4.7 Article

Ag-Mediated Trifluoromethylthiolation of Inert Csp(3)-H Bond

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 83, Issue 22, Pages 14120-14125

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b02207

Keywords

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Funding

  1. National Basic Research Program of China [2015CB931903]
  2. National Natural Science Foundation [21421002, 21472222, 21502214, 21672242]
  3. Chinese Academy of Sciences [XDA02020105, XDA02020106]
  4. Key Research Program of Frontier Sciences (CAS) [QYZDJ-SSW-SLH049]

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Ag-mediated trifluoromethylthiolation of inert Csp(3)-H bond with CF3SOCl is described. Widely available reagents and operational simplicity make this protocol attractive.

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