Molecular biomarkers in cardiac hypertrophy

Physiological and pathological cardiac hypertrophy

(2016) Ippei Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

(2016) Jingyuan Li et al.   Oncotarget

miR-96 inhibits cardiac hypertrophy by targeting growth factor receptor-bound 2

(2015) Y. Xia et al.   GENETICS AND MOLECULAR RESEARCH

Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer

(2015) Weijie Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin inhibits proliferation and proinflammatory cytokines of human keratinocytesin vitrovia mTOR-signaling pathway

(2015) Ying Liu et al.   PHARMACEUTICAL BIOLOGY

Association between miR-181b and PKG 1 in myocardial hypertrophy and its clinical implications

(2015) WEI ZHONG et al.   Experimental and Therapeutic Medicine

miR-185 Plays an Anti-Hypertrophic Role in the Heart via Multiple Targets in the Calcium-Signaling Pathways

(2015) Jin Ock Kim et al.   PLoS One

Cardiac CaM Kinase II Genes δ and γ Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy

(2014) Michael M. Kreusser et al.   CIRCULATION

MicroRNA Regulation and Cardiac Calcium Signaling

(2014) Masahide Harada et al.   CIRCULATION RESEARCH

Growth Differentiation Factor (GDF)-15 Blocks Norepinephrine-induced Myocardial Hypertrophy via a Novel Pathway Involving Inhibition of Epidermal Growth Factor Receptor Transactivation

(2014) Xin-ye Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-34a Modulates Angiotensin II-Induced Myocardial Hypertrophy by Direct Inhibition of ATG9A Expression and Autophagic Activity

(2014) Jionghua Huang et al.   PLoS One

ThemiR-19a/bfamily positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1

(2013) Dong Woo Song et al.   BIOCHEMICAL JOURNAL

Overload Induced Heat Shock Proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) Response in Insulin-Resistant Skeletal Muscle

(2013) Anjaiah Katta et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

MiR-30-Regulated Autophagy Mediates Angiotensin II-Induced Myocardial Hypertrophy

(2013) Wei Pan et al.   PLoS One

The CD44high Tumorigenic Subsets in Lung Cancer Biospecimens Are Enriched for Low miR-34a Expression

(2013) Saroj K. Basak et al.   PLoS One

GDF-15 for Prognostication of Cardiovascular and Cancer Morbidity and Mortality in Men

(2013) Lars Wallentin et al.   PLoS One

Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts

(2012) Rui Guo et al.   Autophagy

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Recent advances in vascular development

(2012) Courtney K. Domigan et al.   CURRENT OPINION IN HEMATOLOGY

miR-30 Family Members Negatively Regulate Osteoblast Differentiation

(2012) Tingting Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells

(2012) Y Yu et al.   LEUKEMIA

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

(2012) Carolina E. Hagberg et al.   NATURE

CaMKII determines mitochondrial stress responses in heart

(2012) Mei-ling A. Joiner et al.   NATURE

Differential Expression of MicroRNAs in Adipose Tissue after Long-Term High-Fat Diet-Induced Obesity in Mice

(2012) Dionysios V. Chartoumpekis et al.   PLoS One

Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells

(2012) Yuchen Liu et al.   PLoS One

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer

(2012) XIN MIN XU et al.   Oncology Letters

MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9

(2011) Jurong Yang et al.   AGE

Relation of Growth-Differentiation Factor 15 to Left Ventricular Remodeling in ST-Segment Elevation Myocardial Infarction

(2011) Alberto Dominguez-Rodriguez et al.   AMERICAN JOURNAL OF CARDIOLOGY

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma

(2011) Amanda Tivnan et al.   BMC CANCER

Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1–Smad signalling

(2011) Ling Yan et al.   CARDIOVASCULAR RESEARCH

Growth differentiation factor-15, a novel biomarker related with disease severity in patients with hypertrophic cardiomyopathy

(2011) Silvia Montoro-García et al.   European Journal of Internal Medicine

Cardiac Myocyte-specific Ablation of Follistatin-like 3 Attenuates Stress-induced Myocardial Hypertrophy

(2011) Masayuki Shimano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

De Teare a nuestros días: una odisea de cincuenta años en la miocardiopatía hipertrófica, un paradigma en la lógica del proceso de descubrimiento

(2011) William J. Mckenna et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Relations of growth-differentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects

(2011) Kai M. Eggers et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis

(2011) Laure-Emmanuelle Zaragosi et al.   GENOME BIOLOGY

Dynamic Changes in Lung MicroRNA Profiles During the Development of Pulmonary Hypertension due to Chronic Hypoxia and Monocrotaline

(2010) Paola Caruso et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Growth differentiation factor 15 in different stages of heart failure: potential screening implications

(2010) Fangfang Wang et al.   BIOMARKERS

MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology

(2010) Yasutoshi Yamada et al.   CANCER SCIENCE

Serial Measurement of Growth-Differentiation Factor-15 in Heart Failure

(2010) Inder S. Anand et al.   CIRCULATION

Identification of MicroRNAs Regulating Reprogramming FactorLIN28in Embryonic Stem Cells and Cancer Cells

(2010) Xiaomin Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas

(2010) J Lin et al.   LEUKEMIA

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metabolism and Vascular Fatty Acid Transport

(2010) Deborah M. Muoio   NEW ENGLAND JOURNAL OF MEDICINE

miR-29 and miR-30 regulate B-Myb expression during cellular senescence

(2010) I. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gender-Specific Reduction of Estrogen-Sensitive Small RNA, miR-30b, in Subjects With Schizophrenia

(2010) Nikolaos Mellios et al.   SCHIZOPHRENIA BULLETIN

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway

(2010) Jincheng Li et al.   PLoS Genetics

Cardiomyocyte autophagy is regulated by angiotensin II type 1 and type 2 receptors

(2009) Enzo R. Porrello et al.   Autophagy

Growth-Differentiation Factor-15 for Long-Term Risk Prediction in Patients Stabilized After an Episode of Non–ST-Segment–Elevation Acute Coronary Syndrome

(2009) Kai M. Eggers et al.   Circulation-Cardiovascular Genetics

The haplotype of the growth-differentiation factor 15 gene is associated with left ventricular hypertrophy in human essential hypertension

(2009) Xiaojian Wang et al.   CLINICAL SCIENCE

Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction

(2009) S. Q. Khan et al.   EUROPEAN HEART JOURNAL

Growth-differentiation factor-15 is an independent marker of cardiovascular dysfunction and disease in the elderly: results from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) Study

(2009) L. Lind et al.   EUROPEAN HEART JOURNAL

Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

(2009) Haiyun Ling et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice

(2009) Dazhi Xiong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

(2009) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The   isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

(2009) J. Backs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Biology and Pathology of Lymphangiogenesis

(2008) Terhi Karpanen et al.   Annual Review of Pathology-Mechanisms of Disease

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

(2008) Yasunori Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy

(2008) Terhi Karpanen et al.   CIRCULATION RESEARCH

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

(2008) Rudy F. Duisters et al.   CIRCULATION RESEARCH

Alterations in circulating activin A, GDF-15, TGF-β3 and MMP-2, -3, and -9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis

(2008) Johannes L. Bjørnstad et al.   EUROPEAN JOURNAL OF HEART FAILURE