Constrained instruments and their application to Mendelian randomization with pleiotropy

Instrumental Variables Estimation With Some Invalid Instruments and its Application to Mendelian Randomization

(2016) Hyunseung Kang et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects

(2015) S. Burgess et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Robust Estimation for Secondary Trait Association in Case-Control Genetic Studies

(2014) J. d. D. Tapsoba et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Lack of Identification in Semiparametric Instrumental Variable Models With Binary Outcomes

(2014) Stephen Burgess et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The many weak instruments problem and Mendelian randomization

(2014) Neil M. Davies et al.   STATISTICS IN MEDICINE

A general regression framework for a secondary outcome in case-control studies

(2013) E. J. Tchetgen Tchetgen   BIOSTATISTICS

Use of allele scores as instrumental variables for Mendelian randomization

(2013) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Commentary: Building an evidence base for mendelian randomization studies: assessing the validity and strength of proposed genetic instrumental variables

(2013) Eric J Tchetgen Tchetgen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Instrumental Variable Estimators for Binary Outcomes

(2012) Paul S. Clarke et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Avoiding bias from weak instruments in Mendelian randomization studies

(2011) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Why Pleiotropic Interventions are Needed for Alzheimer's Disease

(2010) Sally A. Frautschy et al.   MOLECULAR NEUROBIOLOGY

Mendelian randomization analysis of case-control data using structural mean models

(2010) Jack Bowden et al.   STATISTICS IN MEDICINE

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Illustrating bias due to conditioning on a collider

(2009) Stephen R Cole et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proper analysis of secondary phenotype data in case-control association studies

(2008) D. Y. Lin et al.   GENETIC EPIDEMIOLOGY

Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses

(2008) Tom M Palmer et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

‘Mendelian randomization’ equals instrumental variable analysis with genetic instruments

(2008) George L. Wehby et al.   STATISTICS IN MEDICINE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE