Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3

Long pentraxin 3: A novel multifaceted player in cancer

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Oleate-induced PTX3 promotes head and neck squamous cell carcinoma metastasis through the up-regulation of vimentin

(2017) Shih-Hung Chan et al.   Oncotarget

Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-κB/STAT3 signaling cascade

(2016) Zhengle Zhang et al.   CANCER LETTERS

Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways

(2016) Lei Cao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling

(2016) Barbara Bottazzi et al.   JOURNAL OF HEPATOLOGY

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling

(2016) Claudia Cappuzzello et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Inhibition of pentraxin 3 in glioma cells impairs proliferation and invasion in vitro and in vivo

(2016) Jai-Nien Tung et al.   JOURNAL OF NEURO-ONCOLOGY

Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells

(2016) Tsung-Ho Ying et al.   Scientific Reports

Gemcitabine-induced CXCL8 expression counteracts its actions by inducing tumor neovascularization

(2015) Yao Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

(2015) Roberto Ronca et al.   CANCER CELL

PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

(2015) Eduardo Bonavita et al.   CELL

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

(2015) Maurizio Infante et al.   INTERNATIONAL JOURNAL OF CANCER

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death

(2015) XIU SHAN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Pentraxin 3 as a clinical marker in children with lower respiratory tract infection

(2015) Hwan Soo Kim et al.   PEDIATRIC PULMONOLOGY

PTX3 gene activation in EGF-induced head and neck cancer cell metastasis

(2015) Wei-Chiao Chang et al.   Oncotarget

Curcumin Inhibits Non-Small Cell Lung Cancer Cells Metastasis through the Adiponectin/NF-κb/MMPs Signaling Pathway

(2015) Jong-Rung Tsai et al.   PLoS One

Clinical impact of pentraxin family expression on prognosis of pancreatic carcinoma

(2013) S Kondo et al.   BRITISH JOURNAL OF CANCER

An Undesired Effect of Chemotherapy

(2013) Sumit Arora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB

(2012) Ajay P. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pentraxin-3 Is a Novel Biomarker of Lung Carcinoma

(2011) E. P. Diamandis et al.   CLINICAL CANCER RESEARCH

Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment

(2010) Marco Tafani et al.   CANCER SCIENCE

Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-κB

(2010) Sun Mi Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Clinical pharmacology and pharmacogenetics of gemcitabine

(2009) Andrea Wong et al.   DRUG METABOLISM REVIEWS

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Nuclear factor-κB dependency of doxorubicin sensitivity in gastric cancer cells is determined by manganese superoxide dismutase expression

(2008) Sung Jin Cho et al.   CANCER SCIENCE

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

(2008) Seung-Nam Jung et al.   CARCINOGENESIS

Efficacy of Gemcitabine in Patients with Non-Small Cell Lung Cancer According to Promoter Polymorphisms of the Ribonucleotide Reductase M1 Gene

(2008) S.-O. Kim et al.   CLINICAL CANCER RESEARCH

Chemoresistant tumor cell lines display altered epidermal growth factor receptor and HER3 signaling and enhanced sensitivity to gefitinib

(2008) Tiziana Servidei et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE