In Vivo Glycan Engineering via the Mannosidase I Inhibitor (Kifunensine) Improves Efficacy of Rituximab Manufactured in Nicotiana benthamiana Plants
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Title
In Vivo Glycan Engineering via the Mannosidase I Inhibitor (Kifunensine) Improves Efficacy of Rituximab Manufactured in Nicotiana benthamiana Plants
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 1, Pages 194
Publisher
MDPI AG
Online
2019-01-09
DOI
10.3390/ijms20010194
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Note: Only part of the references are listed.- Implementation of Glycan Remodeling to Plant-Made Therapeutic Antibodies
- (2018) Lindsay Bennett et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Sugata Roychowdhury et al. Frontiers in Plant Science
- N-glycan Remodeling Using Mannosidase Inhibitors to Increase High-mannose Glycans on Acid α-Glucosidase in Transgenic Rice Cell Cultures
- (2018) Hong-Yeol Choi et al. Scientific Reports
- Comparability study of Rituximab originator and follow-on biopharmaceutical
- (2017) Othman Montacir et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Modulating IgG effector function by Fc glycan engineering
- (2017) Tiezheng Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Immunoregulatory Roles of Antibody Glycosylation
- (2017) Madeleine F. Jennewein et al. TRENDS IN IMMUNOLOGY
- Plant protein glycosylation
- (2016) Richard Strasser GLYCOBIOLOGY
- Techno-economic analysis of a transient plant-based platform for monoclonal antibody production
- (2016) Somen Nandi et al. mAbs
- Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels
- (2015) Craig Zupke et al. BIOTECHNOLOGY PROGRESS
- Fc glycans of therapeutic antibodies as critical quality attributes
- (2015) Dietmar Reusch et al. GLYCOBIOLOGY
- Multiplexed, targeted gene editing inNicotiana benthamianafor glyco-engineering and monoclonal antibody production
- (2015) Jin Li et al. PLANT BIOTECHNOLOGY JOURNAL
- Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals
- (2015) Barry R. Holtz et al. PLANT BIOTECHNOLOGY JOURNAL
- N-Glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential
- (2015) Krystal Teasley Hamorsky et al. Scientific Reports
- Mogamulizumab and the treatment of CCR4-positive T-cell lymphomas
- (2014) Marcus Remer et al. Immunotherapy
- The therapeutic monoclonal antibody market
- (2014) Dawn M Ecker et al. mAbs
- Type I and type II Fc receptors regulate innate and adaptive immunity
- (2014) Andrew Pincetic et al. NATURE IMMUNOLOGY
- IgG Subclasses and Allotypes: From Structure to Effector Functions
- (2014) Gestur Vidarsson et al. Frontiers in Immunology
- Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions
- (2012) Wei Huang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Increased serum clearance of oligomannose species present on a human IgG1 molecule
- (2012) Leslie Alessandri et al. mAbs
- Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans
- (2012) Marcella Yu et al. mAbs
- High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans
- (2011) A. M. Goetze et al. GLYCOBIOLOGY
- Inhibition of Endoplasmic Reticulum-associated Degradation Rescues Native Folding in Loss of Function Protein Misfolding Diseases
- (2011) Fan Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of gene-activated human acid- -glucosidase: Crystal structure, glycan composition, and internalization into macrophages
- (2009) B. Brumshtein et al. GLYCOBIOLOGY
- Down-regulated expression of plant-specific glycoepitopes in alfalfa
- (2008) Christophe Sourrouille et al. PLANT BIOTECHNOLOGY JOURNAL
- Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure
- (2008) Richard Strasser et al. PLANT BIOTECHNOLOGY JOURNAL
- Effect of constant and variable domain glycosylation on pharmacokinetics of therapeutic antibodies in mice
- (2007) Thomas A. Millward et al. BIOLOGICALS
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