Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting the Effects of Anti-FcRn Therapy on the Disposition of Endogenous IgG in Humans

Title
Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting the Effects of Anti-FcRn Therapy on the Disposition of Endogenous IgG in Humans
Authors
Keywords
FcRn, antibody FcRn inhibitor, PBPK model
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 108, Issue 1, Pages 714-724
Publisher
Elsevier BV
Online
2018-11-22
DOI
10.1016/j.xphs.2018.10.067

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