Article
Surgery
Ryan Lamm, D. Brock Hewitt, Michael Li, Adam C. Powell, Adam C. Berger
Summary: This study used a national cancer database to analyze the association between socioeconomic factors and gastric cancer surgical outcomes. The results showed that lower income and lower level of education at the place of residence were independently associated with higher 30-day and 90-day mortality rates.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Chen Yuan, Hee-Kyung Joh, Qiao-Li Wang, Yin Zhang, Stephanie A. Smith-Warner, Molin Wang, Mingyang Song, Yin Cao, Xuehong Zhang, Emilie S. Zoltick, Jinhee Hur, Andrew T. Chan, Jeffrey A. Meyerhardt, Shuji Ogino, Kimmie Ng, Edward L. Giovannucci, Kana Wu
Summary: Long-term consumption of sugar-sweetened beverages (SSBs) and total fructose intake are associated with increased incidence and mortality of proximal colon cancer, particularly during later stages of tumorigenesis.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Oncology
Harinakshi Sanikini, Carine Biessy, Sabina Rinaldi, Anne-Sophie Navionis, Audrey Gicquiau, Pekka Keski-Rahkonen, Agneta Kiss, Stephanie J. Weinstein, Demetrius Albanes, Antonio Agudo, Mazda Jenab, Elio Riboli, Marc J. Gunter, Gwen Murphy, Amanda J. Cross
Summary: This study found a positive association between obesity and gastric cancer. The impact of excess fat on hormones has been implicated in the development of cancer. The results show that certain obesity-related hormones are closely related to the risk of cardia gastric cancer and non-cardia gastric cancer.
Review
Oncology
Ernesto Sosa, Gail D'Souza, Aamna Akhtar, Melissa Sur, Kyra Love, Jeanette Duffels, Dan J. Raz, Jae Y. Kim, Virginia Sun, Loretta Erhunmwunsee
Summary: This study investigates the inequalities in lung cancer screening (LCS) and finds significant disparities along racial and socioeconomic lines. Black and socioeconomically disadvantaged individuals miss out on potential benefits of LCS along the pipeline, resulting in increased mortality rates.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Article
Oncology
Qiang Wang, Xiaorui Zhang, Yuxin Zhong, Shijing Wei, Li Li, Wenqiang Wei, Fen Liu, Yong Li, Shaoming Wang
Summary: This study aimed to investigate the clinical characteristics and changing trajectories of gastric cancer (GC) and esophageal cancer (EC). Data from a large cancer hospital in Beijing, China, from 2010 to 2019 were collected and analyzed using joinpoint regression. The results showed an increasing trend of EC and GC patients diagnosed at stage I, with metabolic comorbidities, such as hypertension, being the most common. The prioritized subtype of EC was esophageal squamous cell carcinoma, while adenocarcinoma accounted for the majority of GC cases. The findings provide evidence for guiding future treatment strategies.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Farhad Islami, Jordan Baeker Bispo, Hyunjung Lee, Daniel Wiese, K. Robin Yabroff, Priti Bandi, Kirsten Sloan, Alpa V. Patel, Elvan C. Daniels, Arif H. Kamal, Carmen E. Guerra, William L. Dahut, Ahmedin Jemal
Summary: The American Cancer Society has published a report on cancer disparities in the United States, highlighting the significant variations in cancer occurrence and outcomes based on race, ethnicity, socioeconomic factors, and geographic location. Black and American Indian/Alaska Native individuals face higher cancer mortality rates, and education level and residential area also contribute to these disparities. The report emphasizes the importance of addressing social determinants of health and implementing equitable policies and interventions to reduce cancer disparities.
CA-A CANCER JOURNAL FOR CLINICIANS
(2023)
Article
Oncology
Farhad Islami, Carmen E. Guerra, Adair Minihan, K. Robin Yabroff, Stacey A. Fedewa, Kirsten Sloan, Tracy L. Wiedt, Blake Thomson, Rebecca L. Siegel, Nigar Nargis, Robert A. Winn, Lisa Lacasse, Laura Makaroff, Elvan C. Daniels, Alpa Patel, William G. Cance, Ahmedin Jemal
Summary: This report provides comprehensive data on disparities in cancer occurrence, risk factors, and access to preventive measures and screening in the US. Policy recommendations are made to reduce these inequalities, emphasizing the need for broad implementation of evidence-based interventions to address social inequities and systemic racism.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Gastroenterology & Hepatology
Baskar Balakrishnan, Vaithinathan Selvaraju, Jun Chen, Priscilla Ayine, Lu Yang, Jeganathan Ramesh Babu, Thangiah Geetha, Veena Taneja
Summary: This study aimed to investigate the differences in gut and oral microbial communities in obese African American and European American children, indicating a specific association between ethnicity and microbial profiles.
