Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Preclinical Model of Inflammatory Breast Cancer to Study the Involvement of CXCR4 and ACKR3 in the Metastatic Process

(2015) Roberto Wurth et al.   Translational Oncology

Inhibition of CXCR4 and CXCR7 for reduction of cell proliferation and invasion in human endometrial cancer

(2015) Ping Long et al.   TUMOR BIOLOGY

GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells

(2015) Shingo Inaguma et al.   Oncotarget

Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration

(2015) Dong Chen et al.   Scientific Reports

Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells

(2014) Kirsten Hattermann et al.   CELL AND TISSUE RESEARCH

SDF-1α induces differential trafficking of CXCR4-CXCR7 involving cyclophilin A, CXCR7 ubiquitination and promotes platelet survival

(2014) Madhumita Chatterjee et al.   FASEB JOURNAL

CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression

(2014) L Lin et al.   Cell Death & Disease

Interfering with CXCR4 expression inhibits proliferation, adhesion and migration of breast cancer MDA-MB-231 cells

(2014) SHANYU GUO et al.   Oncology Letters

CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4

(2013) Ayako Uto-Konomi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Optimized Method of G-Protein-Coupled Receptor Homology Modeling: Its Application to the Discovery of Novel CXCR7 Ligands

(2013) Yasushi Yoshikawa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Role of chemokine receptor CXCR7 in bladder cancer progression

(2012) Mingang Hao et al.   BIOCHEMICAL PHARMACOLOGY

Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells

(2012) Eileen L Heinrich et al.   Journal of Translational Medicine

Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells

(2012) K E Luker et al.   ONCOGENE

Involvement of the CXCR7/CXCR4/CXCL12 Axis in the Malignant Progression of Human Neuroblastoma

(2012) Julie Liberman et al.   PLoS One

Akt and ERK Control the Proliferative Response of Mammary Epithelial Cells to the Growth Factors IGF-1 and EGF Through the Cell Cycle Inhibitor p57Kip2

(2012) D. T. Worster et al.   Science Signaling

CXCR7 mediated Giα independent activation of ERK and Akt promotes cell survival and chemotaxis in T cells

(2011) Romsha Kumar et al.   CELLULAR IMMUNOLOGY

CXCL12 (SDF1 )-CXCR4/CXCR7 Pathway Inhibition: An Emerging Sensitizer for Anticancer Therapies?

(2011) D. G. Duda et al.   CLINICAL CANCER RESEARCH

The presumed atypical chemokine receptor CXCR7 signals through Gi/o proteins in primary rodent astrocytes and human glioma cells

(2011) Veysel Ödemis et al.   GLIA

CXCR7/CXCR4 Heterodimer Constitutively Recruits β-Arrestin to Enhance Cell Migration

(2011) Fabien M. Décaillot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

(2011) Yi-fang Ping et al.   JOURNAL OF PATHOLOGY

Cxcr7 Controls Neuronal Migration by Regulating Chemokine Responsiveness

(2011) Juan Antonio Sánchez-Alcañiz et al.   NEURON

CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression

(2010) Xueqing Sun et al.   CANCER AND METASTASIS REVIEWS

The Chemokine Receptor CXCR7 Is Highly Expressed in Human Glioma Cells and Mediates Antiapoptotic Effects

(2010) K. Hattermann et al.   CANCER RESEARCH

Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas

(2010) Katarzyna Grymula et al.   INTERNATIONAL JOURNAL OF CANCER

Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands

(2010) K E Luker et al.   ONCOGENE

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling

(2009) A. Levoye et al.   BLOOD

Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands

(2009) B. A. Zabel et al.   JOURNAL OF IMMUNOLOGY

CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway

(2009) Yumei Wu et al.   JOURNAL OF NEUROCHEMISTRY

CXCR4 dimerization and  -arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome

(2008) B. Lagane et al.   BLOOD

Control of Chemokine-Guided Cell Migration by Ligand Sequestration

(2008) Bijan Boldajipour et al.   CELL

Imaging chemokine receptor dimerization with firefly luciferase complementation

(2008) Kathryn E. Luker et al.   FASEB JOURNAL

Essential but differential role for CXCR4 and CXCR7 in the therapeutic homingof human renal progenitor cells

(2008) Benedetta Mazzinghi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells

(2008) Tanja Nicole Hartmann et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CXCR7, CXCR4 and CXCL12: An eccentric trio?

(2008) Marcus Thelen et al.   JOURNAL OF NEUROIMMUNOLOGY

CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

(2008) J A Burger et al.   LEUKEMIA