4.2 Article

Cerebral embolic protection systems for transcatheter aortic valve replacement

Journal

JOURNAL OF INTERVENTIONAL CARDIOLOGY
Volume 31, Issue 6, Pages 891-898

Publisher

WILEY
DOI: 10.1111/joic.12573

Keywords

cerebral embolic protection; cerebral protection devices; stroke; TAVI; TAVR

Ask authors/readers for more resources

In the recent years, ischemic brain injury related to embolization after transcatheter aortic valve replacement (TAVR) has received increased attention as new embolic protection strategies emerged to protect the brain. Diverse cerebral protection devices have been developed to reduce cerebral embolization during TAVR. These devices work through various mechanisms and are in different stages of clinical translation. This review provides the evidence-based review of peri-procedural stroke prevention during TAVR and summarizes currently available cerebral embolic protection devices.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Cardiac & Cardiovascular Systems

Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart)

Suleman Aktaa, Gorav Batra, Stefan K. James, Daniel J. Blackman, Peter F. Ludman, Mamas A. Mamas, Mohamed Abdel-Wahab, Gianni D. Angelini, Martin Czerny, Victoria Delgado, Giuseppe De Luca, Agricola Eustachio, Dan Foldager, Christian W. Hamm, Bernard Iung, Norman Mangner, Julinda Mehilli, Gavin J. Murphy, Darren Mylotte, Radoslaw Parma, Anna Sonia Petronio, Bodgan A. Popescu, Lars Sondergaard, Rui C. Teles, Manel Sabate, Christian J. Terkelsen, Luca Testa, Jianhua Wu, Aldo P. Maggioni, Lars Wallentin, Barbara Casadei, Chris P. Gale

Summary: The EuroHeart project aims to create pan-European data standards for cardiovascular diseases and interventions, including TAVI, to quantify quality of care and patient outcomes.

EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES (2023)

Article Immunology

Incidence, Clinical Characteristics, and Impact of Absent Echocardiographic Signs in Patients With Infective Endocarditis After Transcatheter Aortic Valve Implantation

Norman Mangner, Vassili Panagides, David del Val, Mohamed Abdel-Wahab, Lisa Crusius, Eric Durand, Nikolaj Ihlemann, Marina Urena, Costanza Pellegrini, Francesco Giannini, Tomasz Gasior, Wojtek Wojakowski, Martin Landt, Vincent Auffret, Jan-Malte Sinning, Asim N. Cheema, Luis Nombela-Franco, Chekrallah Chamandi, Francisco Campelo-Parada, Erika Munoz-Garcia, Howard C. Herrmann, Luca Testa, Won-Keun Kim, Helene Eltchaninoff, Lars Sondergaard, Dominique Himbert, Oliver Husser, Azeem Latib, Herve Le Breton, Clement Servoz, Philippe Gervais, Melanie Cote, Holger Thiele, David Holzhey, Axel Linke, Josep Rodes-Cabau

Summary: In transcatheter aortic valve related infective endocarditis (IE), absent echocardiographic signs of IE were associated with the same prognosis as evident echocardiographic signs, highlighting the need for early treatment initiation in high-risk patients presenting with positive blood cultures and symptoms of infection after TAVI.

CLINICAL INFECTIOUS DISEASES (2023)

Article Cardiac & Cardiovascular Systems

Timing of Active Left Ventricular Unloading in Patients on Venoarterial Extracorporeal Membrane Oxygenation Therapy

Benedikt Schrage, Jonas Sundermeyer, Stefan Blankenberg, Pascal Colson, Dennis Eckner, Matthias Eden, Ingo Eitel, Derk Frank, Norbert Frey, Tobias Graf, Paulus Kirchhof, Danny Kupka, Ulf Landmesser, Axel Linke, Nicolas Majunke, Norman Mangner, Octavian Maniuc, Johannes Mierke, Sven Moebius-Winkler, David A. Morrow, Marc Mourad, Peter Nordbeck, Martin Orban, Federico Pappalardo, Sandeep M. Patel, Matthias Pauschinger, Vittorio Pazzanese, Darko Radakovic, P. Christian Schulze, Clemens Scherer, Robert H. G. Schwinger, Carsten Skurk, Holger Thiele, Anubodh Varshney, Lukas Wechsler, Dirk Westermann

Summary: This study evaluates the association between timing of active left ventricular (LV) unloading and implantation of VA-ECMO with outcomes in patients with cardiogenic shock (CS). The results show that early active LV unloading is associated with a lower risk of 30-day mortality and a higher likelihood of successful weaning from ventilation, without increasing complications.

