It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate

Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions

(2018) Georg K. A. Hochberg et al.   SCIENCE

Multiple oligomeric structures of a bacterial small heat shock protein

(2016) Nandini Mani et al.   Scientific Reports

A First Line of Stress Defense: Small Heat Shock Proteins and Their Function in Protein Homeostasis

(2015) Martin Haslbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes

(2015) Tilly Fleckenstein et al.   MOLECULAR CELL

Lanosterol reverses protein aggregation in cataracts

(2015) Ling Zhao et al.   NATURE

Pharmacological chaperone for  -crystallin partially restores transparency in cataract models

(2015) L. N. Makley et al.   SCIENCE

A Novel Mechanism for Small Heat Shock Proteins to Function as Molecular Chaperones

(2015) Kaiming Zhang et al.   Scientific Reports

Replica Exchange Molecular Dynamics Simulations Provide Insight into Substrate Recognition by Small Heat Shock Proteins

(2014) Sunita Patel et al.   BIOPHYSICAL JOURNAL

The structured core domain of  B-crystallin can prevent amyloid fibrillation and associated toxicity

(2014) G. K. A. Hochberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human small heat shock proteins: Protein interactomes of homo- and hetero-oligomeric complexes: An update

(2013) André-Patrick Arrigo   FEBS LETTERS

One size does not fit all: The oligomeric states of αB crystallin

(2013) Scott P. Delbecq et al.   FEBS LETTERS

Cryoelectron Microscopy Analysis of Small Heat Shock Protein 16.5 (Hsp16.5) Complexes with T4 Lysozyme Reveals the Structural Basis of Multimode Binding

(2013) Jian Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Unusual Dimeric Small Heat Shock Protein Provides Insight into the Mechanism of This Class of Chaperones

(2013) Eman Basha et al.   JOURNAL OF MOLECULAR BIOLOGY

Tobacco mitochondrial small heat shock protein NtHSP24.6 adopts a dimeric configuration and has a broad range of substrates

(2012) Keun-Pill Kim et al.   BMB Reports

Dissecting Heterogeneous Molecular Chaperone Complexes Using a Mass Spectrum Deconvolution Approach

(2012) Florian Stengel et al.   CHEMISTRY & BIOLOGY

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The evolution, function, structure, and expression of the plant sHSPs

(2012) Elizabeth R. Waters   JOURNAL OF EXPERIMENTAL BOTANY

Structural Studies on the Oligomeric Transition of a Small Heat Shock Protein, StHsp14.0

(2012) Yuya Hanazono et al.   JOURNAL OF MOLECULAR BIOLOGY

Alternative bacterial two-component small heat shock protein systems

(2012) A. Bepperling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, from Schizosaccharomyces pombe

(2012) Yuya Hanazono et al.   STRUCTURE

Quaternary Dynamics of αB-Crystallin as a Direct Consequence of Localised Tertiary Fluctuations in the C-Terminus

(2011) Andrew J. Baldwin et al.   JOURNAL OF MOLECULAR BIOLOGY

αB-Crystallin Polydispersity Is a Consequence of Unbiased Quaternary Dynamics

(2011) Andrew J. Baldwin et al.   JOURNAL OF MOLECULAR BIOLOGY

Large Potentials of Small Heat Shock Proteins

(2011) Evgeny V. Mymrikov et al.   PHYSIOLOGICAL REVIEWS

The Polydispersity of αB-Crystallin Is Rationalized by an Interconverting Polyhedral Architecture

(2011) Andrew J. Baldwin et al.   STRUCTURE

Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

(2011) Eman Basha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Collision Cross Sections of Proteins and Their Complexes: A Calibration Framework and Database for Gas-Phase Structural Biology

(2010) Matthew F. Bush et al.   ANALYTICAL CHEMISTRY

The Quaternary Organization and Dynamics of the Molecular Chaperone HSP26 Are Thermally Regulated

(2010) Justin L.P. Benesch et al.   CHEMISTRY & BIOLOGY

Mechanistic Differences between Two Conserved Classes of Small Heat Shock Proteins Found in the Plant Cytosol

(2010) Eman Basha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Heat Shock Response: Life on the Verge of Death

(2010) Klaus Richter et al.   MOLECULAR CELL

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quaternary dynamics and plasticity underlie small heat shock protein chaperone function

(2010) F. Stengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational analysis and design of cross-strand disulfides in antiparallel β-sheets

(2010) S. Indu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure and Mechanism of Protein Stability Sensors: Chaperone Activity of Small Heat Shock Proteins

(2009) Hassane S. Mchaourab et al.   BIOCHEMISTRY

Substrate binding site flexibility of the small heat shock protein molecular chaperones

(2009) N. Jaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-Time Monitoring of Protein Complexes Reveals their Quaternary Organization and Dynamics

(2008) Alexander J. Painter et al.   CHEMISTRY & BIOLOGY

Insights into Small Heat Shock Protein and Substrate Structure during Chaperone Action Derived from Hydrogen/Deuterium Exchange and Mass Spectrometry

(2008) Guilong Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Average protein density is a molecular-weight-dependent function

(2004) Hannes Fischer et al.   PROTEIN SCIENCE