CX3CR1-CCR2-dependent monocyte-microglial signaling modulates neurovascular leakage and acute injury in a mouse model of childhood stroke

Recent advances in the understanding of microglial development and homeostasis

(2018) Donovan Low et al.   CELLULAR IMMUNOLOGY

Endogenous protection from ischemic brain injury by preconditioned monocytes

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Microglia and Neonatal Brain Injury

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A new fate mapping system reveals context-dependent random or clonal expansion of microglia

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Vascular impairment as a pathological mechanism underlying long-lasting cognitive dysfunction after pediatric traumatic brain injury

(2017) Aleksandra Ichkova et al.   NEUROCHEMISTRY INTERNATIONAL

Traumatic brain injury results in acute rarefication of the vascular network

(2017) Andre Obenaus et al.   Scientific Reports

Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation

(2016) Francesc Miró-Mur et al.   BRAIN BEHAVIOR AND IMMUNITY

Executive Summary: Heart Disease and Stroke Statistics—2016 Update

(2016) Dariush Mozaffarian et al.   CIRCULATION

Susceptibility-Weighted Imaging Identifies Iron-Oxide-Labeled Human Neural Stem Cells: Automated Computational Detection

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Dark microglia: A new phenotype predominantly associated with pathological states

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Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain

(2016) Lidia Garcia-Bonilla et al.   Journal of Neuroinflammation

Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke

(2016) D. Fernandez-Lopez et al.   JOURNAL OF NEUROSCIENCE

Enriched dairy fat matrix diet prevents early life lipopolysaccharide-induced spatial memory impairment at adulthood

(2016) A.L. Dinel et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis?

(2016) Felix Wei et al.   STROKE

Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke

(2016) Heather J. Fullerton et al.   STROKE

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

(2016) Gergely Szalay et al.   Nature Communications

A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+monocytes at a site of sterile injury

(2015) Daniela Dal-Secco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lack of the scavenger receptor CD36 alters microglial phenotypes after neonatal stroke

(2015) Fan Li et al.   JOURNAL OF NEUROCHEMISTRY

Paediatric stroke: pressing issues and promising directions

(2015) Adam Kirton et al.   LANCET NEUROLOGY

The role of inflammation in perinatal brain injury

(2015) Henrik Hagberg et al.   Nature Reviews Neurology

Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain

(2015) Bridgette D. Semple et al.   NEUROBIOLOGY OF DISEASE

Caveolin expression changes in the neurovascular unit after juvenile traumatic brain injury: Signs of blood–brain barrier healing?

(2015) J. Badaut et al.   NEUROSCIENCE

Juvenile Traumatic Brain Injury Induces Long-Term Perivascular Matrix Changes Alongside Amyloid-Beta Accumulation

(2014) Amandine Jullienne et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanisms of Perinatal Arterial Ischemic Stroke

(2014) David Fernández-López et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CCR2+Ly6Chi Inflammatory Monocyte Recruitment Exacerbates Acute Disability Following Intracerebral Hemorrhage

(2014) M. D. Hammond et al.   JOURNAL OF NEUROSCIENCE

Automated detection of brain abnormalities in neonatal hypoxia ischemic injury from MR images

(2014) Nirmalya Ghosh et al.   MEDICAL IMAGE ANALYSIS

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Microglia Modulate Wiring of the Embryonic Forebrain

(2014) Paola Squarzoni et al.   Cell Reports

Gestational Exposure to a Viral Mimetic Poly(I:C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring

(2013) Cecilia Giulivi et al.   MEDIATORS OF INFLAMMATION

Layer V cortical neurons require microglial support for survival during postnatal development

(2013) Masaki Ueno et al.   NATURE NEUROSCIENCE

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

Macrophages prevent hemorrhagic infarct transformation in murine stroke models

(2012) Michael Gliem et al.   ANNALS OF NEUROLOGY

Genetic deletion of CD36 enhances injury after acute neonatal stroke

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Blood-Brain Barrier Permeability Is Increased After Acute Adult Stroke But Not Neonatal Stroke in the Rat

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Deficiency of the Microglial Receptor CX3CR1 Impairs Postnatal Functional Development of Thalamocortical Synapses in the Barrel Cortex

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The Vascular Effects of Infection in Pediatric Stroke (VIPS) Study

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Automated ischemic lesion detection in a neonatal model of hypoxic ischemic injury

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The immunology of stroke: from mechanisms to translation

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Symptomatic Neonatal Arterial Ischemic Stroke: The International Pediatric Stroke Study

(2011) A. Kirton et al.   PEDIATRICS

A Computational Tool for Quantitative Analysis of Vascular Networks

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Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

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Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

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Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

Pediatric stroke: the importance of cerebral arteriopathy and vascular malformations

(2010) Lauren A. Beslow et al.   CHILDS NERVOUS SYSTEM

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

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Predictors of Cerebral Arteriopathy in Children With Arterial Ischemic Stroke

(2009) Catherine Amlie-Lefond et al.   CIRCULATION

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

(2009) Yoshiaki Kubota et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

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Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

The varicella zoster virus vasculopathies: Clinical, CSF, imaging, and virologic features

(2008) M. A. Nagel et al.   NEUROLOGY