Extracellular Matrix Influencing HGF/c-MET Signaling Pathway: Impact on Cancer Progression

ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma

(2018) Heydi Noriega-Guerra et al.   EXPERIMENTAL CELL RESEARCH

Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma

(2018) Lucia Demkova et al.   Molecular Cancer

Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2): Emerging key players in epithelial integrity and cancer

(2018) Hiroaki Kataoka et al.   PATHOLOGY INTERNATIONAL

Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer

(2017) Arman Jahangiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

(2017) Mariela Natacha González et al.   Skeletal Muscle

Inflammatory cytokine production in tumor cells upon chemotherapy drug exposure or upon selection for drug resistance

(2017) Derek W. Edwardson et al.   PLoS One

The role of the HGF/Met axis in mesothelioma

(2016) Thivyan Thayaparan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells

(2016) Chi Hoon Park et al.   BMC CANCER

The role of HGF/c-MET signaling pathway in lymphoma

(2016) Bao Quoc Lam et al.   Journal of Hematology & Oncology

The regulatory role of heparin on c-Met signaling in hepatocellular carcinoma cells

(2016) Evin İşcan et al.   Journal of Cell Communication and Signaling

HGF-MET as a breast cancer biomarker

(2015) Shuying Liu   Aging-US

Genomic Instability Causes HGF Gene Activation in Colon Cancer Cells, Promoting Their Resistance to Necroptosis

(2015) Danushka Seneviratne et al.   GASTROENTEROLOGY

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion

(2015) Hui-Hui Cao et al.   Molecular Cancer

Anticoagulant therapy of cancer patients: Will patient selection increase overall survival?

(2015) Henri Versteeg et al.   THROMBOSIS AND HAEMOSTASIS

Hepatocyte growth factor increases the invasive potential of PC-3 human prostate cancer cells via an ERK/MAPK and Zeb-1 signaling pathway

(2015) YILI HAN et al.   Oncology Letters

Remodeling Components of the Tumor Microenvironment to Enhance Cancer Therapy

(2015) Vasiliki Gkretsi et al.   Frontiers in Oncology

Adipose-derived mesenchymal stem cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling.

(2015) Vincenzo Eterno et al.   Oncotarget

Tumour angiogenesis and repulsive guidance molecule b: A role in HGF- and BMP-7-mediated angiogenesis

(2014) ANDREW J. SANDERS et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cancer-associated fibroblasts from invasive breast cancer have an attenuated capacity to secrete collagens

(2014) ZHIXUAN FU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Biology of the Extracellular Matrix

(2014) Beatrice Yue   JOURNAL OF GLAUCOMA

The effect of low molecular weight heparin on survival in cancer patients: an updated systematic review and meta-analysis of randomized trials: reply

(2014) D. Sanford et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Tumor-Associated Hyaluronan Limits Efficacy of Monoclonal Antibody Therapy

(2014) N. C. Singha et al.   MOLECULAR CANCER THERAPEUTICS

Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters

(2014) Alexandra Naba et al.   eLife

Mechanisms of Hepatocyte Growth Factor Activation in Cancer Tissues

(2014) Makiko Kawaguchi et al.   Cancers

Molecular engineering of glycosaminoglycan chemistry for biomolecule delivery

(2013) Tobias Miller et al.   Acta Biomaterialia

Silencing Met receptor tyrosine kinase signaling decreased oral tumor growth and increased survival of nude mice

(2013) X. Tao et al.   ORAL ONCOLOGY

Targeted Disruption of Heparan Sulfate Interaction with Hepatocyte and Vascular Endothelial Growth Factors Blocks Normal and Oncogenic Signaling

(2012) Fabiola Cecchi et al.   CANCER CELL

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Targeting the Hepatocyte Growth Factor–cMET Axis in Cancer Therapy

(2012) George R. Blumenschein et al.   JOURNAL OF CLINICAL ONCOLOGY

Changes in Circulating Pro-Angiogenic Cytokines, other than VEGF, before Progression to Sunitinib Therapy in Advanced Renal Cell Carcinoma Patients

(2012) Camillo Porta et al.   ONCOLOGY

HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop

(2011) Zanobia A Syed et al.   BMC CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion

(2011) Xiao-Guang Yu   INTERNATIONAL JOURNAL OF ONCOLOGY

Epidermal Growth Factor (EGF) Ligand Release by Substrate-specific A Disintegrin and Metalloproteases (ADAMs) Involves Different Protein Kinase C (PKC) Isoenzymes Depending on the Stimulus

(2011) Michelle Dang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombospondin-1: Multiple Paths to Inflammation

(2011) Zenaida Lopez-Dee et al.   MEDIATORS OF INFLAMMATION

HGF-independent potentiation of EGFR action by c-Met

(2011) A M Dulak et al.   ONCOGENE

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

(2011) Q. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

An overview of the c-MET signaling pathway

(2011) Shawna Leslie Organ et al.   Therapeutic Advances in Medical Oncology

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis

(2010) A K Mitra et al.   ONCOGENE

Roles for Growth Factors in Cancer Progression

(2010) Esther Witsch et al.   PHYSIOLOGY

Growth factors in tumor microenvironment

(2009) Xuejing Zhang   Frontiers in Bioscience-Landmark

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

(2009) X. Lu et al.   GENES & DEVELOPMENT

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Crosstalk in Met receptor oncogenesis

(2009) Andrea Z. Lai et al.   TRENDS IN CELL BIOLOGY

Cancer and the tumor microenvironment: a review of an essential relationship

(2008) Flaubert Mbeunkui et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The tumor microenvironment and its contribution to tumor evolution toward metastasis

(2008) Girieca Lorusso et al.   HISTOCHEMISTRY AND CELL BIOLOGY

A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met

(2008) Cristina Basilico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles of ADAM and ADAMTS metalloproteinases in cancer

(2007) N. Rocks et al.   BIOCHIMIE

HGF and c-MET as potential orchestrators of invasive growth in head and neck squamous cell carcinoma

(2007) Maria-Jantine De Herdt   Frontiers in Bioscience-Landmark

Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain

(2007) Barbara Margosio et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY