Vaccarin prevents titanium particle-induced osteolysis and inhibits RANKL-induced osteoclastogenesis by blocking NF-κB and MAPK signaling pathways

Vaccaria hypaphorine impairs RANKL-induced osteoclastogenesis by inhibition of ERK, p38, JNK and NF-κB pathway and prevents inflammatory bone loss in mice

(2018) Hongxi Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Monocrotaline Suppresses RANKL-Induced Osteoclastogenesis In Vitro and Prevents LPS-Induced Bone Loss In Vivo

(2018) Cheng-Ming Wei et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vaccarin protects human microvascular endothelial cells from apoptosis via attenuation of HDAC1 and oxidative stress

(2018) Xuexue Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Denosumab May Increase the Risk of Local Recurrence in Patients with Giant-Cell Tumor of Bone Treated with Curettage

(2018) Costantino Errani et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Emodin attenuates titanium particle-induced osteolysis and RANKL-mediated osteoclastogenesis through the suppression of IKK phosphorylation

(2018) Juehong Li et al.   MOLECULAR IMMUNOLOGY

Luteoloside prevents lipopolysaccharide-induced osteolysis and suppresses RANKL-induced osteoclastogenesis through attenuating RANKL signaling cascades

(2017) Fangming Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Artesunate inhibits RANKL-induced osteoclastogenesis and bone resorption in vitro and prevents LPS-induced bone loss in vivo

(2017) Cheng-Ming Wei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Kaempferide Prevents Titanium Particle Induced Osteolysis by Suppressing JNK Activation during Osteoclast Formation

(2017) Zixian Jiao et al.   Scientific Reports

Scutellarin inhibits RANKL-mediated osteoclastogenesis and titanium particle-induced osteolysis via suppression of NF-κB and MAPK signaling pathway

(2016) Shuai Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dihydroartemisinin, an Anti-Malaria Drug, Suppresses Estrogen Deficiency-Induced Osteoporosis, Osteoclast Formation, and RANKL-Induced Signaling Pathways

(2016) Lin Zhou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

What potential biologic treatments are available for osteolysis?

(2016) Edward M. Schwarz   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation

(2016) Qian Liu et al.   Scientific Reports

Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model

(2015) Hongguo Shao et al.   BIOMATERIALS

What Can We Learn From 20-year Followup Studies of Hip Replacement?

(2015) Christopher T. Martin et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Suppression of wear-particle-induced pro-inflammatory cytokine and chemokine production in macrophages via NF-κB decoy oligodeoxynucleotide: A preliminary report

(2014) Tzu-hua Lin et al.   Acta Biomaterialia

Denosumab and osteonecrosis of the jaws - the pharmacology, pathogenesis and a report of two cases

(2014) M O'Halloran et al.   AUSTRALIAN DENTAL JOURNAL

Activation of p38 MAPK-regulated Bcl-xL signaling increases survival against zoledronic acid-induced apoptosis in osteoclast precursors

(2014) Ta-Wei Tai et al.   BONE

Revision joint replacement, wear particles, and macrophage polarization

(2012) Allison J. Rao et al.   Acta Biomaterialia

Highly Crosslinked Polyethylene Does Not Reduce Aseptic Loosening in Cemented THA 10-year Findings of a Randomized Study

(2012) Per-Erik Johanson et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Oestrogen deficiency modulates particle-induced osteolysis

(2011) Christophe Nich et al.   ARTHRITIS RESEARCH & THERAPY

NF-κB modulators in osteolytic bone diseases

(2008) Jiake Xu et al.   CYTOKINE & GROWTH FACTOR REVIEWS