SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

Adiposity, Type 2 Diabetes, and Alzheimer's Disease

(2017) José A. Luchsinger et al.   JOURNAL OF ALZHEIMERS DISEASE

Metabolic Inflammation-Differential Modulation by Dietary Constituents

(2016) Claire Lyons et al.   Nutrients

Inflammatory cause of metabolic syndrome via brain stress and NF-κB

(2016) Dongsheng Cai et al.   Aging-US

Hypothalamic Gliosis Associated With High-Fat Diet Feeding Is Reversible in Mice: A Combined Immunohistochemical and Magnetic Resonance Imaging Study

(2014) Kathryn E. Berkseth et al.   ENDOCRINOLOGY

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

(2014) Jae Geun Kim et al.   NATURE NEUROSCIENCE

Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery

(2014) Sten Madsbad et al.   Lancet Diabetes & Endocrinology

Hormones and diet, but not body weight, control hypothalamic microglial activity

(2013) Yuanqing Gao et al.   GLIA

Acute Inhibition of Central c-Jun N-terminal Kinase Restores Hypothalamic Insulin Signalling and Alleviates Glucose Intolerance in Diabetic Mice

(2013) J. Benzler et al.   JOURNAL OF NEUROENDOCRINOLOGY

High-Fat Diet Induces Leptin Resistance in Leptin-Deficient Mice

(2013) C. E. Koch et al.   JOURNAL OF NEUROENDOCRINOLOGY

Regional astrogliosis in the mouse hypothalamus in response to obesity

(2012) Laura B. Buckman et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Hypothalamic dysfunction in obesity

(2012) Lynda M. Williams   PROCEEDINGS OF THE NUTRITION SOCIETY

Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the ugly

(2011) F. Sardi et al.   AUTOIMMUNITY REVIEWS

Hepatic acute phase proteins – Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling

(2011) Johannes G. Bode et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Minireview: Inflammation and Obesity Pathogenesis: The Hypothalamus Heats Up

(2010) Joshua P. Thaler et al.   ENDOCRINOLOGY

Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity

(2010) C. Koch et al.   JOURNAL OF NEUROSCIENCE

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Obesity: Why be Concerned?

(2009) W. Virgil Brown et al.   AMERICAN JOURNAL OF MEDICINE

MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity

(2009) André Kleinridders et al.   Cell Metabolism

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation

(2008) Michela Baccini et al.   Genes and Nutrition