Article
Cardiac & Cardiovascular Systems
Ashwin S. Nathan, Kriyana P. Reddy, Lin Yang, Lauren A. Eberly, Elias J. Dayoub, Sameed A. M. Khatana, Howard M. Julien, Nimesh D. Desai, Wilson Y. Szeto, Howard C. Herrmann, Taisei J. Kobayashi, Paul Fiorilli, Wayne B. Batchelor, Roxana Mehran, Mohamad Adnan Alkhouli, Jay Giri, Peter W. Groeneveld, Alexander C. Fanaroff
Summary: Racial and ethnic minority and socioeconomically disadvantaged patients are underrepresented in clinical trials. Efforts to enhance inclusion of minority groups have focused on participating sites, but there may be differences in patient populations.
Article
Ethnic Studies
Eduardo J. Santiago-Rodriguez, Natalie A. Rivadeneira, Jacqueline M. Torres, Urmimala Sarkar, Robert A. Hiatt
Summary: In this study, lower socioeconomic status was associated with lower adherence to colorectal cancer screening guidelines, with retirement being a predictor of compliance. There was evidence of heterogeneity in associations between socioeconomic status and CRC screening by race/ethnicity. Insights from the life circumstances of retired individuals could be valuable for designing interventions aimed at improving CRC screening uptake in priority groups.
ETHNICITY & HEALTH
(2022)
Editorial Material
Oncology
Inas Abuali, Shruti Patel, Lauren Kiel, Kelly Meza, Narjust Florez
Summary: Disparities in cancer care disproportionately impact minority groups, who face challenges in accessing high-quality care, are underrepresented in clinical trials, and experience financial toxicity and discrimination during their cancer journey. Diversifying the workforce, improving trial access, and allocating research funding for equitable initiatives should be prioritized.
Article
Public, Environmental & Occupational Health
Giulia Collatuzzo, Gianfranco Alicandro, Paola Bertuccio, Claudio Pelucchi, Rossella Bonzi, Domenico Palli, Monica Ferraroni, Weimin Ye, Amelie Plymoth, David Zaridze, Dmitry Maximovich, Nuria Aragones, Gemma Castano-Vinyals, Jesus Vioque, Manoli Garcia de la Hera, Zuo-Feng Zhang, Jinfu Hu, Lizbeth Lopez-Carrillo, Malaquias Lopez-Cervantes, Michela Dalmartello, Lina Mu, Mary H. Ward, Charles Rabkin, Guo-Pei Yu, M. Constanza Camargo, Maria Paula Curado, Nuno Lunet, Eva Negri, Carlo La Vecchia, Paolo Boffetta
Summary: This study investigates the mediating role of peptic ulcer disease (PUD) in the association between established risk factors and gastric cancer (GC). The results show that smoking is the main cause of gastric mucosal damage, while other risk factors have a smaller mediating effect.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Xianghui Yang, Liyong Deng, Min Li, Yongjie Zhou, Guihua Wang
Summary: This study evaluated the association between socioeconomic status (SES) factors and cancer-specific survival (CSS) in patients with non-small cell lung cancer (NSCLC). A novel TNM-SES staging system was proposed, which showed superior predictive value compared to the traditional TNM stage.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Xuan Quy Luu, Kyeongmin Lee, Jae Kwan Jun, Mina Suh, Kui Son Choi
Summary: Socioeconomic inequality in gastric cancer screening in Korea was evaluated in this study. Organized screening rates have increased gradually over time and account for the majority of screenings, while opportunistic screening rates have decreased. Educational inequality was observed in both types of screening, with negative values in organized screening and positive values in opportunistic screening. Income inequality was not found in organized screening, but was present in opportunistic screening.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Oncology
Margherita Pizzato, Jan Ivar Martinsen, Sanna Heikkinen, Jerome Vignat, Elsebeth Lynge, Par Sparen, Carlo La Vecchia, Eero Pukkala, Salvatore Vaccarella
Summary: This study found significant socioeconomic inequalities in the incidence of the three main lung cancer histotypes in the Nordic countries, with these inequalities increasing, particularly among women. Smoking habits are likely to largely explain the observed social gradient for lung cancer histotypes in both sexes.
