Double-sides sticking mechanism of vinblastine interacting with α,β-tubulin to get activity against cancer cells

Structural Basis and Mechanism of Chiral Benzedrine Molecules Interacting With Third Dopamine Receptor

(2016) Ming Wang et al.   CHIRALITY

Molecular dynamics simulation of d-Benzedrine transmitting through molecular channels within D3R

(2016) Wei Xie et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Theoretical insight into the structural mechanism for the binding of vinblastine with tubulin

(2015) Shaoming Chi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Synthesis and Biological Evaluation of a New Series of Highly Functionalized 7′-homo-Anhydrovinblastine Derivatives

(2013) Olga Gherbovet et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potent Vinblastine C20′ Ureas Displaying Additionally Improved Activity Against a Vinblastine-Resistant Cancer Cell Line

(2013) Timothy J. Barker et al.   ACS Medicinal Chemistry Letters

The Key Residues of Active Sites on the Catalytic Fragment for Paclitaxel Interacting with Poly (ADP-Ribose) Polymerase

(2012) Yue Wang et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Structural insight into the mechanism of epothilone A bound to beta-tubulin and its mutants at Arg282Gln and Thr274Ile

(2012) Guojun Shi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

A Remarkable Series of Vinblastine Analogues Displaying Enhanced Activity and an Unprecedented Tubulin Binding Steric Tolerance: C20′ Urea Derivatives

(2012) Erick K. Leggans et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular docking and pharmacogenomics of Vinca alkaloids and their monomeric precursors, vindoline and catharanthine

(2011) Serkan Sertel et al.   BIOCHEMICAL PHARMACOLOGY

Molecular dynamics simulation and density functional theory studies on the active pocket for the binding of paclitaxel to tubulin

(2011) Sichuan Xu et al.   JOURNAL OF MOLECULAR MODELING

10′-Fluorovinblastine and 10′-Fluorovincristine: Synthesis of a Key Series of Modified Vinca Alkaloids

(2011) Hiroaki Gotoh et al.   ACS Medicinal Chemistry Letters

g_wham—A Free Weighted Histogram Analysis Implementation Including Robust Error and Autocorrelation Estimates

(2010) Jochen S. Hub et al.   Journal of Chemical Theory and Computation

Microtubule-Binding Natural Products for Cancer Therapy

(2010) Qing-Xi Yue et al.   PLANTA MEDICA

Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity

(2009) Holly Freedman et al.   Journal of Chemical Information and Modeling

Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

(2009) Hayato Ishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Free Energy for the Permeation of Na+and Cl−Ions and Their Ion-Pair through a Zwitterionic Dimyristoyl Phosphatidylcholine Lipid Bilayer by Umbrella Integration with Harmonic Fourier Beads

(2009) Ilja V. Khavrutskii et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and biological evaluation of C-12′ substituted vinflunine derivatives

(2008) Lei Xin Sheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vinflunine: clinical perspectives of an emerging anticancer agent

(2008) Adrian Yun-San Yip et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation