Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-β

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Title
Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-β
Authors
Keywords
-
Journal
BIOCHEMISTRY
Volume 54, Issue 10, Pages 1918-1929
Publisher
American Chemical Society (ACS)
Online
2015-02-24
DOI
10.1021/bi5015425

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