DHHC protein family targets different subsets of glioma stem cells in specific niches

Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors

(2018) Marat S. Pavlyukov et al.   CANCER CELL

Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells

(2018) Jianghong Man et al.   Cell Stem Cell

Primary brain tumours in adults

(2018) Sarah Lapointe et al.   LANCET

Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas

(2017) C. J. Herting et al.   GLIA

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2

(2017) Jia Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Palmitoylation-dependent activation of MC1R prevents melanomagenesis

(2017) Shuyang Chen et al.   NATURE

Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia

(2017) D A Almiron Bonnin et al.   ONCOGENE

Immunotherapies for malignant glioma

(2017) Vassiliki A. Boussiotis et al.   ONCOGENE

MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer

(2017) Jakub Godlewski et al.   Stem Cell Reports

Melatonin inhibits tumorigenicity of glioblastoma stem-like cells via the AKT-EZH2-STAT3 signaling axis

(2016) Xueran Chen et al.   JOURNAL OF PINEAL RESEARCH

Downregulation of solute carriers of glutamate in gliosomes and synaptosomes may explain local brain metastasis in anaplastic glioblastoma

(2015) Huaiyu Tong et al.   IUBMB LIFE

IDH1R132H decreases the proliferation of U87 glioma cells through upregulation of microRNA-128a

(2015) QUAN-MIN NIE et al.   Molecular Medicine Reports

Unravelling tumour heterogeneity—implications for therapy

(2015) David A. Reardon et al.   Nature Reviews Clinical Oncology

The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeutics

(2015) J G Perez et al.   ONCOGENE

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity

(2014) M.-E. Bordeleau et al.   BLOOD

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch

(2014) E. Lopez-Arribillaga et al.   DEVELOPMENT

Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway

(2014) Guang-Ning Yan et al.   JOURNAL OF PATHOLOGY

New links betweenS-acylation and cancer

(2014) Jennifer Greaves et al.   JOURNAL OF PATHOLOGY

Hypoxia-induced Bmi1 promotes renal tubular epithelial cell–mesenchymal transition and renal fibrosis via PI3K/Akt signal

(2014) Rui Du et al.   MOLECULAR BIOLOGY OF THE CELL

RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage

(2014) Shiuh-Rong Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A glioma classification scheme based on coexpression modules of EGFR and PDGFRA

(2014) Yingyu Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Polycomb protein, Bmi1, regulates insulin sensitivity

(2014) Corey E. Cannon et al.   Molecular Metabolism

Mechanism and function of DHHC S-acyltransferases: Figure 1

(2013) Maurine E. Linder et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

(2013) Gaetano Gargiulo et al.   CANCER CELL

MicroRNA-218 Inhibits Glioma Invasion, Migration, Proliferation, and Cancer Stem-like Cell Self-Renewal by Targeting the Polycomb Group Gene Bmi1

(2013) Y. Tu et al.   CANCER RESEARCH

Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition

(2013) Y. Piao et al.   CLINICAL CANCER RESEARCH

Reduced Expression of ZDHHC2 Is Associated with Lymph Node Metastasis and Poor Prognosis in Gastric Adenocarcinoma

(2013) Shu-Mei Yan et al.   PLoS One

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells

(2013) Branavan Manoranjan et al.   STEM CELLS

A High Notch Pathway Activation Predicts Response to γ Secretase Inhibitors in Proneural Subtype of Glioma Tumor-Initiating Cells

(2013) Norihiko Saito et al.   STEM CELLS

The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation

(2013) Danila Coradini et al.   Chinese Journal of Cancer

Medulloblastoma stem cells: Modeling tumor heterogeneity

(2012) Branavan Manoranjan et al.   CANCER LETTERS

Epigenetic inheritance of cell differentiation status

(2011) Ray K. Ng et al.   CELL CYCLE

Molecular subclassification of diffuse gliomas: Seeing order in the chaos

(2011) Jason T. Huse et al.   GLIA

Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells

(2011) X Wang et al.   ONCOGENE

Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells

(2011) Chitra Venugopal et al.   Stem Cell Research

The Use of Global Profiling in Biomarker Development for Gliomas

(2010) Erik P. Sulman et al.   BRAIN PATHOLOGY

Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer

(2008) Ji Un Kang et al.   CANCER GENETICS AND CYTOGENETICS

Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs

(2008) Mikko Gynther et al.   JOURNAL OF MEDICINAL CHEMISTRY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE