Review
Agriculture, Dairy & Animal Science
Achraf Benammar, Emilie Derisoud, Francois Vialard, Eric Palmer, Jean Marc Ayoubi, Marine Poulain, Pascale Chavatte-Palmer
Summary: Horses serve as a potential animal model for researching artificial reproduction techniques, despite significant differences in reproductive anatomy and processes with humans. However, similarities are found in embryo development and certain reproductive phenomena. Both species share common concerns related to infertility.
Article
Reproductive Biology
Lachlan G. Howell, Ryan R. Witt
Summary: Assisted reproductive technologies (ARTs) have the potential to contribute significantly to the conservation of endangered wildlife, such as the koala. However, the lack of funding hinders the application of ARTs in koalas and other wildlife. It is important to raise public awareness and secure funding for the development of ARTs.
Article
Veterinary Sciences
Effrosyni Fatira, Milos Havelka, Taiju Saito, Jose Landeira, Marek Rodina, David Gela, Martin Psenicka
Summary: In this study, the researchers applied intracytoplasmic sperm injection (ICSI) technology to endangered sturgeons and found that it successfully produced embryos and larvae. Furthermore, molecular analysis showed genome integration of both egg and sperm donor species, demonstrating the potential of ICSI for assisted reproduction in sturgeons.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Agriculture, Dairy & Animal Science
Carolina Acevedo, Jennifer P. Barfield
Summary: To conserve the important species of bison in Europe and North America, conservation efforts have focused on establishing sustainable herds through the use of assisted reproductive technologies (ARTs). These technologies facilitate the transfer of genetics and offer protection against future losses of genetic diversity. Research on ART for bison has made progress, but there are still opportunities for improvement and expanding their impact on bison conservation.
Review
Agriculture, Dairy & Animal Science
Carolina Acevedo, Jennifer P. Barfield
Summary: Bison are important species ecologically and culturally, and conservation efforts are focused on building sustainable herds using assisted reproductive technologies. This review discusses the current state of ART in American bison and European bison, highlighting the potential for genetic conservation and the need for further improvement and expansion of these technologies.
Article
Multidisciplinary Sciences
Madara S. B. Ralapanawe, Sugandika L. Gajaweera, Nishendra Karunaratne, Vajira H. W. Dissnayake, Malcolm J. Price, Pedro Melo, Arri Coomarasamy, Ioannis D. Gallos
Summary: Recent studies have suggested an association between chromosomal polymorphic variations and infertility, with higher rates of miscarriage found in assisted reproduction. This study aims to analyze the influence of specific types or number of chromosomal polymorphic variations on reproductive outcomes in couples undergoing ICSI treatment. The analysis of data from 929 fresh and frozen embryo transfer cycles of 692 women revealed no significant difference in reproductive outcomes based on carriers or non-carriers of chromosomal polymorphic variations. Further studies are needed to determine whether detecting these variations before assisted conception is a useful diagnostic tool.
SCIENTIFIC REPORTS
(2023)
Article
Obstetrics & Gynecology
Nicole Lustgarten Guahmich, Elena Borini, Nikica Zaninovic
Summary: Artificial intelligence has been utilized in assisted reproductive technology to potentially improve success rates. Algorithms that track and rank individual sperm in real-time have been developed, but further research is needed to determine their clinical benefits in improving pregnancy rates.
FERTILITY AND STERILITY
(2023)
Article
Endocrinology & Metabolism
Yubin Li, Qiyuan Chang, Qingyun Mai
Summary: This retrospective cohort study investigated the incidence, pregnancy and neonatal outcomes of monozygotic twins (MZTs) following assisted reproductive technology (ART) treatments, including IVF, ICSI, PGT, and TESA. The study found that the rate of MZTs was similar among the four ART groups, but the IVF group had a higher risk of pregnancy loss and early miscarriage, while the TESA group had a higher risk of twin-to-twin transfusion syndrome (TTTS).
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Koray Gok, Selcuk Ozden
Summary: A study compared the size of fetal thymus in ART or naturally conceived pregnancies. It was found that the fetal thymus was smaller in ART pregnancies, as indicated by both fetal thymic-thoracic ratio and fetal thymus transverse diameter values.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Review
Genetics & Heredity
Veena Unnikrishnan, John Kastelic, Jacob Thundathil
Summary: In cattle, the efficiency of ICSI is hindered by failed oocyte activation post sperm injection. Research focusing on proteins like Na/K-ATPase and PLC zeta is key to improving the success rate. Enhancing the efficiency of bovine ICSI has significant implications for the cattle breeding industry.
