuring phosphorus and diacylglycerol (DAG) contents after different treatments. The results showed that enzymatic degumming achieved a high efficiency of 89.4%, reducing phosphorus content to 13.7 mg kg-1 and increasing DAG levels. This suggests that enzymatic degumming could be a more efficient and environmentally friendly alternative to traditional degumming methods, while also enhancing the nutritional value of the final product.
Article
Integrative & Complementary Medicine
Csongor Bako, Viktoria Lilla Balazs, Erika Kerekes, Bela Kocsis, David U. Nagy, Peter Szabo, Giuseppe Micalizzi, Luigi Mondello, Judit Krisch, Dora Petho, Gyorgyi Horvath
Summary: Thyme essential oil is popular due to its antimicrobial effect, but the chemical composition of the oil influences its biological activity. This study investigates the influence of flowering phenophases on the chemical composition, antibacterial and anti-biofilm activity of Thymus vulgaris essential oil, finding that the collection time has important implications for its activity.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2023)
Article
Chemistry, Applied
Natalia Manousi, Antonio Ferracane, Natasa P. Kalogiouri, Abuzar Kabir, Kenneth G. Furton, Peter Q. Tranchida, George A. Zachariadis, Luigi Mondello, Victoria F. Samanidou, Erwin Rosenberg
Summary: In this study, sol-gel sorbent-coated second-generation fabric phase sorptive extraction (FPSE) membranes were synthesized using titania-based sol-gel precursors. These membranes showed high efficiency in extracting organophosphorus pesticides from apple juice samples. The optimized FPSE method using these membranes demonstrated good accuracy in analysis and the novel membranes were reusable up to 5 times. Comparatively, the titania-based membranes provided higher extraction recoveries than conventional silica-based membranes.
Article
Materials Science, Biomaterials
Fadoua Asraoui, Fouad El Mansouri, Francesco Cacciola, Jamal Brigui, Adnane Louajri, Giovanna Simonetti
Summary: This study investigates the antifungal and antibiofilm activity of Inula viscosa and Globularia alypum leaf extracts against Candida, both in vitro and in vivo. The extracts show fungicidal activity and are capable of preventing biofilm development. In vivo tests on Galleria mellonella larvae demonstrate that the extracts increase the survival rate of larvae infected with Candida. These findings suggest that I. viscosa and G. alypum extracts could be considered as potential antifungal agents and biofilm inhibitors in pharmaceutical and agro-food fields.