JACC-HEART FAILURE (2023)

Article Cardiac & Cardiovascular Systems

Use of mechanical circulatory support in patients with non-ischaemic cardiogenic shock

Benedikt Schrage, Jonas Sundermeyer, Benedikt Norbert Beer, Letizia Bertoldi, Alexander Bernhardt, Stefan Blankenberg, Jeroen Dauw, Zouhir Dindane, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Peter Luedike, Enzo Luesebrink, Norman Mangner, Octavian Maniuc, Sven Moebius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, Paul Christian Schulze, Robert H. G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Antonia Wechsler, Ralf Westenfeld, Ephraim Winzer, Dirk Westermann

Summary: This study aimed to evaluate the use of mechanical circulatory support (MCS) for the treatment of non-ischaemic cardiogenic shock (CS). The results showed that the use of MCS was associated with a lower 30-day mortality rate in patients with non-ischaemic CS. However, MCS treatment was also associated with more complications.

EUROPEAN JOURNAL OF HEART FAILURE (2023)

Article Medicine, General & Internal

Impact of Enterococci vs. Staphylococci Induced Infective Endocarditis after Transcatheter Aortic Valve Implantation

Tomasz Gasior, Felix J. Woitek, Antonia Schroth, Mohamed Abdel-Wahab, Lisa Crusius, Stephan Haussig, Philipp Kiefer, Piotr Scislo, Zenon Huczek, Maciej Dabrowski, Adam Witkowski, Anna Olasinska-Wisniewska, Marek Grygier, Marcin Protasiewicz, Damian Hudziak, Utz Kappert, David Holzhey, Wojtek Wojakowski, Axel Linke, Norman Mangner

Summary: This study compared the clinical characteristics and outcomes of patients with enterococci infective endocarditis (EC-IE) and staphylococci infective endocarditis (SC-IE) following transcatheter aortic valve implantation. The results showed that EC-IE was associated with lower morbidity and mortality compared to SC-IE.

JOURNAL OF CLINICAL MEDICINE (2023)

Article Medicine, General & Internal

Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction

B. E. Stahli, F. Varbella, A. Linke, B. Schwarz, S. B. Felix, M. Seiffert, R. Kesterke, P. Nordbeck, B. Witzenbichler, I. M. Lang, M. Kessler, C. Valina, A. Dibra, M. Rohla, M. Moccetti, M. Vercellino, L. Gaede, L. Bott-Flugel, P. Jakob, J. Stehli, A. Candreva, C. Templin, M. Schindler, M. Wischnewsky, G. Zanda, G. Quadri, N. Mangner, A. Toma, G. Magnani, P. Clemmensen, T. F. Luscher, T. Munzel, P. C. Schulze, K. -L. Laugwitz, W. Rottbauer, K. Huber, F. -J. Neumann, S. Schneider, F. Weidinger, S. Achenbach, G. Richardt, A. Kastrati, I. Ford, W. Maier, F. Ruschitzka

Summary: This study investigated the timing of complete revascularization in patients with STEMI and multivessel coronary artery disease. The findings suggest that immediate multivessel PCI is as effective as staged PCI.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

Review Cardiac & Cardiovascular Systems

Locomotor and respiratory muscle abnormalities in HFrEF and HFpEF

Norman Mangner, Ephraim B. Winzer, Axel Linke, Volker Adams

Summary: This review provides a contemporary summary of the clinical and molecular alterations in the skeletal muscles of heart failure patients, with a focus on the effects on locomotor and respiratory muscles, particularly the diaphragm. It also discusses current and future therapeutic options, mainly focusing on the effects of exercise training.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2023)

Correction Cardiac & Cardiovascular Systems

Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) (October, qcac063, 2022)

Suleman Aktaa, Gorav Batra, Stefan K. James, Daniel J. Blackman, Peter F. Ludman, Mamas A. Mamas, Mohamed Abdel-Waha, Gianni D. Angelini, Martin Czerny, Victoria Delgado, Giuseppe De Luca, Eustachio Agricola, Dan Foldage, Christian W. Hamm, Bernard Iung, Norman Mangner, Julinda Mehilli, Gavin J. Murphy, Darren Mylotte, Radoslaw Parma, Anna Sonia Petronio, Bodgan A. Popescu, Lars Sondergaard, Rui C. Teles, Manel Sabate, Christian J. Terkelsen, Luca Testa, Jianhua Wu, Aldo P. Maggioni, Lars Wallentin, Barbara Casade, Chris P. Gale

EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES (2023)

Article Cardiac & Cardiovascular Systems

VARC-3 defined outcome of valve-in-valve transcatheter aortic valve implantation in stentless compared with stented aortic bioprostheses

Jean-Honore Steul, Mohamed Abdel-Wahab, Tomasz Stankowski, Stephan Haussig, Felix J. Woitek, Tomasz Gasior, Lisa Crusius, Luise Knorr, Felicitas V. Mueller, Dirk Fritzsche, Philipp Kiefer, Utz Kappert, David Holzhey, Axel Linke, Norman Mangner

Summary: This study compared the outcomes of ViV-TAVI in patients with stentless and stented aortic bioprosthetic valve failure. The study found that both groups had comparable technical success, device success, and early safety. There were no significant differences in 30-day and 5-year mortality rates between the two groups.

CLINICAL RESEARCH IN CARDIOLOGY (2023)

Meeting Abstract Cardiac & Cardiovascular Systems

Clinical presentation, shock severity and mortality in patients with de novo vs. acute-on-chronic heart failure-related cardiogenic shock

J. Jonas Sundermeyer, F. Gustafsson, C. Kellner, B. N. Beer, S. Blankenberg, P. Kirchhof, P. Luedike, N. Mangner, P. Nordbeck, M. Orban, A. Proudfoot, G. Tavazzi, H. Thiele, D. Westermann, B. Schrage

EUROPEAN JOURNAL OF HEART FAILURE (2023)

Article Cardiac & Cardiovascular Systems

Accelerometer vs. other activity measures in heart failure with preserved ejection fraction: the VITALITY-HFpEF trial

Javed Butler, Muhammad Shahzeb Khan, Tomasz Gasior, Tyler R. Erickson, Vanja Vlajnic, Frank Kramer, Robert O. Blaustein, David Goldsbury, Lothar Roessig, Carolyn S. P. Lam, Kevin J. Anstrom, Paul W. Armstrong

Summary: This study found that accelerometer-based activity measures did not correlate with subjective or objective standard measures of health status and functional capacity in heart failure with preserved ejection fraction.

ESC HEART FAILURE (2023)

Article Cardiac & Cardiovascular Systems

Continued non-vitamin K antagonist oral anticoagulants versus vitamin K antagonists during transcatheter aortic valve implantation

Norman Mangner, Miriam Brinkert, Lukas S. Keller, Noriaki Moriyama, Daniel Hagemeyer, Stephan Haussig, Lisa Crusius, Richard Kobza, Mohamed Abdel-Wahab, Mika Laine, Stefan Stortecky, Thomas Pilgrim, Fabian Nietlispach, Frank Ruschitzka, Holger Thiele, Stefan Toggweiler, Axel Linke

Summary: This study aimed to investigate the safety and effectiveness of continued non-vitamin K antagonist oral anticoagulant (NOAC) therapy compared with continued vitamin K antagonist (VKA) therapy during transcatheter aortic valve implantation (TAVI). The study found that continued NOAC therapy led to comparable outcomes to continued VKA therapy, suggesting that both drugs can be used for long-term oral anticoagulation in TAVI patients.

EUROINTERVENTION (2023)

Article Cardiac & Cardiovascular Systems

Procedural and one-year outcomes of the BASILICA technique in Europe: the multicentre EURO-BASILICA registry

Mohamed Abdel-Wahab, Ines Richter, Maurizio Taramasso, Axel Unbehaun, Tanja K. Rudolph, Flavio Ribichini, Ronald Binder, Joachim Schofer, Norman Mangner, Jan-Henk Dambrink, Blanca Trejo-Velasco, Holger Thiele, Mitsunobu Kitamura, Jonas Lanz

Summary: This study evaluated the procedural and one-year outcomes of the BASILICA technique in high-risk patients undergoing TAVI. The results showed that BASILICA was feasible and effective in preventing TAVI-induced CAO, and the one-year clinical outcomes were favorable.

EUROINTERVENTION (2023)

No Data Available