Journal
BIOCHEMISTRY-MOSCOW
Volume 80, Issue 11, Pages 1457-1464Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297915110061
Keywords
mitochondria; fusion; fission
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Funding
- Federal Center Program [14.604.21.0113, RFME-FI60414X0113]
- Russian Foundation for Basic Research [15-04-00378]
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Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria. On the other hand, it has been shown that these events are of great biological importance for functioning of living cells. In this review, we summarize existing molecular data on mitochondrial dynamics and discuss possible biological functions of fusion and fission of these organelles.
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