Basics of memory B-cell responses: lessons from and for the real world

An Immunocompetent Mouse Model of Zika Virus Infection

(2018) Matthew J. Gorman et al.   Cell Host & Microbe

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

(2018) Robert K. Abbott et al.   IMMUNITY

Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM + and Transient IgG + Memory B Cells

(2018) Kathryn A. Pape et al.   IMMUNITY

Generation of memory B cells and their reactivation

(2018) Takeshi Inoue et al.   IMMUNOLOGICAL REVIEWS

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus

(2018) Estefania Fernandez et al.   mBio

Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function

(2018) Wing Y. Lam et al.   Cell Reports

Age-Associated B Cells Express a Diverse Repertoire of VHand Vκ Genes with Somatic Hypermutation

(2017) Lisa M. Russell Knode et al.   JOURNAL OF IMMUNOLOGY

Dengvaxia sensitizes seronegatives to vaccine enhanced disease regardless of age

(2017) Scott B. Halstead   VACCINE

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

(2017) Dana Piovesan et al.   Cell Reports

Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells

(2017) Nyamekye Obeng-Adjei et al.   PLoS Pathogens

Structural Basis of Zika Virus-Specific Antibody Protection

(2016) Haiyan Zhao et al.   CELL

Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory

(2016) Alexander D. Gitlin et al.   IMMUNITY

A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

(2016) Florian J. Weisel et al.   IMMUNITY

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

(2016) Wing Y. Lam et al.   IMMUNITY

Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

(2016) Akshay T. Krishnamurty et al.   IMMUNITY

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

(2016) Joanne H. Reed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fc Receptor–like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue–like Memory B Cells

(2016) Huifang Li et al.   JOURNAL OF IMMUNOLOGY

ZBTB32 Restricts the Duration of Memory B Cell Recall Responses

(2016) Arijita Jash et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-10 Is Essential for the Generation of Germinal Center B Cell Responses and Anti-PlasmodiumHumoral Immunity

(2016) Jenna J. Guthmiller et al.   JOURNAL OF IMMUNOLOGY

B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts

(2016) Lalita Priyamvada et al.   JOURNAL OF VIROLOGY

Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere

(2016) Helen M. Lazear et al.   JOURNAL OF VIROLOGY

Structural basis of potent Zika–dengue virus antibody cross-neutralization

(2016) Giovanna Barba-Spaeth et al.   NATURE

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

(2016) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

(2016) Lalita Priyamvada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

(2016) K. Stettler et al.   SCIENCE

Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein

(2016) Gladys J. Keitany et al.   Cell Reports

Plasmablasts During Acute Dengue Infection Represent a Small Subset of a Broader Virus-specific Memory B Cell Pool

(2016) Ramapraba Appanna et al.   EBioMedicine

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

(2015) Michael T White et al.   LANCET INFECTIOUS DISEASES

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

(2015) Joshua Tan et al.   NATURE

Apoptosis and antigen affinity limit effector cell differentiation of a single naive B cell

(2015) J. J. Taylor et al.   SCIENCE

Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children

(2015) Nyamekye Obeng-Adjei et al.   Cell Reports

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

(2015) Silvia Portugal et al.   eLife

Adjuvant-specific regulation of long-term antibody responses by ZBTB20

(2014) Yinan Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

(2014) Griselda V Zuccarino-Catania et al.   NATURE IMMUNOLOGY

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

(2014) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Identification and characterization of the constituent human serum antibodies elicited by vaccination

(2014) Jason J. Lavinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

(2014) Z. Sabouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flavivirus-Mosquito Interactions

(2014) Yan-Jang Huang et al.   Viruses-Basel

Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell Differentiation

(2013) Kohei Kometani et al.   IMMUNITY

Atypical and classical memory B cells producePlasmodium falciparumneutralizing antibodies

(2013) Matthias F. Muellenbeck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune Tolerance Negatively Regulates B Cells in Knock-In Mice Expressing Broadly Neutralizing HIV Antibody 4E10

(2013) C. Doyle-Cooper et al.   JOURNAL OF IMMUNOLOGY

Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure

(2013) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα

(2012) Nathaniel S Wang et al.   NATURE IMMUNOLOGY

A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

(2011) Y. Hao et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

(2011) Whitney E. Purtha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Unique Role of the Cholera Toxin A1-DD Adjuvant for Long-Term Plasma and Memory B Cell Development

(2011) M. Bemark et al.   JOURNAL OF IMMUNOLOGY

Persistence of Circulating Memory B Cell Clones with Potential for Dengue Virus Disease Enhancement for Decades following Infection

(2011) S. A. Smith et al.   JOURNAL OF VIROLOGY

A Positive Correlation between Atypical Memory B Cells and Plasmodium falciparum Transmission Intensity in Cross-Sectional Studies in Peru and Mali

(2011) Greta E. Weiss et al.   PLoS One

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Enhanced Infection of Liver Sinusoidal Endothelial Cells in a Mouse Model of Antibody-Induced Severe Dengue Disease

(2010) Raphaël M. Zellweger et al.   Cell Host & Microbe

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

(2010) Martina Beltramello et al.   Cell Host & Microbe

Cross-Reacting Antibodies Enhance Dengue Virus Infection in Humans

(2010) W. Dejnirattisai et al.   SCIENCE

The Plasmodium falciparum-Specific Human Memory B Cell Compartment Expands Gradually with Repeated Malaria Infections

(2010) Greta E. Weiss et al.   PLoS Pathogens

Atypical Memory B Cells Are Greatly Expanded in Individuals Living in a Malaria-Endemic Area

(2009) G. E. Weiss et al.   JOURNAL OF IMMUNOLOGY

The TLR9 Ligand CpG Promotes the Acquisition of Plasmodium falciparum-Specific Memory B Cells in Malaria-Naive Individuals

(2009) P. D. Crompton et al.   JOURNAL OF IMMUNOLOGY

Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts

(2009) T. D. Chan et al.   JOURNAL OF IMMUNOLOGY

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali

(2009) Boubacar Traore et al.   VACCINE

Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody

(2009) W.M.P.B. Wahala et al.   VIROLOGY

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

(2008) C.-Y. Lai et al.   JOURNAL OF VIROLOGY