Enhanced interaction between SEC2 mutant and TCR Vβ induces MHC II–independent activation of T cells via PKCθ/NF-κB and IL-2R/STAT5 signaling pathways
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Title
Enhanced interaction between SEC2 mutant and TCR Vβ induces MHC II–independent activation of T cells via PKCθ/NF-κB and IL-2R/STAT5 signaling pathways
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 293, Issue 51, Pages 19771-19784
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2018-10-24
DOI
10.1074/jbc.ra118.003668
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- The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation
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- The bacterial superantigen and superantigen-like proteins
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