Article
Chemistry, Applied
Keysson V. Fernandes, Elisa D. C. Cavalcanti, Eliane P. Cipolatti, Erika C. G. Aguieiras, Martina C. C. Pinto, Fernanda A. Tavares, Priscila R. da Silva, Roberto Fernandez-Lafuente, Sara Arana-Pena, Jose Carlos Pinto, Charles L. B. Assuncao, Jose Andre C. da Silva, Denise M. G. Freire
Summary: This study successfully synthesized biolubricants from by-products of soybean oil processing using the lipase from Candida rugosa, showing high conversion rates and improved efficiency through immobilization. The products demonstrated good lubricant properties, indicating a potential environmentally friendly alternative to petroleum-based lubricants.
Article
Materials Science, Multidisciplinary
Nengwen Gao, Jing Liu, Xiaoli Wang, Yu Zhang
Summary: This study investigates the immobilization of lipase on ceramic membranes using modification and cross-linking methods. The immobilized lipases show higher catalytic activity and stability, making them suitable for applications in high-temperature and alkaline environments.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Biology
Prasanna J. Patil, Subodh A. Kamble, Maruti J. Dhanavade, Xin Liang, Chengnan Zhang, Xiuting Li
Summary: This study used molecular modeling approaches to investigate the interaction between CRL and the specific MOF ZIF-8. The results of molecular docking analysis showed that ZIF-8 was located at the active site pocket of CRL and formed hydrogen bonds with specific amino acids. The MD simulation analysis demonstrated the stability of the CRL-ZIF-8 docked complex and the maintenance of all interactions throughout the simulation. These findings contribute to the understanding of the molecular mechanisms and potential applications of immobilized CRL for various industries.
Article
Agriculture, Multidisciplinary
Yifei Zhang, Guangzheng Ma, Shushu Wang, Binbin Nian, Yi Hu
Summary: This study achieved efficient immobilization of Candida rugosa lipase on commercial macroporous resins, resulting in an efficient catalyst for the synthesis of phytosterol esters. A solvent-free strategy using oleic acid as the esterification reaction medium yielded a high yield of ester synthesis. This immobilization strategy provides new possibilities for the high-efficiency production of pine sterol esters and other food source nutrients.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Materials Science, Multidisciplinary
Elif Ozyilmaz, Ozge Caglar, Idris Sargin, Gulsin Arslan
Summary: The study successfully prepared a new support material for encapsulating Candida rugosa lipase by combining edible mushroom-derived CQDs and ZIF-8 crystals, with higher enzyme loading efficiency compared to in-situ encapsulation. Structural, morphological, and spectrophotometric analyses showed that CQDs and the enzyme were physically entrapped within the three-dimensional structures of ZIF-8.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Biotechnology & Applied Microbiology
Shushu Wang, Shan Li, Runtang Liu, Wei Zhang, Huajin Xu, Yi Hu
Summary: In this study, Candida rugosa lipase (CRL) was activated and covalently immobilized on a nanocomposite material using surfactants. The nanocomposite material, fabricated by combining magnetic nanoparticles with chitosan, proved to be an ideal support for enzyme immobilization. The immobilized CRL showed improved stability and reusability.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Materials Science, Biomaterials
Hongbo Suo, Huining Geng, Lu Zhang, Guoyun Liu, Hui Yan, Rui Cao, Jiahao Zhu, Yi Hu, Lili Xu
Summary: Enzymatic esterification is an important process in chemistry and biotechnology. In this study, lipase was immobilized on an ionic liquid-modified magnetic metal-organic framework and used for the synthesis of isoamyl acetate. The immobilized lipase showed higher activity, anti-denaturant ability, and reusability compared to other samples. The synthesized composite material exhibited good potential in lipase immobilization with enhanced catalytic ability and stability.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Nanoscience & Nanotechnology
Yongfa Cheng, Oi-Ming Lai, Chin-Ping Tan, Worawan Panpipat, Ling-Zhi Cheong, Cai Shen
