Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells

Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer.

(2018) Imre Hunyor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promoters

(2018) Norio Suzuki et al.   EXPERIMENTAL CELL RESEARCH

Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

(2018) Emily Harris et al.   Marine Drugs

The regulation of transcriptional repression in hypoxia

(2017) Miguel A.S. Cavadas et al.   EXPERIMENTAL CELL RESEARCH

Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction

(2016) Andrew K. L. Goey et al.   JOURNAL OF NATURAL PRODUCTS

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer

(2016) Caroline Wigerup et al.   PHARMACOLOGY & THERAPEUTICS

Inhibition of the HIF1α-p300 interaction by quinone- and indandione-mediated ejection of structural Zn(II)

(2015) Madura K.P. Jayatunga et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α

(2015) Susanna T. S. Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Obstructive sleep apnea promotes cancer development and progression: a concise review

(2015) Jie Cao et al.   Sleep and Breathing

REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia

(2015) Miguel A. S. Cavadas et al.   Scientific Reports

Intermittent Hypoxia-induced Changes in Tumor-associated Macrophages and Tumor Malignancy in a Mouse Model of Sleep Apnea

(2014) Isaac Almendros et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response

(2014) S R McKeown   BRITISH JOURNAL OF RADIOLOGY

Association between sleep disordered breathing and aggressiveness markers of malignant cutaneous melanoma

(2014) M.-A. Martinez-Garcia et al.   EUROPEAN RESPIRATORY JOURNAL

Increased Prevalence of Sleep-Disordered Breathing in Adults

(2013) P. E. Peppard et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Allosteric Control of βII-Tryptase by a Redox Active Disulfide Bond

(2013) Kristina M. Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts

(2013) Daniele M. Gilkes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intermittent hypoxia increases melanoma metastasis to the lung in a mouse model of sleep apnea

(2013) Isaac Almendros et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Sleep-disordered Breathing and Cancer Mortality

(2012) F. Javier Nieto et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bleach gel: A simple agarose gel for analyzing RNA quality

(2012) Patrick S. Aranda et al.   ELECTROPHORESIS

Intermittent hypoxia enhances cancer progression in a mouse model of sleep apnoea

(2012) I. Almendros et al.   EUROPEAN RESPIRATORY JOURNAL

Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea

(2012) Isaac Almendros et al.   SLEEP MEDICINE

Effects of different acute hypoxic regimens on tissue oxygen profiles and metabolic outcomes

(2011) Christian Reinke et al.   JOURNAL OF APPLIED PHYSIOLOGY

Tissue Oxygenation in Brain, Muscle, and Fat in a Rat Model of Sleep Apnea: Differential Effect of Obstructive Apneas and Intermittent Hypoxia

(2011) Isaac Almendros et al.   SLEEP

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene

(2010) F M Buffa et al.   BRITISH JOURNAL OF CANCER

Angiogenesis Inhibitors: Current Strategies and Future Prospects

(2010) K. M. Cook et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

(2010) Amaya Ortiz-Barahona et al.   NUCLEIC ACIDS RESEARCH

Intermittent and sustained hypoxia induce a similar gene expression profile in human aortic endothelial cells

(2010) Vsevolod Y. Polotsky et al.   PHYSIOLOGICAL GENOMICS

Intermittent hypoxia is an angiogenic inducer for endothelial cells: role of HIF-1

(2009) Sébastien Toffoli et al.   ANGIOGENESIS

Epidithiodiketopiperazines Block the Interaction between Hypoxia-inducible Factor-1α (HIF-1α) and p300 by a Zinc Ejection Mechanism

(2009) Kristina M. Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-inducible Factor-1α Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion

(2007) Elisabeth L. Pagé et al.   MOLECULAR BIOLOGY OF THE CELL