Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

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Intratumoral CD8 + T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

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L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

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Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer

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Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

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Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

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CD137 Accurately Identifies and Enriches for Naturally Occurring Tumor-Reactive T Cells in Tumor

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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

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The Tumor Microenvironment and Strategies to Improve Drug Distribution

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Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

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SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

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Combination CTLA-4 Blockade and 4-1BB Activation Enhances Tumor Rejection by Increasing T-Cell Infiltration, Proliferation, and Cytokine Production

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Tumor Vaccines Expressing Flt3 Ligand Synergize with CTLA-4 Blockade to Reject Preimplanted Tumors

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Divergent Effects of Castration on Prostate Cancer in TRAMP Mice: Possible Implications for Therapy

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Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α

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Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs

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Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer

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