Journal
INTERNATIONAL JOURNAL OF NANOMEDICINE
Volume 13, Issue -, Pages 6143-6176Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJN.S172907
Keywords
fullerenes; nanoparticles; drug delivery; personalized medicine; ab initio; molecular dynamics
Funding
- international project entitled Self-navigated integrin receptors seeking thermally-smart multifunctional few-layer graphene-encapsulated magnetic nanoparticles for molecular MRI-guided anticancer treatments in real time personalized nanomedicine (acronym
- PL-Grid Infrastructure
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There are several reasons why nanotechnology is currently considered as the leader among the most intensively developing research trends. Nanomatter often exhibits new properties, other than those of the morphology of a continuous solid. Also, new phenomena appear at the nanoscale, which are unknown in the case of microcrystalline objects. For this reason, nanomaterials have already found numerous applications that are described in this review. However, among intensively developed various branches of nanotechnology, nanomedicine and pharmacology stand out particularly, which opens new possibilities for the development of these disciplines, gives great hope for the creation of new drugs in which toxicological properties are reduced to a minimum, reduces the doses of medicines, offers targeted treatment and increases diagnostic possibilities. Nanotechnology is the source of a great revolution in medicine. It gives great hope for better and faster treatment of many diseases and gives hope for a better tomorrow. However, the creation of new nanodrugs requires a special understanding of the properties of nanoparticles. This article is a review work which determines and describes the way of creating new nanodrugs from ab initio calculations by docking and molecular dynamic applications up to a new medicinal product, as a proposal for the personalized medicine, in the early future.
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