Journal
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Volume 257, Issue 2, Pages 279-288Publisher
SPRINGER
DOI: 10.1007/s00417-018-4201-8
Keywords
Central serous chorioretinopathy; Fluorescein angiography; Indocyanine green angiography; Imaging; Optical coherence tomography; Pachychoroid; Photo dynamic therapy; Polypoidal choroidal vasculopathy
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Funding
- National Research Foundation of Korea (NRF) - Ministry of Science, ICT and Future Planning [NRF-2017R1D1A1B03034695]
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PurposeTo investigate the angiographic, tomographic, and clinical characteristics of idiopathic central serous chorioretinopathy (CSC) in elderly patients.MethodsThe patients were divided into two groups according to a cutoff age of 60years at baseline. Patients underwent spectral domain optical coherence tomography, fluorescein angiography, and indocyanine green angiography. Angiographic and tomographic features were compared between the two groups (young vs. elderly group).ResultsOf 176 patients, 26 patients (15.1%) were 60years or older. Complete resolution of subretinal fluid after treatment was noted in 72.0% of the elderly group and 90.8% of the young group (P=0.021). The elderly group showed worse baseline and final vision, more bilateral involvement, and lower male preponderance than the young group (P<0.05, respectively). The elderly group was also associated with a higher frequency of retinal pigment epithelium depigmentation, foveal thinning, and double-layer sign compared with the young group (P<0.05, respectively).ConclusionCSC in elderly patients was associated with a lower resolution of serous detachment, increased impairment of retinal pigment epithelial layers, foveal thinning, and worse visual outcome, suggesting a chronic insult to the choroidal vessels involving more severe damage to the outer retinal layers.
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