Summary: Immobilization can improve the stability and reusability of lipases, but may also lead to conformational changes that decrease catalytic activity. In this study, grafting proline onto UIO-66 crystals for immobilization of Candida rugosa lipase showed enhanced enzyme activity and better recycling capabilities, indicating improved catalytic efficiency.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Xiangxuan Meng, Jiafu Shi, Zhenhua Wu, Wenping Li, Chen Yang, Ting Qiu, Zhongyi Jiang
Summary: A bioactive covalent organic framework (COF) capsule was successfully fabricated through enzyme-induced growth and crystallization of COFs on a sacrificial template, enabling sustainable lactate synthesis. The COF capsule's unique structure provided a highly tunable space for enzyme immobilization. By optimizing the synthesis time of COF and the amount of enzyme, the bio-COF capsules were able to retain 70% of their initial activity under reaction conditions at pH 6 and 35 degrees C. The confinement of enzymes within the capsule wall significantly improved operational stability and organic solvent tolerance.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Biotechnology & Applied Microbiology
Yuan Ji, Zhengzhang Wu, Peng Zhang, Meng Qiao, Yi Hu, Baoxing Shen, Bingzhi Li, Xing Zhang
Summary: The study successfully encapsulated lipase and magnetic nanoparticles into ZIF-8 composite material using a mild and quick one-pot strategy, achieving high immobilization yield. The resulting magnetic MOF composite demonstrated excellent resistance to harsh environments, simplifying complex downstream operations, and maintaining high activity even after multiple reuse cycles.
BIOCHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Physical
Nurfadhila Nasya Ramlee, Rosli Md Illias, Roshanida A. Rahman, Susilawati Toemen, Rangabhashiyam Selvasembian, Rabi'atul Adawiyah Ahmad, Nor Hasmaliana Abdul Manas, Nur Izyan Wan Azelee
Summary: Enzyme immobilization on inorganic materials is gaining more attention due to the potential characteristics of high surface area-to-volume ratios, increasing enzyme loading efficiency. In this study, Candida rugosa lipase was successfully immobilized on a metal oxide hybrid support, showing high thermal stability and wide pH stability range. The immobilized enzyme also demonstrated high tolerance in solvents compared to free enzyme.
Article
Biochemistry & Molecular Biology
Otavio Domingues, Daniela Remonatto, Leticia Karen dos Santos, Julian Paul Martinez Galan, Danilo Luiz Flumignan, Ariela Veloso de Paula
Summary: This study successfully prepared functionalized maghemite nanoparticles for immobilization of Candida rugosa lipase (CRL) and evaluated its potential in the hydrolysis of waste cooking oil (WCO) and biodiesel production. The immobilized derivative showed high catalytic activity, and after immobilization, the nanoparticles became more dispersed, which is advantageous for catalytic reactions.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Applied
Gulay Bayramoglu, Omur Celikbicak, Murat Kilic, M. Yakup Arica
Summary: Magnetic chitosan beads grafted with polydopamine were used to immobilize Candida rugosa lipase, leading to improved thermal and storage stability compared to the free enzyme. The immobilized lipase showed significant changes in catalytic properties and high conversion rates in esterification reactions, indicating its potential for various biotechnological applications.
Article
Biochemistry & Molecular Biology
Anja Heyse, Miriam M. Gossmann, Patrick Giefer, Patrizia Gaebel, Udo Fritsching, Anja M. Wagemans, Stephan Drusch
Summary: Fouling due to biomolecule adsorption remains a drawback for membrane emulsification. This study investigated the fouling effect on the membrane and the modified enzyme. Through experiments and simulations, it was found that increasing lipase concentration led to higher fouling and decreased wetting of the membrane. The pH of the lipase solution also affected the microstructure of the foulant layer. Despite enzyme mass loss, the structural and functional characteristics of lipase were not significantly affected.
PROCESS BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Zeping Lu, Mei Chen, Tongtong Jin, Binbin Nian, Yi Hu
Summary: Ionic liquids (ILs) are used as chemical modifiers to improve the efficiency, activity, and stability of enzymes. This study investigated the impact of ILs with different chain lengths on the enzymatic properties of Candida antarctica lipase B (CALB) and found that ILs significantly influenced CALB's absorption orientation. Molecular dynamics simulations showed that ILs with suitable chain lengths formed strong interactions with CNTs and ILs, stabilizing CALB's open state and improving its activity and stability. This study provides insights into the design of green modifiers for better immobilized enzymes and lays the groundwork for future research on IL modifiers.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Multidisciplinary
Hadi Ahmadi, Ehsan Hosseini, Withita Cha-Umpong, Mojtaba Abdollahzadeh, Asghar Habibnejad Korayem, Amir Razmjou, Vicki Chen, Mohsen Asadnia
Summary: Research has found that tannic acid in graphene oxide nanochannels can act as a natural ion trapper, excluding lithium ions from other monovalent cations to produce a lithium-rich feed. The inexpensive tannic acid-graphene oxide membrane shows superior lithium trapping efficiency, with lithium having a significant lithiophilic element.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Engineering, Chemical
Milton Chai, Yun Ye, Amir Razmjou, Vicki Chen
Summary: The study demonstrates that membrane vibration can significantly enhance the mass transfer performance in forward osmosis, with flux improvement of over 43% in different membrane configurations. Furthermore, membrane vibration can help mitigate the effects of accelerated cake-enhanced concentration polarization.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Article
Engineering, Chemical
Mohammad Zakertabrizi, Ehsan Hosseini, Asghar Habibnejad Korayem, Amir Razmjou, Anthony G. Fane, Vicki Chen
Summary: Recent research has revealed the physical potential of anhydrous proton transfer within two-dimensional nanosheets, achieving full proton selectivity and ultrafast transmission speed through the Grotthuss mechanism. These findings not only guide the manufacturing of a new generation of sustainable nanochannels, but also advance pioneering technologies surrounding hydrogen energy.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Review
Materials Science, Multidisciplinary
Asieh Soozanipour, Hessamaddin Sohrabi, Farbod Abazar, Alireza Khataee, Abdollah Noorbakhsh, Mohsen Asadnia, Asghar Taheri-Kafrani, Mir Reza Majidi, Amir Razmjou
Summary: Nanochannels offer advantages in flexibility, low cost, and ion selectivity for ion separation. Research on nanochannels focuses on design factors, ion transport mechanisms, and applications.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Review
Materials Science, Multidisciplinary
Hamid Amiri, Mohsen Khosravi, Mojtaba Ejeian, Amir Razmjou
Summary: The future of energy relies on batteries like VRFBs, with membranes playing a crucial role in controlling proton transport and preventing mixing in VRFBs. While Nafion membranes have made breakthroughs, their high cost and low selectivity make them unsuitable for VRFBs, suggesting sulfonated aromatic hydrocarbon polymers as a cost-effective alternative.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Materials Science, Multidisciplinary
Sajad Abolpour Moshizi, Hamed Moradi, Shuying Wu, Zhao Jun Han, Amir Razmjou, Mohsen Asadnia
Summary: In this study, a novel flow sensor based on PVA hydrogel nanocomposites and graphene nanosheets is developed, showing high sensitivity and extremely low velocity detection capability. The sensor is highly sensitive to tiny stimuli underwater and suitable for biomedical applications.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Chemistry, Multidisciplinary
Mojtaba Abdollahzadeh, Milton Chai, Ehsan Hosseini, Mohammad Zakertabrizi, Munirah Mohammad, Hadi Ahmadi, Jingwei Hou, Sean Lim, Asghar Habibnejad Korayem, Vicki Chen, Mohsen Asadnia, Amir Razmjou
Summary: This study introduces a highly tunable design concept to fabricate monovalent ion-selective membranes with asymmetric sub-nanometer pores and implanted energy barriers. The measurements show exceptional selectivity and ion rectification, which holds significance in sensing, energy storage, and separation technologies.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Analytical
Salman Jalalifar, Afsaneh Kashizadeh, Ishmam Mahmood, Andrew Belford, Nicolle Drake, Amir Razmjou, Mohsen Asadnia
Summary: This paper proposes a robust and waterproof sensor-based device to detect distress in swimmers at varying depths and different types of water environments. The device comprises heart rate, blood oxygen level, movement, and depth sensors that can operate independently or together to detect dangerous situations. The data from the sensors are sent to a microcontroller and compared to adjustable threshold values to activate an alarming system and send messages to a lifeguard. The device was thoroughly tested and demonstrated its capability in detecting potentially hazardous aquatic situations.
