Regulation of cyclooxygenase 2 expression by agonists of PPAR nuclear receptors in the model of endotoxin tolerance in astrocytes

Neuroinflammation in Alzheimer's Disease: Are NSAIDs and Selective COX-2 Inhibitors the Next Line of Therapy?

(2017) Catherine H. Trepanier et al.   JOURNAL OF ALZHEIMERS DISEASE

Regulation of peroxisome proliferator-activated receptor β/δ expression and activity levels by toll-like receptor agonists and MAP kinase inhibitors in rat astrocytes

(2014) Dmitry V. Chistyakov et al.   JOURNAL OF NEUROCHEMISTRY

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma

(2013) Irene Paterniti et al.   Journal of Neuroinflammation

Peroxisome proliferator-activated receptor (PPAR)β/δ, a possible nexus of PPARα- and PPARγ-dependent molecular pathways in neurodegenerative diseases: Review and novel hypotheses

(2013) Stepan Aleshin et al.   NEUROCHEMISTRY INTERNATIONAL

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA in TLR signaling and endotoxin tolerance

(2011) Md A Nahid et al.   Cellular & Molecular Immunology

Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells

(2011) O. M. Pena et al.   JOURNAL OF IMMUNOLOGY

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

(2011) Keri B Vartanian et al.   Journal of Neuroinflammation

Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1  and TNF: Implications for Neuropathic Pain

(2011) S. Nadeau et al.   JOURNAL OF NEUROSCIENCE

HDAC6 Regulates LPS-Tolerance in Astrocytes

(2011) Eléonore Beurel   PLoS One

Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice

(2011) Amit Gupta et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

Resolution of Inflammation in Murine Autoimmune Arthritis Is Disrupted by Cyclooxygenase-2 Inhibition and Restored by Prostaglandin E2-Mediated Lipoxin A4 Production

(2010) M. M. Y. Chan et al.   JOURNAL OF IMMUNOLOGY

PPAR activation has dichotomous control on the expression levels of cytosolic and secretory phospholipase A2 in astrocytes; inhibition in naïve, untreated cells and enhancement in LPS-stimulated cells

(2010) Marina G. Sergeeva et al.   JOURNAL OF NEUROCHEMISTRY

Glycogen synthase kinase-3 regulates inflammatory tolerance in astrocytes

(2010) E. Beurel et al.   NEUROSCIENCE

Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use

(2009) Ulrich Dirnagl et al.   LANCET NEUROLOGY

Peroxisome Proliferator-Activated Receptor (PPAR)-  Positively Controls and PPAR  Negatively Controls Cyclooxygenase-2 Expression in Rat Brain Astrocytes through a Convergence on PPAR /  via Mutual Control of PPAR Expression Levels

(2009) S. Aleshin et al.   MOLECULAR PHARMACOLOGY

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2

(2008) Saba Aid et al.   Journal of Neuroinflammation

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY