Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways

A novel sesquiterpene glycoside from Loquat leaf alleviates oleic acid-induced steatosis and oxidative stress in HepG2 cells

(2018) Tunyu Jian et al.   BIOMEDICINE & PHARMACOTHERAPY

Actein ameliorates hepatic steatosis and fibrosis in high fat diet-induced NAFLD by regulation of insulin and leptin resistant

(2018) Hong-Jun Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Alpinetin improved high fat diet-induced non-alcoholic fatty liver disease (NAFLD) through improving oxidative stress, inflammatory response and lipid metabolism

(2018) Yong Zhou et al.   BIOMEDICINE & PHARMACOTHERAPY

Lack of ClC-2 Alleviates High Fat Diet-Induced Insulin Resistance and Non-Alcoholic Fatty Liver Disease

(2018) Dongxia Fu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Long-term exposure to fine particulate matter air pollution and type 2 diabetes mellitus in elderly: A cohort study in Hong Kong

(2018) Hong Qiu et al.   ENVIRONMENT INTERNATIONAL

Hepatic CREBZF couples insulin to lipogenesis by inhibiting insig activity and contributes to hepatic steatosis in diet-induced insulin-resistant mice

(2018) Feifei Zhang et al.   HEPATOLOGY

Elevated expression of miR-146, miR-139 and miR-340 involved in regulating Th1/Th2 balance with acute exposure of fine particulate matter in mice

(2018) Tianfang Hou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers

(2018) Midori Honma et al.   INTERNATIONAL JOURNAL OF OBESITY

Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer

(2018) Sun-Hye Jeong et al.   JOURNAL OF CLINICAL INVESTIGATION

Antitussive and expectorant properties of growing and fallen leaves of loquat ( Eriobotrya japonica )

(2018) Yue-xian Wu et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Chemical characterisation and source identification of atmospheric aerosols in the Snowy Mountains, south-eastern Australia

(2018) Carol V. Tadros et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Antitussive and expectorant properties of growing and fallen leaves of loquat ( Eriobotrya japonica )

(2018) Yue-xian Wu et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver

(2018) Tao Zeng et al.   Redox Biology

Effects of phoxim-induced hepatotoxicity on SD rats and the protection of vitamin E

(2017) Jing Zhang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Rutin exhibits hepatoprotective effects in a mouse model of non-alcoholic fatty liver disease by reducing hepatic lipid levels and mitigating lipid-induced oxidative injuries

(2017) Qingsheng Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antidiabetic and Lipid-Lowering Effects of the Polyphenol Extracts from the Leaves of Clausena lansium (Lour.) Skeels on Streptozotocin-Induced Type 2 Diabetic Rats

(2017) Fansheng Kong et al.   JOURNAL OF FOOD SCIENCE

Flavone protects HBE cells from DNA double-strand breaks caused by PM2.5

(2017) Xing Ren et al.   Human Cell

Airborne PM2.5-Induced Hepatic Insulin Resistance by Nrf2/JNK-Mediated Signaling Pathway

(2017) Jinxia Xu et al.   International Journal of Environmental Research and Public Health

Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways

(2017) Heeyoon Jeong et al.   Scientific Reports

Inhalation Exposure to PM2.5 Counteracts Hepatic Steatosis in Mice Fed High-fat Diet by Stimulating Hepatic Autophagy

(2017) Yining Qiu et al.   Scientific Reports

Extracellular Vesicles: A New Frontier in Biomarker Discovery for Non-Alcoholic Fatty Liver Disease

(2016) Linda Ban et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway

(2016) Khalid Matalka et al.   MOLECULES

Effect of BI-1 on insulin resistance through regulation of CYP2E1

(2016) Geum-Hwa Lee et al.   Scientific Reports

Anti-Obesity Effects of the Mixture of Eriobotrya japonica and Nelumbo nucifera in Adipocytes and High-Fat Diet-Induced Obese Mice

(2015) Bhesh Raj Sharma et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

PM2.5 and Diabetes and Hypertension Incidence in the Black Women’s Health Study

(2015) Patricia F. Coogan et al.   EPIDEMIOLOGY

Induction of CYP2E1 in non-alcoholic fatty liver diseases

(2015) Ghanim Aljomah et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models

(2015) Ze Zheng et al.   JOURNAL OF HEPATOLOGY

Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling

(2014) Jörn M. Schattenberg et al.   Redox Biology

Cell Suspension Culture of Eriobotrya japonica Regulates the Diabetic and Hyperlipidemic Signs of High-Fat-Fed Mice

(2013) Chun-Ching Shih et al.   MOLECULES

Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet

(2013) Lixian Sun et al.   Particle and Fibre Toxicology

Exposure to ambient air particulate matter and non-alcoholic fatty liver disease

(2013) Giovanni Tarantino   WORLD JOURNAL OF GASTROENTEROLOGY

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

(2012) Mohamed A. Abdelmegeed et al.   JOURNAL OF HEPATOLOGY

CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease

(2012) Tung-Ming Leung et al.   JOURNAL OF HEPATOLOGY

Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model

(2012) Ze Zheng et al.   JOURNAL OF HEPATOLOGY

NASH: A global health problem

(2011) Arun J. Sanyal   HEPATOLOGY RESEARCH

Direct effects of iodothyronines on excess fat storage in rat hepatocytes

(2010) Elena Grasselli et al.   JOURNAL OF HEPATOLOGY

Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome

(2009) C. H. KIM et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Hypoglycemic effect of the total flavonoid fraction from Folium Eriobotryae

(2009) H. Lü et al.   PHYTOMEDICINE