Article
Chemistry, Analytical
Mojtaba Abdollahzadeh, Bita Bayatsarmadi, Mikko Vepsalainen, Amir Razmjou, Mohsen Asadnia
Summary: In this study, a highly stable Li+ selective electrode was produced using NiHAB MOF, demonstrating significantly improved capacitance of the sensor with a low drift rate, low limit of detection, and high sensitivity. This research offers a solution to the persistent issues of solid-contact sensors and paves the way for the miniaturization of sensors for real-life applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biochemistry & Molecular Biology
Atiyeh Bashiri, Arash Nikzad, Reza Maleki, Mohsen Asadnia, Amir Razmjou
Summary: The demand for rare earth elements (REEs) has increased due to their high potential applications in modern industry. However, their separation is difficult due to their similar properties. This review focuses on membrane separation technology (MST) as an environmentally friendly approach to extract REEs. The mechanisms of REEs separation through membranes are discussed, and potential directions for future studies are suggested.
Article
Engineering, Chemical
Sayed Mukit Hossain, Idris Ibrahim, Youngwoo Choo, Amir Razmjou, Gayathri Naidu, Leonard Tijing, Jong-Ho Kim, Ho Kyong Shon
Summary: Titanium-type lithium-ion sieves (LISs) are potential adsorbents for Li+ extraction due to their structural stability and high adsorption capacity. The sludge-generated LISs synthesized using environment-friendly anatase titania exhibited high Li+ adsorption capacity and recycling stability. These findings suggest promising industrial applications.
Article
Chemistry, Physical
Asieh Soozanipour, Asghar Taheri-Kafrani, Amir Razmjou, Mohsen Asadnia
Summary: In this study, hyper-branched poly (amide amine) (PAMAM) nanoparticles were conjugated with hyaluronidase (Hyal) to create a stable nano-biocatalyst for hyaluronic acid (HA) degradation. The results showed that the Hyal-PAMAM nanocomplex had higher enzymatic activity at optimum pH, temperature, and storage time compared to free enzyme. In addition, computational screening further confirmed the experimental results. This strategy of combining Hyal and PAMAM holds great promise for applications in biomedical, sensing, and industrial catalysis.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biochemistry & Molecular Biology
Anna Siekierka, Marek Bryjak, Amir Razmjou, Wojciech Kujawski, Aleksandar N. Nikoloski, Ludovic F. Dumee
Summary: The mass production of lithium-ion batteries and lithium-rich e-products has created an unprecedented demand for lithium resources. Current production technologies are environmentally impactful and energy-intensive, but the emergence of selective membrane materials and electrochemical processes offers more sustainable alternatives.
Article
Chemistry, Multidisciplinary
M. Asadniaye Fardjahromi, H. Nazari, S. M. Ahmadi Tafti, A. Razmjou, S. Mukhopadhyay, M. E. Warkiani
Summary: The use of nano-metal organic framework (nanoMOF) scaffolds presents a promising opportunity to enhance the properties of bone and wound tissue engineering scaffolds due to their unique characteristics such as high internal surface areas, high porosity, good mechanical stability, biocompatibility, and tunability. Incorporating nano-MOFs into scaffolds has been shown to be favorable for regenerating imperfect tissues, offering advantages such as high antibacterial activity, high drug loading capacity, and controlled drug release. However, challenges and clinical barriers need to be addressed for the implementation of these nanomaterials in orthopedic and wound clinics.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Mahsa Golmohammadi, Meysam Habibi, Sima Rezvantalab, Yasin Mehdizadeh Chellehbari, Reza Maleki, Amir Razmjou
Summary: Lithium ions are crucial in energy storage, and finding suitable lithium-ion-conductive membranes is an important issue. This study investigated the mechanism of an ion-selective membrane and the efficiency of a perovskite-based membrane using MD simulation. The results showed that pH, ambient conditions, and temperature affected the pore sizes and lithium ion transmission through the membrane.
