Distinct Roles for CD4+ Foxp3+ Regulatory T Cells and IL-10–Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by Leishmania donovani

HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis

(2017) Akil Hammami et al.   PLoS Pathogens

The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria

(2016) Marcela Montes de Oca et al.   JOURNAL OF IMMUNOLOGY

IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo

(2016) Leonie Brockmann et al.   JOURNAL OF IMMUNOLOGY

Elimination of visceral leishmaniasis on the Indian subcontinent

(2016) Om Prakash Singh et al.   LANCET INFECTIOUS DISEASES

Expanding antigen-specific regulatory networks to treat autoimmunity

(2016) Xavier Clemente-Casares et al.   NATURE

Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection

(2016) Marcela Montes de Oca et al.   Cell Reports

Induction of IL-10 and TGFβ from CD4+CD25+FoxP3+ T Cells Correlates with Parasite Load in Indian Kala-azar Patients Infected with Leishmania donovani

(2016) Pradyot Bhattacharya et al.   PLoS Neglected Tropical Diseases

Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology

(2016) Marcela Montes de Oca et al.   PLoS Pathogens

Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4 + T cells

(2015) Zhirong Mou et al.   Science Translational Medicine

CD4+ T Cells: Guardians of the Phagosome

(2014) N. J. Tubo et al.   CLINICAL MICROBIOLOGY REVIEWS

Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity

(2014) Ashraful Haque et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Tissue Requirements for Establishing Long-Term CD4+ T Cell-Mediated Immunity following Leishmania donovani Infection

(2014) P. T. Bunn et al.   JOURNAL OF IMMUNOLOGY

Exposure-Dependent Control of Malaria-Induced Inflammation in Children

(2014) Silvia Portugal et al.   PLoS Pathogens

IFNγ/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria in Highly Exposed Children

(2014) Prasanna Jagannathan et al.   PLoS Pathogens

The Regulation of CD4+ T Cell Responses during Protozoan Infections

(2014) Christian R. Engwerda et al.   Frontiers in Immunology

Common variants in the HLA-DRB1–HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

(2013) Michaela Fakiola et al.   NATURE GENETICS

Marginal Zone B Cells Regulate Antigen-Specific T Cell Responses during Infection

(2012) R. Bankoti et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Suppress T Cell Activation at the Pathologic Site of Human Visceral Leishmaniasis

(2012) Ambak K. Rai et al.   PLoS One

Involvement of CD4+ Foxp3+ Regulatory T Cells in Persistence of Leishmania donovani in the Liver of Alymphoplastic aly/aly Mice

(2012) Saruda Tiwananthagorn et al.   PLoS Neglected Tropical Diseases

IL-10-Producing Th1 Cells and Disease Progression Are Regulated by Distinct CD11c+ Cell Populations during Visceral Leishmaniasis

(2012) Benjamin M. J. Owens et al.   PLoS Pathogens

IL-10 Limits Parasite Burden and Protects against Fatal Myocarditis in a Mouse Model of Trypanosoma cruzi Infection

(2011) E. Roffe et al.   JOURNAL OF IMMUNOLOGY

IL-27 Promotes IL-10 Production by Effector Th1 CD4+ T Cells: A Critical Mechanism for Protection from Severe Immunopathology during Malaria Infection

(2011) A. P. Freitas do Rosario et al.   JOURNAL OF IMMUNOLOGY

IL-10 Neutralization Promotes Parasite Clearance in Splenic Aspirate Cells From Patients With Visceral Leishmaniasis

(2011) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor

(2011) E. Narni-Mancinelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation

(2010) Eszter Deak et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+ Natural Regulatory T Cells Prevent Experimental Cerebral Malaria via CTLA-4 When Expanded In Vivo

(2010) Ashraful Haque et al.   PLoS Pathogens

Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model

(2009) Marina C. Pils et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by Bacteria Promotes Regulatory Properties of Neutrophils

(2009) Xiaoming Zhang et al.   IMMUNITY

Regulatory B Cells Shape the Development of Th2 Immune Responses in BALB/c Mice Infected with Leishmania major Through IL-10 Production

(2009) C. Ronet et al.   JOURNAL OF IMMUNOLOGY

From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce TH1 development

(2009) Anne O'Garra et al.   NATURE IMMUNOLOGY

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

(2009) D. Ranatunga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Roles for FOXP3+ and FOXP3− CD4+ T Cells in Regulating Cellular Immunity to Uncomplicated and Severe Plasmodium falciparum Malaria

(2009) Michael Walther et al.   PLoS Pathogens

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Posttranscriptional Regulation of Il10 Gene Expression Allows Natural Killer Cells to Express Immunoregulatory Function

(2008) Asher Maroof et al.   IMMUNITY

IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection

(2008) Kevin N. Couper et al.   PLoS Pathogens

VCAM-1 and VLA-4 Modulate Dendritic Cell IL-12p40 Production in Experimental Visceral Leishmaniasis

(2008) Amanda C. Stanley et al.   PLoS Pathogens

Activation of Invariant NKT Cells Exacerbates Experimental Visceral Leishmaniasis

(2008) Amanda C. Stanley et al.   PLoS Pathogens