Inhibition of stearoyl CoA desaturase-1 activity suppresses tumour progression and improves prognosis in human bladder cancer

Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

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Cancer treatment and survivorship statistics, 2016

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Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?

(2015) D. G. Hardie   CLINICAL CANCER RESEARCH

Aberrant Lipid Metabolism in Anaplastic Thyroid Carcinoma Reveals Stearoyl CoA Desaturase 1 as a Novel Therapeutic Target

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Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

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Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors

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Bladder Cancer Stem Cells: Biological and Therapeutic Perspectives

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Positive feedback loop and synergistic effects between hypoxia-inducible factor-2α and stearoyl-CoA desaturase-1 promote tumorigenesis in clear cell renal cell carcinoma

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Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen

(2013) Uri Ben-David et al.   Cell Stem Cell

Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma

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Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

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FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth

(2012) X. Du et al.   CANCER RESEARCH

Decreasing stearoyl-CoA desaturase-1 expression inhibits β-catenin signaling in breast cancer cells

(2012) Daniel Mauvoisin et al.   CANCER SCIENCE

Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells

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Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy

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Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation

(2011) Seung-Jin Kim et al.   MOLECULES AND CELLS

The fatty acid desaturation index of blood lipids, as a biomarker of hepatic stearoyl-CoA desaturase expression, is a predictive factor of breast cancer risk

(2010) Véronique Chajès et al.   CURRENT OPINION IN LIPIDOLOGY

Abrogation of De novo Lipogenesis by Stearoyl-CoA Desaturase 1 Inhibition Interferes with Oncogenic Signaling and Blocks Prostate Cancer Progression in Mice

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mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

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Bladder Cancer Stem Cells

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Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors

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Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK

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Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

(2009) K. S. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA