HERV-W env regulates calcium influx via activating TRPC3 channel together with depressing DISC1 in human neuroblastoma cells

Syncytin-1, an endogenous retroviral protein, triggers the activation of CRP via TLR3 signal cascade in glial cells

(2018) Xiuling Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Genetic Determinants of Antibody Levels in Cerebrospinal Fluid in Multiple Sclerosis: Possible Links to Endogenous Retroviruses

(2018) Alexander Emmer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human Endogenous Retroviruses in Neurological Diseases

(2018) Patrick Küry et al.   TRENDS IN MOLECULAR MEDICINE

Investigation of Endogenous Retrovirus Sequences in the Neighborhood of Genes Up-regulated in a Neuroblastoma Model after Treatment with Hypoxia-Mimetic Cobalt Chloride

(2018) Christine Brütting et al.   Frontiers in Microbiology

HERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors

(2018) Norbert Bannert et al.   Frontiers in Microbiology

HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity

(2018) Nicole Grandi et al.   Frontiers in Microbiology

HBV X Protein induces overexpression of HERV-W env through NF-κB in HepG2 cells

(2017) Cong Liu et al.   VIRUS GENES

Human endogenous retrovirus W env increases nitric oxide production and enhances the migration ability of microglia by regulating the expression of inducible nitric oxide synthase

(2017) Ran Xiao et al.   VIROLOGICA SINICA

Human leukemia antigen-A*0201-restricted epitopes of human endogenous retrovirus W family envelope (HERV-W env) induce strong cytotoxic T lymphocyte responses

(2017) Xiaoning Tu et al.   VIROLOGICA SINICA

The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis

(2017) Elena Morandi et al.   PLoS One

Expression and function of endogenous retroviruses in the placenta

(2016) Joachim Denner   APMIS

Elevation of Ser9 phosphorylation of GSK3β is required for HERV-W env-mediated BDNF signaling in human U251 cells

(2016) Chengchen Qin et al.   NEUROSCIENCE LETTERS

Discovery of unfixed endogenous retrovirus insertions in diverse human populations

(2016) Julia Halo Wildschutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Classification and characterization of human endogenous retroviruses; mosaic forms are common

(2016) Laura Vargiu et al.   Retrovirology

Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K–Related Sequences

(2015) Rafael Contreras-Galindo et al.   JOURNAL OF VIROLOGY

Inflammation in schizophrenia: A question of balance

(2015) Juan C. Leza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Adult cortical plasticity depends on an early postnatal critical period

(2015) S. D. Greenhill et al.   SCIENCE

Human endogenous retrovirus-K contributes to motor neuron disease

(2015) Wenxue Li et al.   Science Translational Medicine

ERVK Polyprotein Processing and Reverse Transcriptase Expression in Human Cell Line Models of Neurological Disease

(2015) Mamneet Manghera et al.   Viruses-Basel

Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics

(2015) Sung Jin Park et al.   Scientific Reports

Peripheral DISC1 protein levels as a trait marker for schizophrenia and modulating effects of nicotine

(2014) Svenja V. Trossbach et al.   BEHAVIOURAL BRAIN RESEARCH

Disrupted in Schizophrenia 1 Modulates Medial Prefrontal Cortex Pyramidal Neuron Activity Through cAMP Regulation of Transient Receptor Potential C and Small-Conductance K+ Channels

(2014) Lynda El-Hassar et al.   BIOLOGICAL PSYCHIATRY

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Human endogenous retroviruses and cancer prevention: evidence and prospects

(2013) Luca Cegolon et al.   BMC CANCER

Nitric oxide-induced calcium release

(2013) Sho Kakizawa et al.   Channels

Human endogenous retrovirus W family envelope gene activates the small conductance Ca2+-activated K+ channel in human neuroblastoma cells through CREB

(2013) S. Li et al.   NEUROSCIENCE

Mutations in 3′-long terminal repeat of HERV-W family in chromosome 7 upregulate syncytin-1 expression in urothelial cell carcinoma of the bladder through interacting with c-Myb

(2013) H Yu et al.   ONCOGENE

Human Endogenous Retrovirus Protein Activates Innate Immunity and Promotes Experimental Allergic Encephalomyelitis in Mice

(2013) Hervé Perron et al.   PLoS One

Activation of elements in HERV-W family by caffeine and aspirin

(2013) Chunlan Liu et al.   VIRUS GENES

The histone variant MacroH2A regulates Ca2+ influx through TRPC3 and TRPC6 channels

(2013) J-M Kim et al.   Oncogenesis

Calcium signalling remodelling and disease

(2012) Michael J. Berridge   BIOCHEMICAL SOCIETY TRANSACTIONS

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

(2011) Junyi Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A CAG repeat polymorphism ofKCNN3predicts SK3 channel function and cognitive performance in schizophrenia

(2011) Sabrina Grube et al.   EMBO Molecular Medicine

Lack of Kinase Regulation of Canonical Transient Receptor Potential 3 (TRPC3) Channel-dependent Currents in Cerebellar Purkinje Cells

(2011) Charmaine Nelson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mGluR1/TRPC3-mediated Synaptic Transmission and Calcium Signaling in Mammalian Central Neurons

(2011) J. Hartmann et al.   Cold Spring Harbor Perspectives in Biology

Metabolome in schizophrenia and other psychotic disorders: a general population-based study

(2011) Matej Orešič et al.   Genome Medicine

Implication of the env Gene of the Human Endogenous Retrovirus W Family in the Expression of BDNF and DRD3 and Development of Recent-Onset Schizophrenia

(2010) W. Huang et al.   SCHIZOPHRENIA BULLETIN

Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development

(2009) N. J. Brandon et al.   JOURNAL OF NEUROSCIENCE

TRPC3 Channels Are Required for Synaptic Transmission and Motor Coordination

(2008) Jana Hartmann et al.   NEURON