Article
Oncology
Bashir Dabo, Claudio Pelucchi, Matteo Rota, Harshonnati Jain, Paola Bertuccio, Rossella Bonzi, Domenico Palli, Monica Ferraroni, Zuo-Feng Zhang, Aurora Sanchez-Anguiano, Yen Thi-Hai Pham, Chi Thi-Du Tran, Anh Gia Pham, Guo-Pei Yu, Tin C. Nguyen, Joshua Muscat, Shoichiro Tsugane, Akihisa Hidaka, Gerson S. Hamada, David Zaridze, Dmitry Maximovitch, Manolis Kogevinas, Nerea Fernandez de Larrea, Stefania Boccia, Roberta Pastorino, Robert C. Kurtz, Areti Lagiou, Pagona Lagiou, Jesus Vioque, M. Constanza Camargo, Maria Paula Curado, Nuno Lunet, Paolo Boffetta, Eva Negri, Carlo La Vecchia, Hung N. Luu
Summary: This study investigated the association between type 2 diabetes and gastric cancer using data from an international consortium. The results showed that there was no overall association between diabetes and gastric cancer, but there was a significant association between diabetes and cardia gastric cancer risk.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2022)
Article
Oncology
Minkyo Song, Charles S. Rabkin, Hidemi Ito, Isao Oze, Yuriko N. Koyanagi, Ruth M. Pfeiffer, Yumiko Kasugai, Keitaro Matsuo, M. Constanza Camargo
Summary: The study did not identify any inflammation-related biomarkers that may be useful for early disease detection. Further investigation of other biomarkers is warranted.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2022)
Article
Substance Abuse
Kim Pulvers, LaRee Tracy, Thomas E. Novotny, Nora Satybaldiyeva, Adam Hunn, Devan R. Romero, Nathan G. Dodder, Jose Magraner, Eyal Oren
Summary: The study found that filtered cigarettes were perceived as more enjoyable and less harsh compared to unfiltered cigarettes. Participants smoked filtered cigarettes at a higher rate during the trial. However, there was no significant difference in nicotine dependence or intention to quit between the two conditions.
Editorial Material
Gastroenterology & Hepatology
Samir Gupta, Aaron P. Thrift
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Samir Gupta, Ashley Earles, Ranier Bustamante, Olga V. Patterson, Andrew J. Gawron, Tonya R. Kaltenbach, Hanin Yassin, Mark Lamm, Shailja C. Shah, Sameer Dev Saini, Deborah A. Fisher, Maria Elena Martinez, Karen Messer, Joshua Demb, Lin Liu
Summary: In this study, the colonoscopist's adenoma detection rate (ADR) was found to be independently associated with the risk of moderate-to-high complexity adenomas. Compared to the highest quintile (ADR >47.0%), the risk of moderate-to-high complexity adenomas increased by 1.48- to 1.66-fold in the lowest 3 quintiles (ADR <19.7%-39.3%).
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Mehul Trivedi, Suha Godil, Joshua Demb, Ashley Earles, Ranier Bustamante, Olga Patterson, Andrew J. Gawron, Tonya Kaltenbach, Sumana Mahata, Lin Liu, Samir Gupta
Summary: This study aimed to investigate the clinical characteristics and long-term outcomes associated with traditional serrated adenomas (TSAs). The results showed that TSA patients have an increased risk for colorectal cancer (CRC) and a risk of developing other high-risk neoplasia during follow-up surveillance colonoscopy.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Eric E. Low, Rena Yadlapati, Lin Liu, Ranier Bustamante, Samir Gupta
Summary: The study team established a large cohort of individuals with achalasia within the Veterans Health Administration (VHA), allowing for further investigation of risk factors and outcomes of this esophageal motility disorder.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Lusheng Song, Minkyo Song, Charles S. Rabkin, Yunro Chung, Stacy Williams, Javier Torres, Alejandro H. Corvalan, Robinson Gonzalez, Enrique Bellolio, Mahasish Shome, Joshua LaBaer, Ji Qiu, M. Constanza Camargo
Summary: Our study provides a comprehensive assessment of anti-H. pylori antibody profiles in gastric intestinal metaplasia (IM). The identified novel antibodies against target antigens, in addition to CagA, may play a role in the progression of IM. Specific H. pylori antibodies, along with other biomarkers, can help identify IM patients for surveillance.
JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Yas Casey, Joshua Demb, Ngozi Enwerem, Lin Liu, Christian Jackson, Ashley Earles, Ranier Bustamante, Sumana Mahata, Shailja Shah, Samir Gupta
Summary: Young-onset advanced adenoma diagnosis is associated with an 8-fold increased risk of incident colorectal cancer compared with normal colonoscopy. However, the cumulative incidence and mortality of colorectal cancer at 10 years among individuals with either young onset non-advanced or advanced adenoma diagnosis were both relatively low.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Eric E. Low, Qingyuan Song, Rena Yadlapati, Evan S. Dellon, Seema Aceves, Lin Liu, Samir Gupta, Yash A. Choksi, Shailja C. Shah
Summary: Researchers developed and validated two highly accurate coding algorithms for EoE, establishing a nationwide VHA cohort for adults with EoE for future studies.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Fay Kastrinos, Sonia S. Kupfer, Samir Gupta
Summary: Current colorectal cancer (CRC) screening recommendations are based on age, but precision screening using additional factors could improve outcomes and resource utilization. Prediction models can identify high-risk groups for more intensive screening and low-risk groups for less invasive screening. Developing reliable and accurate prediction models and studying their feasibility and cost-effectiveness are critical for future implementation of precision CRC screening.
Letter
Gastroenterology & Hepatology
M. Blanca Piazuelo, Fatima Carneiro, M. Constanza Camargo
Article
Nutrition & Dietetics
Giulia Collatuzzo, Eva Negri, Claudio Pelucchi, Rossella Bonzi, Federica Turati, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Domenico Palli, Monica Ferraroni, Lizbeth Lopez-Carrillo, Nuno Lunet, Samantha Morais, Demetrius Albanes, Stephanie J. Weinstein, Dominick Parisi, David Zaridze, Dmitry Maximovitch, Trinidad Dierssen-Sotos, Jose Juan Jimenez-Moleon, Jesus Vioque, Manoli Garcia de la Hera, Maria Paula Curado, Emmanuel Dias-Neto, Raul Ulises Hernandez-Ramirez, Malaquias Lopez-Cervantes, Mary H. Ward, Shoichiro Tsugane, Akihisa Hidaka, Areti Lagiou, Pagona Lagiou, Zuo-Feng Zhang, Antonia Trichopoulou, Anna Karakatsani, Maria Constanza Camargo, Carlo La Vecchia, Paolo Boffetta
Summary: A meta-analysis of 16 studies found no significant association between yoghurt consumption and gastric cancer risk.
Editorial Material
Health Care Sciences & Services
Arnoldo Riquelme, Christian C. Abnet, Karen J. Goodman, M. Blanca Piazuelo, Erika Ruiz-Garcia, Paulo Pimentel de Assumpcao, M. Constanza Camargo
LANCET REGIONAL HEALTH-AMERICAS
(2023)
Article
Oncology
Minkyo Song, Harindra Jayasekara, Claudio Pelucchi, Charles S. Rabkin, Kenneth C. Johnson, Jinfu Hu, Domenico Palli, Monica Ferraroni, Linda M. Liao, Rossella Bonzi, David Zaridze, Dmitry Maximovitch, Nuria Aragones, Vicente Martin, Gemma Castano-Vinyals, Marcela Guevara, Shoichiro Tsugane, Gerson Shigueaki Hamada, Akihisa Hidaka, Eva Negri, Mary H. Ward, Rashmi Sinha, Areti Lagiou, Pagona Lagiou, Paolo Boffetta, Maria Paula Curado, Nuno Lunet, Jesus Vioque, Zuo-Feng Zhang, Carlo La Vecchia, M. Constanza Camargo
Summary: This study aims to investigate and quantify the relationship between reproductive factors, menopausal hormone therapy (MHT), and gastric cancer risk in women. The results suggest a lower risk of gastric cancer in women with a longer duration of fertility and those who have used MHT after menopause.
CANCER CAUSES & CONTROL
(2023)
