Transgelin as a potential target in the reversibility of pulmonary arterial hypertension secondary to congenital heart disease

Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research

(2018) Steeve Provencher et al.   CIRCULATION RESEARCH

Uremia does not affect neointima formation in mice

(2017) Annemarie Aarup et al.   Scientific Reports

SM22α inhibits lamellipodium formation and migration via Ras-Arp2/3 signaling in synthetic VSMCs

(2016) Pin Lv et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

iRAGE as a novel carboxymethylated peptide that prevents advanced glycation end product-induced apoptosis and endoplasmic reticulum stress in vascular smooth muscle cells

(2016) Jean-Sébastien Maltais et al.   PHARMACOLOGICAL RESEARCH

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization

(2016) M Elsafadi et al.   Cell Death & Disease

Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function

(2015) Elie Simard et al.   PLoS One

Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

(2014) Shanshan Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertension

(2014) Ruifeng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries

(2014) Xue Peng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

(2013) Joshua K. Salabei et al.   BIOCHEMICAL JOURNAL

Critical Role for the Advanced Glycation End‐Products Receptor in Pulmonary Arterial Hypertension Etiology

(2013) Jolyane Meloche et al.   Journal of the American Heart Association

Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery

(2012) Sukrutha Chettimada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Transgelin is a marker of repopulating mesangial cells after injury and promotes their proliferation and migration

(2012) Christoph Daniel et al.   LABORATORY INVESTIGATION

Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

(2011) Roxane Paulin et al.   CIRCULATION

Activation of Endothelin-1 Receptor Signaling Pathways Is Associated With Neointima Formation, Neoangiogenesis and Irreversible Pulmonary Artery Hypertension in Patients With Congenital Heart Disease

(2011) HaiQiong Huang et al.   CIRCULATION JOURNAL

From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension

(2011) Roxane Paulin et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Blockade of the Ras–Extracellular Signal–Regulated Kinase 1/2 Pathway Is Involved in Smooth Muscle 22α–Mediated Suppression of Vascular Smooth Muscle Cell Proliferation and Neointima Hyperplasia

(2010) Li-Hua Dong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Up-Regulation of Two Actin-Associated Proteins Prompts Pulmonary Artery Smooth Muscle Cell Migration under Hypoxia

(2009) Ruifeng Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dehydroepiandrosterone Reverses Systemic Vascular Remodeling Through the Inhibition of the Akt/GSK3-β/NFAT Axis

(2009) Sébastien Bonnet et al.   CIRCULATION

SM22α inhibits cell proliferation and protects against anticancer drugs and γ-radiation in HepG2 cells: Involvement of metallothioneins

(2009) Tae Rim Kim et al.   FEBS LETTERS

Time-Dependent Phenotypic and Contractile Changes of Pulmonary Artery in Chronic Hypoxia–Induced Pulmonary Hypertension

(2009) Daigo Aoshima et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

FRNK Expression Promotes Smooth Muscle Cell Maturation During Vascular Development and After Vascular Injury

(2008) Rebecca L. Sayers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Assessment of operability of congenital cardiac shunts with increased pulmonary vascular resistance

(2008) Sangeetha Viswanathan et al.   CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

Transgelin is a direct target of TGF-β/Smad3-dependent epithelial cell migration in lung fibrosis

(2008) Haiying Yu et al.   FASEB JOURNAL

Treatment and survival in children with pulmonary arterial hypertension: the UK Pulmonary Hypertension Service for Children 2001-2006

(2008) S G Haworth et al.   HEART

Transgelin: An actin-binding protein and tumour suppressor

(2008) Stephen J. Assinder et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Evaluating operability in adults with congenital heart disease and the role of pretreatment with targeted pulmonary arterial hypertension therapy

(2008) Konstantinos Dimopoulos et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY