Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2-like 2 (NFE2L2) protein and the Smad2/3 pathway

The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease

(2016) Natalie Jumper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keloids: The paradigm of skin fibrosis — Pathomechanisms and treatment

(2016) Jonathan P. Andrews et al.   MATRIX BIOLOGY

Nrf2-dependent protection against acute sodium arsenite toxicity in zebrafish

(2016) Yuji Fuse et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Accumulation of isolevuglandin-modified protein in normal and fibrotic lung

(2016) Stacey Mont et al.   Scientific Reports

2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells

(2015) Xuezhong Gong et al.   ARCHIVES OF TOXICOLOGY

Arsenic Trioxide Activate Transcription of Heme Oxygenase-1 by Promoting Nuclear Translocation of NFE2L2

(2015) Zhen Yue et al.   International Journal of Medical Sciences

Chemokine Involvement in Fetal and Adult Wound Healing

(2015) Swathi Balaji et al.   Advances in Wound Care

Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation

(2015) Hisako Ishise et al.   Scientific Reports

Involvement of Nrf2-GSH signaling in TGFβ1-stimulated epithelial-to-mesenchymal transition changes in rat renal tubular cells

(2014) In-geun Ryoo et al.   ARCHIVES OF PHARMACAL RESEARCH

Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway

(2014) Xuefen Xu et al.   BIOCHEMICAL PHARMACOLOGY

Nitrated fatty acids reverse pulmonary fibrosis by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages

(2014) Aravind T. Reddy et al.   FASEB JOURNAL

Heme oxygenase-1 silencing increases the sensitivity of human osteosarcoma MG63 cells to arsenic trioxide

(2014) Lingzhi Zhong et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo

(2014) Fayong Luo et al.   RESPIRATORY RESEARCH

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

(2014) L. Hecker et al.   Science Translational Medicine

Bleomycin-induced epithelial–mesenchymal transition in sclerotic skin of mice: Possible role of oxidative stress in the pathogenesis

(2014) Cheng-Fan Zhou et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nuclear Factor Erythroid 2-Related Factor 2 Nuclear Translocation Induces Myofibroblastic Dedifferentiation in Idiopathic Pulmonary Fibrosis

(2012) Elise Artaud-Macari et al.   ANTIOXIDANTS & REDOX SIGNALING

Arsenic trioxide — An old drug rediscovered

(2010) Ashkan Emadi et al.   BLOOD REVIEWS

Arsenic Induces Apoptosis of Human Umbilical Vein Endothelial Cells Through Mitochondrial Pathways

(2010) Yanfen Shi et al.   Cardiovascular Toxicology

Ski, a modulator of wound healing and scar formation in the rat skin and rabbit ear

(2010) Ping Li et al.   JOURNAL OF PATHOLOGY

Health Effects of Arsenic and Chromium in Drinking Water: Recent Human Findings

(2008) Allan H. Smith et al.   Annual Review of Public Health

Arsenic Trioxide, Arsenic Pentoxide, and Arsenic Iodide Inhibit Human Keratinocyte Proliferation through the Induction of Apoptosis

(2008) W.-P. Tse et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Basic fibroblast growth factor (bFGF) alleviates the scar of the rabbit ear model in wound healing

(2008) Ju Lin Xie et al.   WOUND REPAIR AND REGENERATION

Autocrine TGF-β signaling in the pathogenesis of systemic sclerosis

(2007) Hironobu Ihn   JOURNAL OF DERMATOLOGICAL SCIENCE