Review
Medicine, General & Internal
Lauren Lacey, Sibte Hassan, Sebastian Franik, Mourad W. Seif, M. Ahsan Akhtar
Summary: The effects of assisted hatching (AH) on live birth rates are uncertain and may increase the risk of multiple pregnancies. Although AH may offer a slightly increased chance of achieving a clinical pregnancy, the quality of data is low, and it is uncertain whether it influences miscarriage rates.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Medicine, General & Internal
Huixiao Chen, Ping Sun, Na Zhang, Shangge Lv, Yongzhi Cao, Lei Yan
Summary: This study assessed the effect of uterine septum resection on reproductive outcomes in patients with secondary infertility undergoing in vitro fertilization/intracytoplasmic sperm injection. The results showed that uterine septum resection improved the pregnancy rates and live birth rates in these patients.
FRONTIERS IN MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ahmad Aboukhshaba, Nahid Punjani, Sofia Doukakis, Nikica Zaninovic, Gianpiero Palermo, Peter N. Schlegel
Summary: The study aimed to evaluate the impact of sperm characteristics on intracytoplasmic sperm injection (ICSI) outcomes in men with nonobstructive azoospermia (NOA) following microdissection testicular sperm extraction (mTESE). The results showed that specific sperm defects did not completely preclude the chance of clinical pregnancy. This study is the first comprehensive evaluation of the importance of these characteristics in ICSI outcomes.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Yukiko Katagiri, Yuko Tamaki
Summary: Reproductive medicine requires genetic knowledge, including understanding of birth defects, chromosomal abnormalities, Y chromosome microdeletions, chromosomal abnormalities in oligospermia, and epigenetic alterations. Professionals in this field must be well-versed in these areas for successful treatment.
REPRODUCTIVE MEDICINE AND BIOLOGY
(2021)
Article
Obstetrics & Gynecology
Robert John Norman
Summary: Intracytoplasmic sperm injection (ICSI) was initially introduced for male infertility but is now widely used in assisted reproduction techniques. The indications for ICSI use need to be re-evaluated to ensure appropriate application in infertility management.
FERTILITY AND STERILITY
(2022)
Review
Health Care Sciences & Services
Brintha Sivajohan, Mohamed Elgendi, Carlo Menon, Catherine Allaire, Paul Yong, Mohamed A. Bedaiwy
Summary: This review explores the use of AI methods to address clinical problems in endometriosis and finds that AI models have good diagnostic and predictive capacity, offering promising directions for assessing endometriosis.
NPJ DIGITAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Alicia J. Long, Paramdeep Kaur, Alexandra Lukey, Catherine Allaire, Janice S. Kwon, Aline Talhouk, Paul J. Yong, Gillian E. Hanley
Summary: This study aimed to compare the outcomes between those who underwent a hysterectomy for endometriosis with conservation of one or both ovaries and those who underwent a hysterectomy with bilateral salpingo-oophorectomy. The study found that patients who underwent a hysterectomy with bilateral salpingo-oophorectomy had a lower reoperation rate, but there was little difference between the groups in terms of other pain-related health services.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Sarka Lisonkova, Jeffrey N. Bone, Giulia M. Muraca, Neda Razaz, Amelie Boutin, Justin S. Brandt, Mohamed A. Bedaiwy, Cande Ananth, K. S. Joseph
Summary: The closure of ART clinics during the early pandemic resulted in a significant decline in ART-conceived live births and multiple births, as well as an increase in stillbirths among ART-conceived births. Women who conceived during the early pandemic period also had a higher prevalence of obesity and chronic hypertension.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)
Article
Obstetrics & Gynecology
Dwayne R. Tucker, Heather L. Noga, Caroline Lee, Derek S. Chiu, Mohamed A. Bedaiwy, Christina Williams, Catherine Allaire, Aline Talhouk, Paul J. Yong
Summary: A study found that preoperative pelvic pain comorbidities were negatively associated with pain-related quality of life after endometriosis surgery. Depression and musculoskeletal/myofascial pain (abdominal wall pain and pelvic floor myalgia) were the most important factors. Therefore, these pelvic pain comorbidities should be considered in a formal prediction model for pain outcomes after endometriosis surgery.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Mohamed A. Bedaiwy, Bahi Fayek, Emily C. Yang, Mahmoud S. Iews, Mohamed Elgendi, Amr O. Abdelkareem, Ahmed H. Abdellah, Yang Doris Liu, Adrian Jones, Ulrike Mayer, Faten F. Abdel Hafez
Summary: This study examined the impact of non-visualized pregnancy loss (NVPL) on future reproductive outcomes in patients with recurrent pregnancy loss (RPL). The results showed that the number of previous NVPLs is a significant predictor of subsequent live birth.
HUMAN REPRODUCTION
(2023)
Letter
Public, Environmental & Occupational Health
Sarka Lisonkova, Jeffrey N. N. Bone, Giulia M. M. Muraca, Neda Razaz, Amelie Boutin, Justin S. S. Brandt, Mohamed A. A. Bedaiwy, Cande V. V. Ananth, K. S. Joseph
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)
Article
Obstetrics & Gynecology
Ann Korkidakis, Arianne Y. Albert, Irene Jiang, Jefferson Terry, Faten F. AbdelHafez, Mohamed A. Bedaiwy
Summary: The study aimed to investigate the relationship between embryonic chromosomal errors in products of conception (POC) and maternal age, gestational age (GA) of pregnancy loss, and findings on routine recurrent pregnancy loss (RPL) workup. A retrospective cohort study of women with a history of >= 2 pregnancy losses was conducted, analyzing 1107 miscarriages from 741 women who underwent cytogenetic testing. The results showed a linear relationship between embryonic chromosomal errors and maternal age, as well as GA of pregnancy loss. Women with positive findings on routine RPL workup had lower odds of chromosomal errors. The study suggests that primary cytogenetic testing on POCs should be offered to all RPL patients.
REPRODUCTIVE SCIENCES
(2023)
Article
Medicine, General & Internal
Natasha L. Orr, Alice J. Huang, Yang Doris Liu, Heather Noga, Mohamed A. Bedaiwy, Christina Williams, Catherine Allaire, Paul J. Yong
Summary: This study aimed to examine the association between baseline Central Sensitization Inventory scores and postsurgical pain outcomes in patients with endometriosis. The results showed that higher Central Sensitization Inventory scores were significantly associated with worse chronic pelvic pain, deep dyspareunia, dyschezia, and back pain at follow-up.
Article
Obstetrics & Gynecology
Brittany MacGregor, Catherine Allaire, Mohamed A. Bedaiwy, Paul J. Yong, Olga Bougie
Summary: Dysmenorrhea is a common gynecologic condition with significant impact on quality of life. It can lead to chronic pelvic pain if left untreated. Treatment should be tailored to individual symptoms.
INTERNATIONAL JOURNAL OF WOMENS HEALTH
(2023)
Article
Health Care Sciences & Services
Sandy X. J. Zhang, Rebecca G. K. MacLeod, Gurkiran Parmar, Natasha L. Orr, Kate J. Wahl, Heather Noga, Arianne Albert, Ryan Flannigan, Lori A. Brotto, Paul J. Yong
Summary: This study aims to assess the acceptability of a phallus length reducer for reducing endometriosis-associated deep dyspareunia and the feasibility of a randomized controlled trial. The study will recruit 40 patients with diagnosed endometriosis and their sexual partners to assess deep dyspareunia severity using the reducer and self-assessment. The findings will provide preliminary evidence for the self-assessment and management of endometriosis-associated deep dyspareunia.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Obstetrics & Gynecology
Emily C. Yang, Nicole A. Koenig, Merry Gong, Lori A. Brotto, Alasdair M. Barr, Terry Lee, Paul J. Yong, Roxana Geoffrion
Summary: A cross-sectional study was conducted to investigate the patterns and willingness of cannabis product use among chronic pelvic pain patients. Most cannabis users found cannabis effective in relieving pelvic pain. Non-users showed interest in using cannabis for pain relief, with concerns about lack of information and potential adverse effects. Vaginal and vulvar application of cannabis products for pelvic pain showed strong interest among both users and non-users, suggesting the need for further research.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY-X
(2023)
Review
Urology & Nephrology
Agnes N. Mwaura, Nisha Marshall, Michael S. Anglesio, Paul J. Yong
Summary: Deep dyspareunia is a common cause of endometriosis, while provoked vestibulodynia is a common cause of superficial dyspareunia. The etiology of dyspareunia in both conditions is multifactorial and may include the role of neurogenesis or neuroproliferation that sensitizes pelvic structures and leads to pain with contact.
SEXUAL MEDICINE REVIEWS
(2023)
Article
Urology & Nephrology
Rebecca G. K. MacLeod, Gurkiran Parmar, Sandy Zhang, Heather Noga, Catherine Allaire, Arianne Albert, Ryan Flannigan, Lori A. Brotto, Natasha L. Orr, Kate Wahl, Paul J. Yong
Summary: This study assessed the acceptability, test-retest reliability, and validity of a vaginal insert for self-assessment of endometriosis-associated deep dyspareunia. The results showed that the vaginal insert was acceptable and reliable for self-assessment of deep dyspareunia, with initial evidence of validity.
JOURNAL OF SEXUAL MEDICINE
(2023)
Article
Medicine, General & Internal
Thomas Bouchard, Paul Yong, Patricia Doyle-Baker
Summary: The Quantum Menstrual Health Monitoring Study aims to characterize patterns of ovulation by measuring key reproductive hormones in urine and compare them to serum hormones and ultrasound results. It will recruit three groups to study regular cycles, irregular cycles in individuals with polycystic ovarian syndrome, and irregular cycles in individuals participating in high levels of exercise. The study results may have implications for menstrual health and fertility decision-making.
MEDICINA-LITHUANIA
(2023)
