Risk of delayed bleeding after hemorrhoidectomy

PurposeDelayed post-hemorrhoidectomy bleeding (DPHB) is a rare but serious complication. We investigated the incidence and risk factors of DPHB in patients undergoing hemorrhoidectomy using the LigaSure device or the Ferguson procedure.MethodsThis retrospective study included 382 consecutive patients with symptomatic grades II to IV hemorrhoids who received either LigaSure (184 patients) or Ferguson (198 patients) hemorrhoidectomy procedures. Thirty-two patients who experienced DPHB after discharge were followed up.ResultsSignificantly fewer Ferguson group patients had DPHB compared to the LigaSure group (5.1% vs. 11.9%; P=0.015). In the overall population, the risk of DPHB was higher in (1) males compared to that of females (OR=3.39; 95% CI 1.50-7.69, P=0.003); (2) in the LigaSure group compared to the Ferguson group (OR=2.77; 95% CI 1.23-6.24, P=0.01); and (3) in patients with constipation (OR=6.59; 95% CI 2.73-15.89, P<0.0001). Males in the LigaSure group had a significantly higher rate of delayed bleeding than those in the Ferguson group (20% vs. 5.8%, P=0.004); no significant differences were found in females (4.9% vs. 4.5%, P=0.878). Subgroup analysis showed that in males, risk of DPHB increased significantly with postoperative constipation (OR=4.73, 95% CI 1.45-15.43, P=0.010) and the LigaSure procedure (OR=3.99, 95% CI 1.37-11.62, P=0.011). In females, the risk of DPHB was significantly associated with postoperative constipation (OR=8.80, 95% CI 2.24-34.54, P=0.002).ConclusionsThe LigaSure procedure and constipation are independent risk factors for DPHB in patients undergoing hemorrhoidectomy and can be used as predictors of outcome.