Article
Pediatrics
Claire A. Ostertag-Hill, John B. Mulliken, Belinda H. Dickie, Steven J. Fishman
Summary: This study retrospectively evaluated 43 surgeries performed on 31 patients with vulvar VMs between 1998 and 2022. The majority of patients had extensive VMs and presented with symptoms such as pain, aesthetic concerns, functional impairment, bleeding, and cellulitis. Single resection surgery can successfully treat patients with focal VMs, while those with extensive VMs may require multiple partial resections or a combination of sclerotherapy and resection for long-term control.
JOURNAL OF PEDIATRIC SURGERY
(2023)
Article
Obstetrics & Gynecology
Andreas Kalampalikis, Sofia Ivanidou, Lina Michala
Summary: Labial fusion in adolescence is often caused by lichen sclerosus, presenting with symptoms like pruritus, urinary problems, and inflamed inclusion cysts. Treatment involves labial separation surgery, use of glucocorticoid cream, and emollient agents. Early identification and treatment of LS are crucial to prevent distortion of vulvar anatomy.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Oncology
Emily F. Thompson, Kathryn Shum, Richard W. C. Wong, Giorgia Trevisan, Janine Senz, Jutta Huvila, Samuel Leung, David G. Huntsman, C. Blake Gilks, Jessica N. McAlpine, Lynn Hoang, Amy Jamieson
Summary: In patients with HPV-independent p53 abnormal vulvar squamous cell carcinoma, the presence of differentiated vulvar intra-epithelial neoplasia (dVIN) or abnormal p53 immunohistochemistry on resection margins is associated with increased disease recurrence, regardless of the distance of the invasive margins.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Urology & Nephrology
Funda Gungor Ugurlucan, Cenk Yasa, Inci Sema Tas, Isik Aslay, Onay Yalcin
Summary: Labial fusion or adhesion can rarely occur postmenopausal and may lead to urinary retention, which may not be completely resolved with topical estrogen treatment, requiring surgical intervention in some cases.
AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL UROLOGY
(2021)
Article
Biochemistry & Molecular Biology
Alenka Vesel, Nina Recek, Rok Zaplotnik, Albert Kurincic, Katja Kuzmic, Lidija Fras Zemljic
Summary: This study presents a method for immobilizing an antibacterial chitosan coating on polymeric urinary medical catheters using a two-step plasma-treatment procedure. The plasma treatment modifies the polymer surface to enhance the adsorption and binding of chitosan, resulting in a successful immobilization of the coating.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Polymer Science
Yongwei Cai, Hong Yang, Jianxiang Li, Ronghua Gu, Yuhang Dong, Qi Zhao, Yao Chen, Yuanju Li, Ruru Wang
Summary: Catheter-associated urinary tract infections (CAUTI) are responsible for 40% of all hospital-acquired infections, with over 1 million cases occurring annually in the United States and Europe. This study developed a novel antibacterial coating using silver nanoparticles poly(acrylamide)-chitosan-polyvinylpyrrolidone (AgNPs-PAAm-CS-PVP) composite hydrogel on latex urinary catheters. The results demonstrated that the hydrogel had long-lasting antibacterial activity and decreased bacterial adhesion.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Cell Biology
Baris Boyraz, Ryosuke Tajiri, Rofieda R. Alwaqfi, Arnaud Da Cruz Paula, Qiqi Ye, G. Petur Nielsen, Yin P. Hung, Esther Oliva, Britta Weigelt, Masanori Hisaoka, Jaclyn C. Watkins
Summary: Angiomyofibroblastoma (AMF), a rare benign vulvovaginal mesenchymal tumour, is difficult to diagnose due to overlapping features with other vulvar mesenchymal tumours. This study found that the majority of AMFs have recurrent MTG1-CYP2E1 fusion transcripts, which can aid in the diagnosis.
Article
Materials Science, Multidisciplinary
Klemen Bohinc, Lora Kukic, Roman Stukelj, Anamarija Zore, Anze Abram, Tin Klacic, Davor Kovacevic
Summary: The application of catheters to the urinary tract is associated with nosocomial infections, which are one of the most common types of infections in hospitals and healthcare facilities. Coating catheter surfaces with polyelectrolyte multilayers has been shown to reduce bacterial adhesion and biofilm formation, with PSS-terminated multilayers exhibiting the lowest bacterial adhesion. The surface charge plays a crucial role in bacterial adhesion on both uncoated and coated PVC catheter surfaces, while roughness and hydrophobicity show similar properties.
Article
Materials Science, Biomaterials
Qin Yao, Binghai Chen, Jiaxiang Bai, Wenbo He, Xu Chen, Dechun Geng, Guoqing Pan
Summary: This study successfully functionalized catheters using metal-catechol-assisted mussel chemistry, adding antimicrobial peptides to prevent infection and encrustation long-term.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Editorial Material
Obstetrics & Gynecology
Monica Bronte Anaut, Javier Arredondo Montero, Eva Arpa Nadal, Rosa Guarch Troyas
Summary: Vulvar eosinophilic folliculitis is a rare diagnosis that should be considered in cases of chronic vulvar lesions. In the differential diagnosis, condyloma acuminatum and herpetic folliculitis should be included.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Biochemistry & Molecular Biology
Guilherme Gainett, Benjamin C. Klementz, Pola O. Blaszczyk, Heather S. Bruce, Nipam H. Patel, Prashant P. Sharma
Summary: In this study, we investigated the function of lab and Dfd in Chelicerata. We found that lab is involved in tissue maintenance of pedipalps and patterning leg 1 identity, while Dfd is important for patterning the first walking leg identity. Additionally, we discovered that the double knockdown of lab and Dfd resulted in homeotic transformations of pedipalps and walking legs.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Obstetrics & Gynecology
Alexander B. Olawaiye, Mauricio A. Cuello, Linda J. Rogers
Summary: Vulvar cancer is a rare gynecological malignancy that primarily affects postmenopausal women. The most effective strategy to reduce its incidence is the timely treatment of predisposing and preneoplastic lesions. Treatment should be individualized based on histology and surgical staging, with surgery being the main approach.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Article
Biotechnology & Applied Microbiology
E. A. Koroleva, A. V. Soloveva, E. Y. Morgunova, L. N. Kapotina, S. I. Luyksaar, S. V. Luyksaar, N. E. Bondareva, S. A. Nelubina, N. L. Lubenec, N. A. Zigangirova, A. L. Gintsburg
Summary: Uropathogenic Escherichia coli (UPEC) infection, which has become a serious problem due to antibiotic resistance, may potentially be treated with the compound Fluorothiazinon. Our study showed that Fluorothiazinon suppressed UPEC's virulence factors and improved survival and bacterial load in rodent models. If similar results are found in clinical trials, Fluorothiazinon may serve as a new drug against UPEC.
JOURNAL OF ANTIBIOTICS
(2023)
Article
Agriculture, Dairy & Animal Science
Flor-Anita Corredor, Leticia P. Sanglard, Jason W. Ross, Aileen F. Keating, Richard J. Leach, Nick V. L. Serao
Summary: Vulva score as an indicator trait has potential for improving reproductive efficiency in first-parity performance, with genetic and genomic analyses providing valuable insights into its application.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Urology & Nephrology
James M. Jones, Cole Gannett, Mattie Jones, Ervelyn Winata, Meihua Zhu, Lisa Buckley, Jack Lazar, Jason C. Hedges, Simon J. McCarthy, Hua Xie
Summary: This study investigated a novel transurethral hemostatic catheter device with an integrated chitosan endoluminal hemostatic dressing. The study demonstrated the feasibility of transurethral deployment of the device in vivo and found that it was noninferior to control catheters in terms of hemostasis.