Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 41, Issue 1, Pages 170-176Publisher
WILEY
DOI: 10.1002/hed.25485
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Objectives To evaluate and compare the diagnostic potential of F-18-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ((18)FDG-PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC). Methods A total of 32 dedicated head and neck F-18-FDG PET/MRI datasets were included in this analysis. MRI and F-18-FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases. Results Lesion-based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for F-18-FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of F-18-FDG PET/MRI compared to MRI (P < .005). Conclusion F-18-FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, F-18-FDG PET/MRI outperforms MRI.
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